Front Cover
Cover Image © Wiley-VCH GmbH. The image is part of a figure in the article DOI:10.1002/pmic.201900203 by Lei Li, Yong Jiang et al. (Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: FRONT COVER Source Type: research

Contents: Proteomics 5'24
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: CONTENTS Source Type: research

Editorial Board: Proteomics 5'24
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: EDITORIAL BOARD Source Type: research

Standard abbreviations
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: STANDARD ABBREVIATIONS Source Type: research

Beyond the model organism —Mechanistic analysis of protein post‐translational modifications is ready for all challengers
AbstractA historic challenge for shotgun proteomics has been the requirement for high quality, simple, and nonredundant curated protein sequences in small .fasta text files. Due to the intrinsic informatic challenges and time required to assemble these files, proteomics has struggled to expand beyond the confines of a few model organisms. When considering post-translational modifications that may or may not be present on a specific peptide sequence, these factors inevitably compound. A study on how mangos continue to ripen on the shelf may not be the first thing you'd think of as proof of a scientific discipline shedding h...
Source: Proteomics - March 4, 2024 Category: Biochemistry Authors: Benjamin C. Orsburn Tags: COMMENTARY Source Type: research

Front Cover
Cover Image © Wiley-VCH GmbH. The image is part of a figure in the article DOI:10.1002/pmic.201900203 by Lei Li, Yong Jiang et al. (Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: FRONT COVER Source Type: research

Contents: Proteomics 5'24
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: CONTENTS Source Type: research

Editorial Board: Proteomics 5'24
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: EDITORIAL BOARD Source Type: research

Standard abbreviations
(Source: Proteomics)
Source: Proteomics - March 4, 2024 Category: Biochemistry Tags: STANDARD ABBREVIATIONS Source Type: research

Beyond the model organism —Mechanistic analysis of protein post‐translational modifications is ready for all challengers
AbstractA historic challenge for shotgun proteomics has been the requirement for high quality, simple, and nonredundant curated protein sequences in small .fasta text files. Due to the intrinsic informatic challenges and time required to assemble these files, proteomics has struggled to expand beyond the confines of a few model organisms. When considering post-translational modifications that may or may not be present on a specific peptide sequence, these factors inevitably compound. A study on how mangos continue to ripen on the shelf may not be the first thing you'd think of as proof of a scientific discipline shedding h...
Source: Proteomics - March 4, 2024 Category: Biochemistry Authors: Benjamin C. Orsburn Tags: COMMENTARY Source Type: research

Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA
This study provides some new insights into the response of ω-3 PUFAs treatment and a better understanding of cancer cell migration and invasion modulation. (Source: Proteomics)
Source: Proteomics - March 3, 2024 Category: Biochemistry Authors: Chao He, Xiuyuan Chen, Ying Chen, Jianying Sun, Manting Qi, Sonia Rocha, Mu Wang Tags: RESEARCH ARTICLE Source Type: research

Prolonged exposure to dexamethasone alters the proteome and cellular phenotype of human testicular peritubular cells
AbstractHuman testicular peritubular cells (HTPCs) are smooth muscle cells, which in the testis form a small compartment surrounding the seminiferous tubules. Contractions of HTPCs are responsible for sperm transport, HTPCs contribute to spermatogenesis, have immunological roles and are a site of glucocorticoid receptor expression. Importantly, HTPCs maintain their characteristics in vitro, and thus can serve as an experimental window into the male gonad. Previously we reported consequences of 3-day treatment with Dexamethasone (Dex), a synthetic glucocorticoid and multi-purpose anti-inflammatory drug. However, as glucocor...
Source: Proteomics - February 29, 2024 Category: Biochemistry Authors: Youli K. Stepanov, Carola Herrmann, Jan B. St öckl, Frank‐Michael Köhn, Ulrich Pickl, Mathias Trottmann, Thomas Fröhlich, Artur Mayerhofer, Harald Welter Tags: DATASET BRIEF Source Type: research