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Microproteins —Discovery, structure, and function
AbstractAdvances in proteogenomic technologies have revealed hundreds to thousands of translated small open reading frames (sORFs) that encode microproteins in genomes across evolutionary space. While many microproteins have now been shown to play critical roles in biology and human disease, a majority of recently identified microproteins have little or no experimental evidence regarding their functionality. Computational tools have some limitations for analysis of short, poorly conserved microprotein sequences, so additional approaches are needed to determine the role of each member of this recently discovered polypeptide...
Source: Proteomics - August 22, 2023 Category: Biochemistry Authors: Jessica J. Mohsen, Alina A. Martel, Sarah A. Slavoff Tags: REVIEW Source Type: research

Front Cover
Cover Image © Wiley-VCH GmbH. The image is part of a figure in the article DOI:10.1002/pmic.201900203 by Lei Li, Yong Jiang et al. (Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: FRONT COVER Source Type: research

Contents: Proteomics 16'23
(Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: CONTENTS Source Type: research