Standard abbreviations
(Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: STANDARD ABBREVIATIONS Source Type: research

Front Cover
Cover Image © Wiley-VCH GmbH. The image is part of a figure in the article DOI:10.1002/pmic.201900203 by Lei Li, Yong Jiang et al. (Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: FRONT COVER Source Type: research

Contents: Proteomics 16'23
(Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: CONTENTS Source Type: research

Editorial Board: Proteomics 16'23
(Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: EDITORIAL BOARD Source Type: research

Standard abbreviations
(Source: Proteomics)
Source: Proteomics - August 11, 2023 Category: Biochemistry Tags: STANDARD ABBREVIATIONS Source Type: research

GeLC ‐FAIMS‐MS workflow for in‐depth middle‐down proteomics
In this study, we applied GeLC-FAIMS-MS, a multidimensional separation w orkflow that combines gel-based prefractionation with LC-FAIMS MS, for deep MDP. Middle-down peptides generated by optimized limited Glu-C digestion conditions were first size-fractionated by polyacrylamide gel electrophoresis, followed by C4 reversed-phase liquid chromatography separation and addit ional ion mobility fractionation, resulting in a significant increase in peptide length detectable by MS. In addition to global analysis, the GeLC-FAIMS-MS concept can also be applied to targeted MDP, where only proteins in the desired molecular weight ran...
Source: Proteomics - August 8, 2023 Category: Biochemistry Authors: Ayako Takemori, Philipp T. Kaulich, Ryo Konno, Yusuke Kawashima, Yuto Hamazaki, Ayuko Hoshino, Andreas Tholey, Nobuaki Takemori Tags: RESEARCH ARTICLE Source Type: research

Evaluation of protein extraction methods to improve meta ‐proteomics analysis of treated wastewater biofilms
This study provides the first insight into evaluating protein extraction methods to facilitate metaproteomics for complex reclaimed water matrices. (Source: Proteomics)
Source: Proteomics - August 5, 2023 Category: Biochemistry Authors: Fatimah Almulhim, Pei ‐Ying Hong Tags: TECHNICAL BRIEF Source Type: research

A top ‐down proteomic approach reveals a salivary protein profile able to classify Parkinson's disease with respect to Alzheimer's disease patients and to healthy controls
AbstractParkinson's disease (PD) is a complex neurodegenerative disease with motor and non-motor symptoms. Diagnosis is complicated by lack of reliable biomarkers. To individuate peptides and/or proteins with diagnostic potential for early diagnosis, severity and discrimination from similar pathologies, the salivary proteome in 36 PD patients was investigated in comparison with 36 healthy controls (HC) and 35 Alzheimer's disease (AD) patients. A top-down platform based on HPLC-ESI-IT-MS allowed characterizing and quantifying intact peptides, small proteins and their PTMs (overall 51). The three groups showed significantly ...
Source: Proteomics - August 4, 2023 Category: Biochemistry Authors: Cristina Contini, Laura Fadda, Greca Lai, Carla Masala, Alessandra Olianas, Massimo Castagnola, Irene Messana, Federica Iavarone, Alessandra Bizzarro, Carlo Masullo, Paolo Solla, Giovanni Defazio, Barbara Manconi, Giacomo Diaz, Tiziana Cabra Tags: RESEARCH ARTICLE Source Type: research

Proteome of urticating setae of Ochrogaster lunifer, a processionary caterpillar of medical and veterinary importance, including primary structures of putative toxins
AbstractOchrogaster lunifer (Lepidoptera: Notodontidae) is an Australian processionary caterpillar with detachable urticating setae that have a defensive function. These true setae induce inflammation when they contact human skin, and equine foetal loss syndrome if they are accidentally ingested by gravid horses. We used transcriptomics and proteomics to identify proteins and peptides present in and on urticating setae, which may include toxins that contribute to inflammation and/or foetal loss syndromes. This process identified 37 putative toxins, including multiple homologues of the honeybee venom peptide secapin, and pr...
Source: Proteomics - August 2, 2023 Category: Biochemistry Authors: Andrew A. Walker, Lynda E. Perkins, Andrea Battisti, Myron P. Zalucki, Glenn F. King Tags: RESEARCH ARTICLE Source Type: research

Front Cover
Cover Image © Wiley-VCH GmbH. The image is part of a figure in the article DOI:10.1002/pmic.201900203 by Lei Li, Yong Jiang et al. (Source: Proteomics)
Source: Proteomics - August 1, 2023 Category: Biochemistry Tags: FRONT COVER Source Type: research

Contents: Proteomics 15'23
(Source: Proteomics)
Source: Proteomics - August 1, 2023 Category: Biochemistry Tags: CONTENTS Source Type: research