Cardiac Hypertrophy Associated with Insulin Therapy in Extremely Preterm Infants
CONCLUSIONS: Our case series supports the association between the development of CH and insulin therapy in extremely preterm infants and suggests further caution and the need for echocardiographic monitoring when treating these fragile patients with insulin.PMID:37204612 | DOI:10.1007/s40272-023-00571-0 (Source: Paediatric Drugs)
Source: Paediatric Drugs - May 19, 2023 Category: Pediatrics Authors: Carlo Dani Michele Luzzati Iuri Corsini Chiara Poggi Venturella Vangi Caterina Coviello Simone Pratesi Source Type: research
Pediatric Status Epilepticus: Treat Early and Avoid Delays
Paediatr Drugs. 2023 May 13. doi: 10.1007/s40272-023-00570-1. Online ahead of print.ABSTRACTPediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early treatment, cessation of out-of-hospital SE is undermined by treatment delay and inadequate dosing. Logistical challenges include prompt seizure recognition, first-line benzodiazepine (BZD) availability, comfort and expertise in...
Source: Paediatric Drugs - May 13, 2023 Category: Pediatrics Authors: Lindsey A Morgan Jennifer B Hrachovec Howard P Goodkin Source Type: research
Pediatric Status Epilepticus: Treat Early and Avoid Delays
Paediatr Drugs. 2023 May 13. doi: 10.1007/s40272-023-00570-1. Online ahead of print.ABSTRACTPediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early treatment, cessation of out-of-hospital SE is undermined by treatment delay and inadequate dosing. Logistical challenges include prompt seizure recognition, first-line benzodiazepine (BZD) availability, comfort and expertise in...
Source: Paediatric Drugs - May 13, 2023 Category: Pediatrics Authors: Lindsey A Morgan Jennifer B Hrachovec Howard P Goodkin Source Type: research
Pediatric Status Epilepticus: Treat Early and Avoid Delays
Paediatr Drugs. 2023 May 13. doi: 10.1007/s40272-023-00570-1. Online ahead of print.ABSTRACTPediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early treatment, cessation of out-of-hospital SE is undermined by treatment delay and inadequate dosing. Logistical challenges include prompt seizure recognition, first-line benzodiazepine (BZD) availability, comfort and expertise in...
Source: Paediatric Drugs - May 13, 2023 Category: Pediatrics Authors: Lindsey A Morgan Jennifer B Hrachovec Howard P Goodkin Source Type: research
Pediatric Status Epilepticus: Treat Early and Avoid Delays
Paediatr Drugs. 2023 May 13. doi: 10.1007/s40272-023-00570-1. Online ahead of print.ABSTRACTPediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early treatment, cessation of out-of-hospital SE is undermined by treatment delay and inadequate dosing. Logistical challenges include prompt seizure recognition, first-line benzodiazepine (BZD) availability, comfort and expertise in...
Source: Paediatric Drugs - May 13, 2023 Category: Pediatrics Authors: Lindsey A Morgan Jennifer B Hrachovec Howard P Goodkin Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4:1-10. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4:1-10. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4:1-10. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4:1-10. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have show...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have show...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have show...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Paediatr Drugs. 2023 May 4. doi: 10.1007/s40272-023-00566-x. Online ahead of print.ABSTRACTIn addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have show...
Source: Paediatric Drugs - May 4, 2023 Category: Pediatrics Authors: Hadi Sahrai Mahdi Hemmati-Ghavshough Marzieh Shahrabi Amir Hossein Jafari-Rouhi Mohammad Solduzian Source Type: research
Ewing Sarcoma Drug Therapy: Current Standard of Care and Emerging Agents
Paediatr Drugs. 2023 Apr 4. doi: 10.1007/s40272-023-00568-9. Online ahead of print.ABSTRACTEwing sarcoma is a translocation-associated sarcoma mainly impacting adolescents and young adults. The classic translocation (EWSR1::FLI1) leads to a fusion oncoprotein that functions as an aberrant transcription factor. As such, the oncogenic driver of this disease has been difficult to target pharmacologically and, therefore, the systemic therapies used to treat patients with Ewing sarcoma have typically been non-selective cytotoxic chemotherapy agents. The current review highlights recent clinical trials from the last decade that ...
Source: Paediatric Drugs - April 4, 2023 Category: Pediatrics Authors: Bhuvana A Setty Ajami Gikandi Steven G DuBois Source Type: research
Ewing Sarcoma Drug Therapy: Current Standard of Care and Emerging Agents
Paediatr Drugs. 2023 Apr 4. doi: 10.1007/s40272-023-00568-9. Online ahead of print.ABSTRACTEwing sarcoma is a translocation-associated sarcoma mainly impacting adolescents and young adults. The classic translocation (EWSR1::FLI1) leads to a fusion oncoprotein that functions as an aberrant transcription factor. As such, the oncogenic driver of this disease has been difficult to target pharmacologically and, therefore, the systemic therapies used to treat patients with Ewing sarcoma have typically been non-selective cytotoxic chemotherapy agents. The current review highlights recent clinical trials from the last decade that ...
Source: Paediatric Drugs - April 4, 2023 Category: Pediatrics Authors: Bhuvana A Setty Ajami Gikandi Steven G DuBois Source Type: research
