Nitric Oxide Is Locally Produced in the Human Middle Ear and Is Reduced by Acquired Cholesteatoma
Conclusions:
NO is likely a natural and permanent part of the gas mixture in the human middle ear. The presence of NOS enzymes in the middle ear mucosa indicates an ongoing NO production and the reduction of NOS in ears with cholesteatoma, and pooled samples from ears with COM, suggest a role for locally produced NO in middle ear disease. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Transeustachian Middle Ear Endoscopy Using a Steerable Distal-Camera Tipped Endoscope
Conclusions:
A steerable endoscope can be designed to traverse the human Eustachian tube and provide diagnostic quality images of middle ear anatomy. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Caregiver Quality of Life After Cochlear Implantation in Older Adults
Conclusions:
Higher QOL scores were found among caregivers of healthier, female CI recipients. Patient hearing measurements did not correspond with better caregiver QOL. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Implications of Phase Changes in Extracochlear Electrocochleographic Recordings During Cochlear Implantation
Conclusions:
Phase changes occur regularly in extracochlear ECochG recordings during cochlear implantation. Phase changes of ≥90° with or without amplitude changes in the ECochG signal are associated with a larger postoperative hearing loss and could therefore represent an independent marker for cochlear trauma or changes of inner ear mechanics relevant for the postoperative hearing outcome. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Accessing the Stapedius Muscle Via Novel Surgical Retrofacial Approach: A Cadaveric Feasibility Study
Conclusions:
The retrofacial approach seems to offer a feasible and reproducible access to the SM belly opening an avenue to electromyographic sensing of eSRT. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Use of Auditory Training and Its Influence on Early Cochlear Implant Outcomes in Adults
Conclusions:
Our findings provide preliminary evidence-based recommendations for use of specific auditory training resources for new adult CI recipients. Auditory training, especially self-directed computer software, resulted in improved speech recognition and CIQOL outcomes after 3 months and are widely available for CI users. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Intracochlear New Fibro-Ossification and Neuronal Degeneration Following Cochlear Implant Electrode Translocation: Long-Term Histopathological Findings in Humans
Conclusions:
Cochlear implant electrode translocation was associated with greater fibroosseous formation and lower SGN population. Our findings suggest that scalar translocations may slow the rate of improvement in WRS overtime as compared to atraumatic electrode insertions.
Level of evidence: IV. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Automated Calculation of Cochlear Implant Electrode Insertion Parameters in Clinical Cone-Beam CT
Conclusion:
Automated processing of implanted high-resolution CBCT images can provide the clinician with key information on electrode placement. This is one step toward routine use of clinical CBCT after CI surgery to inform and guide postoperative treatment. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Augmented Reality Based Transmodiolar Cochlear Implantation
Conclusion:
We developed an image-based ARS to identify the extremities and the axis of the cochlear modiolus on intraprocedure videos. The system yielded submillimetric accuracy for implantation and remained stable throughout the experimental study. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Insertion Depth and Cochlear Implant Speech Recognition Outcomes: A Comparative Study of 28- and 31.5-mm Lateral Wall Arrays
Objectives:
1) To compare speech recognition outcomes between cochlear implant (CI) recipients of 28- and 31.5-mm lateral wall electrode arrays, and 2) to characterize the relationship between angular insertion depth (AID) and speech recognition.
Study Design:
Retrospective review.
Setting:
Tertiary academic referral center.
Patients:
Seventy-five adult CI recipients of fully inserted 28-mm (n = 28) or 31.5-mm (n = 47) lateral wall arrays listening with a CI-alone device.
Interventions:
Cochlear implantation with postoperative computed tomography.
Main Outcome Measures:
Conson...
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Measurement and Mitigation of Intracochlear Pressure Transients During Cochlear Implant Electrode Insertion
Hypothesis:
High intracochlear pressure transients associated with cochlear implant placement are reduced with smaller, non-styleted arrays, and longer insertion durations.
Background:
With increasing focus on hearing preservation during cochlear implant surgery, atraumatic technique is of the utmost importance. Previous studies revealed that high intensity pressure transients can be generated during the insertion of implant electrodes. Resulting acoustic trauma may be one contributing factor to postoperative loss of residual hearing.
Methods:
Thirty ears in cadaveric specimens were surgically prepared wi...
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Sensorineural Hearing Loss After Teprotumumab Therapy for Thyroid Eye Disease: A Case Report
Conclusions:
There are currently no formal guidelines for routine audiograms before, during, and after infusion of teprotumumab. Given that such guidelines exist for ototoxic medications such as gentamicin and cisplatin, we strongly encourage audiometric monitoring for patients undergoing treatment with teprotumumab. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: SENSORINEURAL HEARING LOSS AND TINNITUS Source Type: research
Calcium Channel Blockers and the Risk of Sensorineural Hearing Loss
Conclusion:
This analysis found evidence supporting the theory that calcium channel blockers might be a potential prophylactic agent for sensorineural hearing loss. Additional research is warranted. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: SENSORINEURAL HEARING LOSS AND TINNITUS Source Type: research
No COVID-19 in Patients With Sudden Sensorineural Hearing Loss (SSNHL)
Conclusions:
This is the largest series to date investigating COVID-19 in SSNHL patients. In this series there is no apparent relationship between SSNHL and COVID-19. (Source: Otology and Neurotology)
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: SENSORINEURAL HEARING LOSS AND TINNITUS Source Type: research
Outcomes of Stapedotomy in Patients With Concomitant Otosclerosis and Superior Semicircular Canal Dehiscence: Should a Radiographic Third-Window Be a Contraindication to Stapes Surgery?
Objective:
Review surgical outcomes of stapedotomy in patients with concomitant otosclerosis and superior semicircular canal dehiscence.
Study design:
Retrospective case review.
Setting:
Tertiary referral center.
Patients:
Patients with otosclerosis and radiographic superior semicircular canal dehiscence undergoing stapedotomy between 2008 and 2020.
Intervention:
Stapedotomy.
Main outcome measures:
Pre- and postoperative hearing and unmasking of third-window symptoms. Hearing was measured by air conduction (AC) and bone conduction (BC) pure-tone averages (PTA), air-bone gap (ABG), and...
Source: Otology and Neurotology - January 16, 2022 Category: ENT & OMF Tags: OTOSCLEROSIS Source Type: research
