Mesenchymal Stem Cells for Treatment of Delayed-Healing Tympanic Membrane Perforations Using Hyaluronate-based Laminas as a Delivery System: An Animal Model With Histopathologic Study
Conclusions:
BM-MSCs and cell culture media equivalently increased cTMP healing rates. Cell-based therapy conferred a restoration of the trilaminar configuration of the eardrum with relatively compact and organized fibrous layers. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: BASIC SCIENCE Source Type: research
Intraoperative Use of Electrical Stapedius Reflex Testing for Cochlear Nerve Monitoring During Simultaneous Translabyrinthine Resection of Vestibular Schwannoma and Cochlear Implantation
Conclusion:
The current study demonstrates the feasibility of using intraoperative eSR via a CI electrode to monitor cochlear nerve integrity during VS resection, which may indicate successful CI outcomes. These preliminary findings require further substantiation in a larger study. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: TUMORS OF THE EAR AND CRANIAL BASE Source Type: research
Comparison of Outcomes of Surgical Repair of Spontaneous Temporal Bone CSF Leaks and Encephaloceles Using Bone Cement and Autologous Material
Objective:
To compare outcomes transmastoid repair of spontaneous middle fossa cerebrospinal fluid (CSF) leak using only bone cement (BC) versus only autologous material (AM) or combined materials (CM) with both bone cement and autologous material.
Study Design:
Retrospective Chart Review.
Setting:
Tertiary Care Hospital.
Patients:
Forty-three adult patients undergoing transmastoid repair of spontaneous middle fossa CSF leak between 2014 and 2020 (BC:12, AM:15, CR:16).
Interventions:
Cortical mastoidectomy, identification of defect, and repair with BC (Cranios® hydroxyapatite), AM (local bo...
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: TUMORS OF THE EAR AND CRANIAL BASE Source Type: research
A Portrait of Menière's Disease Using Contemporary Hearing and Balance Tests
Conclusion:
Menière's disease has a distinctive history, but atypical presentations with normal vestibular function and hearing are a diagnostic challenge delaying treatment initiation. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: VESTIBULAR DISORDERS Source Type: research
Dizziness Symptoms, Balance Confidence, and Vestibular Function in Older Women Reporting Dizziness and Unsteadiness
Conclusion:
Women reporting higher levels of distress due to dizziness had reduced walking speed and reported less balance confidence and higher levels of anxiety and depression. The findings support the theory that DHI captures aspects of overall self-rated wellbeing and function rather than structural vestibular deficits. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: VESTIBULAR DISORDERS Source Type: research
Long-term Prognosis of Vertigo Attacks and Health-related Quality of Life Limitations in Patients With Vestibular Paroxysmia
Conclusion:
Our study shows a rather unfavorable prognosis in patients with VP in terms of vertigo attacks and HRQoL limitations. After the initial diagnosis follow-up is warranted to monitor clinical outcomes in these patients. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: VESTIBULAR DISORDERS Source Type: research
Predictive Factors for Concurrent Tegmen Dehiscence in Superior Canal Dehiscence Syndrome
Conclusions:
Obesity, OSA, preoperative oVEMP, and LF-ABG do not differ between those with SCD alone and those with SCD and concurrent tegmen dehiscences. Likewise, CT scans have relatively low sensitivity for identifying tegmen dehiscences. The presence of concurrent tegmen defects is more common in subjects with larger SCD cross-sectional areas and contralateral SCD. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: VESTIBULAR DISORDERS Source Type: research
Endolymphatic Hydrops Magnetic Resonance Imaging in Menire's Disease Patients on a Vertigo Attack
Conclusion:
MRI with intravenous gadolinium injection can provide a better assessment of EH in MD patient on a vertigo attack. Vestibular EH seems to be closely related with the vertigo attacks in MD patients, which needs further study. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: VESTIBULAR DISORDERS Source Type: research
An Artificial Intelligence Computer-vision Algorithm to Triage Otoscopic Images From Australian Aboriginal and Torres Strait Islander Children
Conclusions:
The paucity of access to tertiary otolaryngology care for rural and remote Aboriginal and Torres Strait Islander communities may contribute to an under-identification of ear disease. Computer vision image classification algorithms can accurately classify ear disease from otoscopic images of Indigenous Australian children. In the future, a validated algorithm may integrate with existing telemedicine initiatives to support effective triage and facilitate early treatment and referral. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: PEDIATRIC OTOLOGY Source Type: research
Optical Clearing Agents for Optical Imaging Through Cartilage Tympanoplasties: A Preclinical Feasibility Study
Conclusions:
Optical clearing agents offer a potential pathway towards optical coherence tomography imaging of the middle ear in post-surgical ears with cartilage grafts. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Developmental Disruptions of the Human Stapes
Conclusions:
Malformations of the human stapes follow consistent patterns of early or late disruptions of the stapes subunits of mesodermal and/or neural crest origin. While the molecular events, including temporal coordination, that lead to a normally formed stapes are not yet fully understood, the observed patterns of human stapes malformation can be consistently classified into one of four patterns of developmental disruption. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Anatomical Variations of the Epitympanum and the Usable Space for Middle Ear Implants Analyzed With CT-assisted Imaging Using a Tablet-based Software
Conclusion:
The reported descriptive data regarding the anatomy of the epitympanum emphasizes the importance of preoperative planning, especially since the height of the epitympanum showed great interindividual variance potentially limiting implantation of AMEIs. The herein used tablet-based software seems to be convenient for preoperative assessment of individual anatomy in the hand of otosurgeons. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Enlargement of Eustachian Tube Lumen in Patulous Eustachian Tube Patients Compared to that by Aging
Conclusion:
The lumen of the ET is enlarged in both PET and aging. However, the responsible site was found to be different. While the enlargement of the ET lumen in 60 years and above subjects without PET mainly occurred near the pharyngeal orifice of the ET, it was near the isthmus in under 60 years PET patients. Further study of possible clinical implications of these findings as well as treatment strategy are required. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Patulous Eustachian Tube Patients With Oculopharyngeal Muscular Dystrophy
Conclusions:
It is important to consider PET or patent ET conditions when OPMD patients describe aural symptoms. (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
Myeloid Sarcoma of the Temporal Bone: A Unique Cause of Hearing Loss, Otalgia, and Facial Nerve Weakness
Conclusions:
Although myeloid sarcomas are exceedingly rare, it is necessary to consider them as part of the differential diagnosis for patients who might present with middle ear and mastoid opacification on computed tomography (CT) scan, hearing loss, otalgia, and facial nerve palsy. Physicians should maintain a high degree of suspicion in patients with a history of acute myelogenous leukemia (AML), especially if previous cytogenetic analysis revealed a t(8;21). (Source: Otology and Neurotology)
Source: Otology and Neurotology - March 16, 2022 Category: ENT & OMF Tags: MIDDLE EAR AND MASTOID DISEASE Source Type: research
