Metabolic dysfunction and obesity-related cancer: Beyond obesity and metabolic syndrome
CONCLUSION: Metabolic dysfunction is a key risk factor for obesity-related cancer, regardless of obesity status. Nonetheless, a harmonized definition of metabolic dysfunction will further clarify the magnitude of the relationship across cancer types, enable better comparisons across studies, and further guide criteria for obesity-related cancer risk stratification.PMID:35785479 | DOI:10.1002/oby.23444 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Prasoona Karra Maci Winn Svenja Pauleck Alicja Bulsiewicz-Jacobsen Lacie Peterson Adriana Coletta Jennifer Doherty Cornelia M Ulrich Scott A Summers Marc Gunter Sheetal Hardikar Mary C Playdon Source Type: research

Reversal of obesity development in Ceacam1 < sup > -/- < /sup > male mice by bone marrow transplantation or introduction of the human CEACAM1 gene
CONCLUSIONS: CEACAM1 expression in both the liver and immune cells regulates obesity and lipid storage pathways in the liver. Bone marrow reconstitution of the immune system or introduction of the human CEACAM1 gene can fully or partially reverse the phenotype.PMID:35785480 | DOI:10.1002/oby.23457 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Zhifang Zhang Deirdre La Placa Gabriel Gugiu Alyssa Thunen Keith Le John E Shively Source Type: research

Maternal free fatty acid concentration during pregnancy is associated with newborn hypothalamic microstructure in humans
CONCLUSIONS: These findings suggest that maternal overnutrition during pregnancy may influence the development of the fetal hypothalamus, which, in turn, may have clinical relevance for childhood obesity risk.PMID:35785481 | DOI:10.1002/oby.23452 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Jerod M Rasmussen Paul M Thompson Lauren E Gyllenhammer Karen L Lindsay Thomas G O'Connor Berthold Koletzko Sonja Entringer Pathik D Wadhwa Claudia Buss Source Type: research

Weight-change trajectory in relation to cancer risk: findings from a nationwide cohort study in South Korea
CONCLUSIONS: Maintaining weight and avoiding weight gain are crucial for reducing cancer risk, but achieving a stable, normal BMI optimizes cancer prevention.PMID:35785482 | DOI:10.1002/oby.23464 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Thi Phuong Thao Tran Ngoc Minh Luu Thi Tra Bui Minji Han Min Kyung Lim Jin-Kyoung Oh Source Type: research

Meet your editorial team
Obesity (Silver Spring). 2022 Jul;30(7):1319-1320. doi: 10.1002/oby.23504.NO ABSTRACTPMID:35785483 | DOI:10.1002/oby.23504 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Source Type: research

Nutrition for precision health: The time is now
Obesity (Silver Spring). 2022 Jul;30(7):1335-1344. doi: 10.1002/oby.23448.ABSTRACTPrecision nutrition has emerged as a boiling area of nutrition research, with a particular focus on revealing the individual variability in response to diets that is determined mainly by the complex interactions of dietary factors with the multi-tiered "omics" makeups. Reproducible findings from the observational studies and diet intervention trials have lent preliminary but consistent evidence to support the fundamental role of gene-diet interactions in determining the individual variability in health outcomes including obesity and weight lo...
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Lu Qi Source Type: research

Ethnic disparities in liver fat accumulation in school-aged children
CONCLUSIONS: Prevalence of liver fat accumulation and NAFLD differs between ethnic subgroups living in the Netherlands, especially for those with a Turkish background. Early-life factors have a strong influence on these associations and may hold clues for future preventive strategies.PMID:35785476 | DOI:10.1002/oby.23478 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Jasmin M de Groot Madelon L Geurtsen Susana Santos Vincent W V Jaddoe Source Type: research

A randomized diet-induced weight-loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction
CONCLUSIONS: Diet-induced weight loss in men with abdominal obesity could be a way to lower plasma C3 and thereby improve endothelial dysfunction. C3 reduction may be part of the mechanism via which diet-induced weight loss could ameliorate the risk of cardiovascular disease in men with abdominal obesity.PMID:35785477 | DOI:10.1002/oby.23467 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Shunxin Jin Yvo H A M Kusters Alfons J H M Houben Jogchum Plat Peter J Joris Ronald P Mensink Casper G Schalkwijk Coen D A Stehouwer Marleen M J van Greevenbroek Source Type: research

Oligofructose restores postprandial short-chain fatty acid levels during high-fat feeding
CONCLUSIONS: The current study demonstrates that obesity is associated with reduced SCFA production, and that OFS supplementation increases SCFA levels. Additionally, postprandial butyrate production appears to be beneficial to host energy homeostasis.PMID:35785478 | PMC:PMC9260920 | DOI:10.1002/oby.23456 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Rachel K Meyer Adelina I Lane Savanna N Weninger Taylor M Martinez Archana Kangath Daniel Laubitz Frank A Duca Source Type: research

Metabolic dysfunction and obesity-related cancer: Beyond obesity and metabolic syndrome
CONCLUSION: Metabolic dysfunction is a key risk factor for obesity-related cancer, regardless of obesity status. Nonetheless, a harmonized definition of metabolic dysfunction will further clarify the magnitude of the relationship across cancer types, enable better comparisons across studies, and further guide criteria for obesity-related cancer risk stratification.PMID:35785479 | DOI:10.1002/oby.23444 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Prasoona Karra Maci Winn Svenja Pauleck Alicja Bulsiewicz-Jacobsen Lacie Peterson Adriana Coletta Jennifer Doherty Cornelia M Ulrich Scott A Summers Marc Gunter Sheetal Hardikar Mary C Playdon Source Type: research

Reversal of obesity development in Ceacam1 < sup > -/- < /sup > male mice by bone marrow transplantation or introduction of the human CEACAM1 gene
CONCLUSIONS: CEACAM1 expression in both the liver and immune cells regulates obesity and lipid storage pathways in the liver. Bone marrow reconstitution of the immune system or introduction of the human CEACAM1 gene can fully or partially reverse the phenotype.PMID:35785480 | DOI:10.1002/oby.23457 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Zhifang Zhang Deirdre La Placa Gabriel Gugiu Alyssa Thunen Keith Le John E Shively Source Type: research

Maternal free fatty acid concentration during pregnancy is associated with newborn hypothalamic microstructure in humans
CONCLUSIONS: These findings suggest that maternal overnutrition during pregnancy may influence the development of the fetal hypothalamus, which, in turn, may have clinical relevance for childhood obesity risk.PMID:35785481 | DOI:10.1002/oby.23452 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Jerod M Rasmussen Paul M Thompson Lauren E Gyllenhammer Karen L Lindsay Thomas G O'Connor Berthold Koletzko Sonja Entringer Pathik D Wadhwa Claudia Buss Source Type: research

Weight-change trajectory in relation to cancer risk: findings from a nationwide cohort study in South Korea
CONCLUSIONS: Maintaining weight and avoiding weight gain are crucial for reducing cancer risk, but achieving a stable, normal BMI optimizes cancer prevention.PMID:35785482 | DOI:10.1002/oby.23464 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Thi Phuong Thao Tran Ngoc Minh Luu Thi Tra Bui Minji Han Min Kyung Lim Jin-Kyoung Oh Source Type: research

Meet your editorial team
Obesity (Silver Spring). 2022 Jul;30(7):1319-1320. doi: 10.1002/oby.23504.NO ABSTRACTPMID:35785483 | DOI:10.1002/oby.23504 (Source: Obesity)
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Source Type: research

Nutrition for precision health: The time is now
Obesity (Silver Spring). 2022 Jul;30(7):1335-1344. doi: 10.1002/oby.23448.ABSTRACTPrecision nutrition has emerged as a boiling area of nutrition research, with a particular focus on revealing the individual variability in response to diets that is determined mainly by the complex interactions of dietary factors with the multi-tiered "omics" makeups. Reproducible findings from the observational studies and diet intervention trials have lent preliminary but consistent evidence to support the fundamental role of gene-diet interactions in determining the individual variability in health outcomes including obesity and weight lo...
Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Lu Qi Source Type: research