Phenotyping children and adolescents with obesity using behavioral, psychological, and familial data
CONCLUSIONS: These results support examining risk factors for and treatment outcomes by obesity phenotypes.PMID:37987184 | DOI:10.1002/oby.23893 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Ruth G St Fleur Marian Tanofsky-Kraff Jack A Yanovski Nicholas J Horton Joel N Hirschhorn Alison E Field Source Type: research

One-anastomosis gastric bypass versus Roux-en-Y gastric bypass: The evidence wins
Obesity (Silver Spring). 2023 Dec;31(12):2891-2892. doi: 10.1002/oby.23909.NO ABSTRACTPMID:37987185 | DOI:10.1002/oby.23909 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Ricardo V Cohen Torsten Olbers Source Type: research

Combining diabetes, sex, and menopause as meaningful clinical features associated with NASH and liver fibrosis in individuals with class II and III obesity: A retrospective cohort study
CONCLUSIONS: This study unveiled a remarkably high prevalence of advanced SLD after menopause in women with T2D, associated with a dysfunctional biological liver profile.PMID:37987186 | DOI:10.1002/oby.23904 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Violeta Raverdy Estelle Chatelain Guillaume Lasailly Robert Caiazzo Jimmy Vandel Helene Verkindt Camille Marciniak Benjamin Legendre Pierre Bauvin Naima Oukhouya-Daoud Gregory Baud Mikael Chetboun Marie-Christine Vantyghem Viviane Gnemmi Emmanuelle Leteur Source Type: research

Polygenic risk of obesity and BMI trajectories over 36  years: A longitudinal study of adult Finnish twins
CONCLUSIONS: Categorizing BMI as below, within, or above polygenic risk score-predicted BMI helps identifying individuals who have been resistant or susceptible to weight gain. This may provide new insights into determinants and consequences of obesity.PMID:37987187 | DOI:10.1002/oby.23906 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Bram J Berntzen Teemu Palviainen Karri Silventoinen Kirsi H Pietil äinen Jaakko Kaprio Source Type: research

Efficacy and safety of semaglutide 2.4  mg according to antidepressant use at baseline: A post hoc subgroup analysis
CONCLUSIONS: In adults with overweight/obesity, semaglutide provided clinically meaningful weight loss regardless of baseline AD use, with an AE profile consistent with previous studies.PMID:37989717 | DOI:10.1002/oby.23946 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Robert F Kushner Anders Fink-Jensen Ofir Frenkel Barbara McGowan Bryan Goldman Maria Overvad Thomas Wadden Source Type: research

Update on N6-methyladenosine methylation in obesity-related diseases
Obesity (Silver Spring). 2023 Nov 21. doi: 10.1002/oby.23932. Online ahead of print.ABSTRACTObesity is a chronic metabolic disease that is closely related to type 2 diabetes mellitus, cardiovascular diseases, nonalcoholic fatty liver disease, obstructive sleep apnea, and osteoarthritis. The prevalence of obesity is increasing rapidly every year and is recognized as a global public health problem. In recent years, the role of epigenetics in the development of obesity and related diseases has been recognized and is currently a research hotspot. N6-methyladenosine (m6A) methylation is the most abundant epigenetic modification...
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Caiqin Cheng Fan Yu Guoyue Yuan Jue Jia Source Type: research

Roux-en-Y versus one-anastomosis gastric bypass (RYSA study): weight loss, metabolic improvements, and nutrition at 1  year after surgery, a multicenter randomized controlled trial
CONCLUSIONS: RYGB and OAGB were comparable in weight loss, metabolic improvement, remission of diabetes and hypercholesterolemia, and nutrition at 1-year follow-up. Vitamin D-25 deficiency was more prevalent with OAGB, whereas reduction in antihypertensive medications and hypertension was greater with RYGB. There is no need to change the current practices of RYGB in favor of OAGB.PMID:37987183 | DOI:10.1002/oby.23852 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Sini Heinonen Tuure Saarinen Sanna Meril äinen Henna Sammalkorpi Anne K Penttil ä Minna Koivikko Pertti Siira Jaro Karppinen Ulla S äiläkivi Milla Roseng ård-Bärlund Vesa Koivukangas Kirsi H Pietil äinen Anne Juuti Source Type: research

Phenotyping children and adolescents with obesity using behavioral, psychological, and familial data
CONCLUSIONS: These results support examining risk factors for and treatment outcomes by obesity phenotypes.PMID:37987184 | DOI:10.1002/oby.23893 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Ruth G St Fleur Marian Tanofsky-Kraff Jack A Yanovski Nicholas J Horton Joel N Hirschhorn Alison E Field Source Type: research

One-anastomosis gastric bypass versus Roux-en-Y gastric bypass: The evidence wins
Obesity (Silver Spring). 2023 Dec;31(12):2891-2892. doi: 10.1002/oby.23909.NO ABSTRACTPMID:37987185 | DOI:10.1002/oby.23909 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Ricardo V Cohen Torsten Olbers Source Type: research

Combining diabetes, sex, and menopause as meaningful clinical features associated with NASH and liver fibrosis in individuals with class II and III obesity: A retrospective cohort study
CONCLUSIONS: This study unveiled a remarkably high prevalence of advanced SLD after menopause in women with T2D, associated with a dysfunctional biological liver profile.PMID:37987186 | DOI:10.1002/oby.23904 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Violeta Raverdy Estelle Chatelain Guillaume Lasailly Robert Caiazzo Jimmy Vandel Helene Verkindt Camille Marciniak Benjamin Legendre Pierre Bauvin Naima Oukhouya-Daoud Gregory Baud Mikael Chetboun Marie-Christine Vantyghem Viviane Gnemmi Emmanuelle Leteur Source Type: research

Polygenic risk of obesity and BMI trajectories over 36  years: A longitudinal study of adult Finnish twins
CONCLUSIONS: Categorizing BMI as below, within, or above polygenic risk score-predicted BMI helps identifying individuals who have been resistant or susceptible to weight gain. This may provide new insights into determinants and consequences of obesity.PMID:37987187 | DOI:10.1002/oby.23906 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Bram J Berntzen Teemu Palviainen Karri Silventoinen Kirsi H Pietil äinen Jaakko Kaprio Source Type: research

Efficacy and safety of semaglutide 2.4  mg according to antidepressant use at baseline: A post hoc subgroup analysis
CONCLUSIONS: In adults with overweight/obesity, semaglutide provided clinically meaningful weight loss regardless of baseline AD use, with an AE profile consistent with previous studies.PMID:37989717 | DOI:10.1002/oby.23946 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Robert F Kushner Anders Fink-Jensen Ofir Frenkel Barbara McGowan Bryan Goldman Maria Overvad Thomas Wadden Source Type: research

Update on N6-methyladenosine methylation in obesity-related diseases
Obesity (Silver Spring). 2023 Nov 21. doi: 10.1002/oby.23932. Online ahead of print.ABSTRACTObesity is a chronic metabolic disease that is closely related to type 2 diabetes mellitus, cardiovascular diseases, nonalcoholic fatty liver disease, obstructive sleep apnea, and osteoarthritis. The prevalence of obesity is increasing rapidly every year and is recognized as a global public health problem. In recent years, the role of epigenetics in the development of obesity and related diseases has been recognized and is currently a research hotspot. N6-methyladenosine (m6A) methylation is the most abundant epigenetic modification...
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Caiqin Cheng Fan Yu Guoyue Yuan Jue Jia Source Type: research

Roux-en-Y versus one-anastomosis gastric bypass (RYSA study): weight loss, metabolic improvements, and nutrition at 1  year after surgery, a multicenter randomized controlled trial
CONCLUSIONS: RYGB and OAGB were comparable in weight loss, metabolic improvement, remission of diabetes and hypercholesterolemia, and nutrition at 1-year follow-up. Vitamin D-25 deficiency was more prevalent with OAGB, whereas reduction in antihypertensive medications and hypertension was greater with RYGB. There is no need to change the current practices of RYGB in favor of OAGB.PMID:37987183 | DOI:10.1002/oby.23852 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Sini Heinonen Tuure Saarinen Sanna Meril äinen Henna Sammalkorpi Anne K Penttil ä Minna Koivikko Pertti Siira Jaro Karppinen Ulla S äiläkivi Milla Roseng ård-Bärlund Vesa Koivukangas Kirsi H Pietil äinen Anne Juuti Source Type: research

Phenotyping children and adolescents with obesity using behavioral, psychological, and familial data
CONCLUSIONS: These results support examining risk factors for and treatment outcomes by obesity phenotypes.PMID:37987184 | DOI:10.1002/oby.23893 (Source: Obesity)
Source: Obesity - November 21, 2023 Category: Eating Disorders & Weight Management Authors: Ruth G St Fleur Marian Tanofsky-Kraff Jack A Yanovski Nicholas J Horton Joel N Hirschhorn Alison E Field Source Type: research