Obesity alters the circadian profiles of energy metabolism and glucose regulation in humans
CONCLUSIONS: Obesity is associated with altered circadian energy and glucose metabolism. Understanding and addressing these associations could lead to strategies that improve body weight and metabolic health in people with obesity.PMID:37964700 | DOI:10.1002/oby.23940 (Source: Obesity)
Source: Obesity - November 15, 2023 Category: Eating Disorders & Weight Management Authors: Andrew W McHill Saurabh S Thosar Nicole P Bowles Matthew P Butler Omar Ordaz-Johnson Jonathan S Emens Jonathan Q Purnell Melanie Gillingham Steven A Shea Source Type: research
Obesity alters the circadian profiles of energy metabolism and glucose regulation in humans
CONCLUSIONS: Obesity is associated with altered circadian energy and glucose metabolism. Understanding and addressing these associations could lead to strategies that improve body weight and metabolic health in people with obesity.PMID:37964700 | DOI:10.1002/oby.23940 (Source: Obesity)
Source: Obesity - November 15, 2023 Category: Eating Disorders & Weight Management Authors: Andrew W McHill Saurabh S Thosar Nicole P Bowles Matthew P Butler Omar Ordaz-Johnson Jonathan S Emens Jonathan Q Purnell Melanie Gillingham Steven A Shea Source Type: research
Metabolite signature of diabetes remission in individuals with obesity undergoing weight loss interventions
CONCLUSIONS: This study confirmed known metabolite associations with obesity/T2D and showed an association of BCAAs with HbA1c change after weight loss, independent of the method or magnitude of weight loss.PMID:37962326 | DOI:10.1002/oby.23943 (Source: Obesity)
Source: Obesity - November 14, 2023 Category: Eating Disorders & Weight Management Authors: Vidhu V Thaker Lydia Coulter Kwee Haiying Chen Judy Bahnson Olga Ilkayeva Michael J Muehlbauer Bruce Wolfe Jonathan Q Purnell Xavier Pi-Sunyer Christopher B Newgard Svati H Shah Blandine Laferr ère Look AHEAD Research Group Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Semaglutide 2.4 mg/wk for weight loss in patients with severe obesity and with or without a history of bariatric surgery
CONCLUSIONS: This study is the first, to the authors' knowledge, to compare the effectiveness of semaglutide treatment in patients with versus those without a history of BS, providing valuable evidence of its efficacy. By focusing on individuals with severe obesity (BMI > 40 kg/m2 and associated comorbidities), it fills a gap in the current literature and highlights the potential of semaglutide 2.4 mg as a treatment option for this specific population.PMID:37927153 | DOI:10.1002/oby.23922 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Jean-Baptiste Bonnet Sarah Tournayre Jean Anitcheou Marion Faivre Catherine Boegner Abdulkader Jalek Dominique Jullien Vincent Attalin Justine Myzia Lucile Marty Youadigue Kemba David Nocca Ariane Sultan Antoine Avignon Source Type: research
Observational and genetic associations of adiposity with cardiopulmonary multimorbidity: Linear and nonlinear Mendelian randomization analysis
CONCLUSIONS: Adiposity may play a causal role in CP-MM development and represent a promising approach for multimorbidity prevention.PMID:37927163 | DOI:10.1002/oby.23934 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Zimin Song Wenxiu Wang Yimin Zhao Wendi Xiao Jie Du Zhonghua Liu Tao Huang Yida Tang Source Type: research
Prevalence and variations in gastric emptying delay in response to GLP-1 receptor agonist liraglutide
Obesity (Silver Spring). 2023 Nov 5. doi: 10.1002/oby.23941. Online ahead of print.NO ABSTRACTPMID:37927173 | DOI:10.1002/oby.23941 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Michael Camilleri Paula Carlson Saam Dilmaghani Source Type: research
Effects of energy loads on energy and nutrient absorption rates and gut microbiome in humans: A randomized crossover trial
CONCLUSIONS: Although short-term overfeeding dynamically altered the gut microbiota composition, the energy excretion rate via feces was unaffected. Energy excretion rates via urine and urine plus feces were lower under OF than under CON and UF conditions.PMID:37927202 | DOI:10.1002/oby.23935 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Eiichi Yoshimura Yuka Hamada Yoichi Hatamoto Takashi Nakagata Hinako Nanri Yui Nakayama Takanori Hayashi Ippei Suzuki Takafumi Ando Kazuko Ishikawa-Takata Shigeho Tanaka Rei Ono Jonguk Park Koji Hosomi Kenji Mizuguchi Jun Kunisawa Motohiko Miyachi Source Type: research
Metabolic and structural remodeling during browning of primary human adipocytes derived from omental and subcutaneous depots
CONCLUSIONS: Metabolic and structural remodeling during browning of primary human adipocytes is similar to previous findings in human adipocytes in vivo, supporting their uses for mechanical studies investigating browning with translational relevance.PMID:37929774 | DOI:10.1002/oby.23912 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Mi-Jeong Lee Vishwajeet Puri Susan K Fried Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Semaglutide 2.4 mg/wk for weight loss in patients with severe obesity and with or without a history of bariatric surgery
CONCLUSIONS: This study is the first, to the authors' knowledge, to compare the effectiveness of semaglutide treatment in patients with versus those without a history of BS, providing valuable evidence of its efficacy. By focusing on individuals with severe obesity (BMI > 40 kg/m2 and associated comorbidities), it fills a gap in the current literature and highlights the potential of semaglutide 2.4 mg as a treatment option for this specific population.PMID:37927153 | DOI:10.1002/oby.23922 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Jean-Baptiste Bonnet Sarah Tournayre Jean Anitcheou Marion Faivre Catherine Boegner Abdulkader Jalek Dominique Jullien Vincent Attalin Justine Myzia Lucile Marty Youadigue Kemba David Nocca Ariane Sultan Antoine Avignon Source Type: research
Observational and genetic associations of adiposity with cardiopulmonary multimorbidity: Linear and nonlinear Mendelian randomization analysis
CONCLUSIONS: Adiposity may play a causal role in CP-MM development and represent a promising approach for multimorbidity prevention.PMID:37927163 | DOI:10.1002/oby.23934 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Zimin Song Wenxiu Wang Yimin Zhao Wendi Xiao Jie Du Zhonghua Liu Tao Huang Yida Tang Source Type: research
Prevalence and variations in gastric emptying delay in response to GLP-1 receptor agonist liraglutide
Obesity (Silver Spring). 2023 Nov 5. doi: 10.1002/oby.23941. Online ahead of print.NO ABSTRACTPMID:37927173 | DOI:10.1002/oby.23941 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Michael Camilleri Paula Carlson Saam Dilmaghani Source Type: research
Effects of energy loads on energy and nutrient absorption rates and gut microbiome in humans: A randomized crossover trial
CONCLUSIONS: Although short-term overfeeding dynamically altered the gut microbiota composition, the energy excretion rate via feces was unaffected. Energy excretion rates via urine and urine plus feces were lower under OF than under CON and UF conditions.PMID:37927202 | DOI:10.1002/oby.23935 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Eiichi Yoshimura Yuka Hamada Yoichi Hatamoto Takashi Nakagata Hinako Nanri Yui Nakayama Takanori Hayashi Ippei Suzuki Takafumi Ando Kazuko Ishikawa-Takata Shigeho Tanaka Rei Ono Jonguk Park Koji Hosomi Kenji Mizuguchi Jun Kunisawa Motohiko Miyachi Source Type: research
Metabolic and structural remodeling during browning of primary human adipocytes derived from omental and subcutaneous depots
CONCLUSIONS: Metabolic and structural remodeling during browning of primary human adipocytes is similar to previous findings in human adipocytes in vivo, supporting their uses for mechanical studies investigating browning with translational relevance.PMID:37929774 | DOI:10.1002/oby.23912 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Mi-Jeong Lee Vishwajeet Puri Susan K Fried Source Type: research
