Advances and Ongoing Controversies in Patent Foramen Ovale Closure and Cryptogenic Stroke
Up to a third of strokes are cryptogenic. The prevalence of patent foramen ovale (PFO) in patients with cryptogenic stroke is higher than in individuals with stroke of known origin. It has been proposed that some cryptogenic strokes can be caused by paradoxic embolism across a PFO. The treatment of PFO includes medical treatment with antithrombotic agents and percutaneous PFO closure. There is limited evidence to support PFO closure in unselected cases of cryptogenic stroke. However, large randomized clinical trials confirmed the superiority of transcatheter PFO closure compared with medical treatment in young patients wit...
Source: Neurologic Clinics - November 7, 2020 Category: Neurology Authors: Joaquin B. Gonzalez, Fernando D. Testai Source Type: research
An Update on Botulinum Toxin in Neurology
This article gives a comprehensive overview of the clinical applications of BoNT across the field of neurology. (Source: Neurologic Clinics)
Source: Neurologic Clinics - November 7, 2020 Category: Neurology Authors: Shannon Y. Chiu, Matthew R. Burns, Irene A. Malaty Source Type: research
Therapeutic Pitfalls in the Transition of Neurologic Patients from Pediatric to Adult Health Care Providers
Transitions of care from the pediatric to adult setting are fraught with difficulty. For patients whose neurologic problems began in childhood, there is often a lack of organized multidisciplinary care with the desired neurologic expertise in the adult setting. This monograph highlights those difficulties, reviewing disease-specific instances of the problems with transition from pediatric to adult neurologic care. The use of an arbitrary chronologic age cutoff for transition from pediatric to adult expertise in specific disease state may be a disservice in provision of care, and the disease-specific expertise of providers ...
Source: Neurologic Clinics - November 7, 2020 Category: Neurology Authors: Eugene R. Schnitzler, Michael J. Schneck Source Type: research
Therapy in Neurology
A decade ago, I had the privilege of serving as guest editor for an issue of the Neurologic Clinics dedicated to Advances in Neurologic Therapy. Who would have anticipated the proliferation of the newer, ongoing, and more selective therapeutic interventions that the current neurology practitioner has at his or her disposition? I humbly accepted serving once again as a guest editor with the specific intent of highlighting some of these state-of-the-art contemporary therapeutic advances, accepting the realization that therapeutic suggestions, although up-to-date as of this writing, mostly likely were going to be superseded b...
Source: Neurologic Clinics - November 7, 2020 Category: Neurology Authors: Jos é Biller Tags: Preface Source Type: research
Neurotoxicology
This article provides a basic approach to clinical assessment and causal inference. It addresses the knowledge gap for clinical practice and provides a thematic structure to use interdisciplinary resources. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 9, 2020 Category: Neurology Authors: Mam Ibraheem, Dong Y. Han, Michael R. Dobbs Source Type: research
