Clinical and radiological consequences of delayed therapy escalation in patients with relapsing-remitting multiple sclerosis
CONCLUSIONS: In everyday practice, the long-term outcomes in patients with RRMS and disease activity, despite DMT being used, are more favourable after early implementation of high-efficacy drugs. Delaying therapy escalation results in the accumulation of permanent disability in patients with RRMS.PMID:38112646 | DOI:10.5603/pjnns.97040 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Ma łgorzata Popiel Halina Bartosik-Psujek Source Type: research
Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research
Reperfusion therapy of ischaemic strokes in oral anticoagulated patients: an expanding field in clinical practice
Neurol Neurochir Pol. 2023 Dec 19. doi: 10.5603/pjnns.98603. Online ahead of print.NO ABSTRACTPMID:38112648 | DOI:10.5603/pjnns.98603 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Bartosz Karaszewski Source Type: research
Updates on pharmacological treatment for Alzheimer's disease: response to Letter to the Editors
Neurol Neurochir Pol. 2023 Dec 19. doi: 10.5603/pjnns.98249. Online ahead of print.NO ABSTRACTPMID:38112667 | DOI:10.5603/pjnns.98249 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Philip W Tipton Source Type: research
Cerebral amyloid angiopathy associated with Alzheimer's Disease: two pathologies from a single peptide?
Neurol Neurochir Pol. 2023 Dec 19. doi: 10.5603/pjnns.97901. Online ahead of print.NO ABSTRACTPMID:38112668 | DOI:10.5603/pjnns.97901 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Gabriele Gaggero Davide Taietti Veronica Parrella Pietro Fiaschi Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
Normal pressure hydrocephalus, or Hakim syndrome: review and update
Neurol Neurochir Pol. 2023 Dec 6. doi: 10.5603/pjnns.97343. Online ahead of print.ABSTRACTThis review makes the case that idiopathic normal pressure hydrocephalus (iNPH) is an outdated term because new information indicates that the syndrome is less idiopathic and that the cerebrospinal fluid (CSF) pressure of normal individuals is affected by several factors such as body mass index, age, and sex. Our review updates the epidemiology of iNPH and provides a clinical approach to the management of these patients. All the clinical features of iNPH are common in older individuals, and each has many causes, so the diagnosis is di...
Source: Neurologia i Neurochirurgia Polska - December 6, 2023 Category: Neurology Authors: Philip W Tipton Benjamin D Elder Petrice M Cogswell Neill Graff-Radford Source Type: research
