Comparative clinical study of medically controlled nonsevere chronic primary angle-closure glaucoma with coexisting cataract surgically managed by phacoemulsification as against combined phacotrabeculectomy
CONCLUSION: Phacoemulsification is equally effective in terms of intraocular pressure control and visual outcome as phacotrabeculectomy with better safety and less post-operative complication. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - January 4, 2019 Category: Opthalmology Authors: Vidya Chelerkar Puja Parekh V K S Kalyani Madan Deshpande Rajiv Khandekar Source Type: research

Iris melanoma in a child simulating juvenile xanthogranuloma
Jerry A Shields, Carol L Shields, Sara E Lally, Tatyana Milman, Ralph C EagleMiddle East African Journal of Ophthalmology 2018 25(2):115-117 An 8-year-old girl was referred for an amelanotic iris tumor believed to have enlarged slightly over 3 months, suspicious for juvenile xanthogranuloma (JXG). The affected right eye had a lightly pigmented, vascular iris mass measuring 6 mm in basal dimension and 2 mm in thickness. There were no feeder vessels, seeding, inflammatory cells, or cutaneous abnormalities. Diagnostic fine needle aspiration biopsy (FNAB) was performed, revealing spindle B melanoma cells that were immunoreact...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Jerry A Shields Carol L Shields Sara E Lally Tatyana Milman Ralph C Eagle Source Type: research

Botryoid rhabdomyosarcoma of the conjunctiva in a young boy
Justin D Pennington, R Joel Welch, Sara E Lally, Jerry A Shields, Ralph C Eagle, Carol L ShieldsMiddle East African Journal of Ophthalmology 2018 25(2):111-114 Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Molecular analysis revealed the absence of the PAX3/FOXO...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Justin D Pennington R Joel Welch Sara E Lally Jerry A Shields Ralph C Eagle Carol L Shields Source Type: research

Hand-held optical coherence tomography monitoring of submillimeter retinoblastoma treated with indocyanine green-enhanced transpupillary therapy
We report precise HH-OCT findings in a case of sub-millimeter retinoblastoma treated with foveal-sparing indocyanine green-enhanced transpupillary thermotherapy (ICG-TTT). A 2-month-old Caucasian female with bilateral Group B retinoblastoma showed two recurrent macular tumors in the right eye, demonstrating 88 μm and 37 μm of growth to 344 μm and 413 μm in thickness, respectively, on HH-OCT. Each was treated with additional intravenous chemotherapy and foveal-sparing ICG-TTT. Tumor regression to 154 μm and 224 μm was documented on HH-OCT and maintained...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Meredith A Spencer R Joel Welch Carol L Shields Source Type: research

Outcome analysis of visual acuity and side effect after ruthenium-106 plaque brachytherapy for medium-sized choroidal melanoma
CONCLUSIONS: The majority of patients maintained good visual acuity, with no enucleations and minimal side effects. In this cohort, the Ru-106 plaque brachytherapy proved to be an efficacious and safe treatment option for patients with medium-sized choroidal melanomas with a maximal tumor height of 5 mm. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Tahra AlMahmoud Sean Quinlan-Davidson Gregory R Pond Jean Desch & #234;nes Source Type: research

Characteristics and factors related to eyelid basal cell carcinoma in Saudi Arabia
CONCLUSION: BCC is a rare condition in Saudi Arabia. The clinical features and histopathology of BCC in Saudi Arabia are similar to the patterns observed in other regions of the world. Early detection and timely management mitigates the extensive destructive ocular/orbital damage due to BCC and results in better patient outcomes. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Manar Al Wohaib Reem Al Ahmadi Dalal Al Essa Azza Maktabbi Rajiv Khandekar Eman Al Sharif Hind Al Katan Silvana Artioli Schellini Osama Al Shaikh Source Type: research

Staging uveal melanoma with whole-body positron-emission tomography/computed tomography and abdominal ultrasound: Low incidence of metastatic disease, high incidence of second primary cancers
CONCLUSIONS: Whole-body PET/CT and abdominal ultrasound complement each other in the staging of uveal melanoma. Benign hepatic abnormalities found using ultrasound is common. Of importance, a second asymptomatic primary malignancy associated with uveal melanoma was detected almost one in 10 patients. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Victoria M L Cohen Efthymia Pavlidou Joanna Costa Amit K Arora Teressa Szyszko Mandeep S Sagoo Peter Szlosarek Source Type: research

Uveal metastasis: Clinical features and survival outcome of 2214 tumors in 1111 patients based on primary tumor origin
CONCLUSION: In a tertiary referral service, uveal metastasis originates from cancer in the breast, lung, kidney, GI tract, cutaneous melanoma, or others. Overall prognosis is poor with 5-year survival at 23% and worst survival with pancreatic metastasis whereas best survival with lung carcinoid metastasis. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Carol L Shields R Joel Welch Kunal Malik Luis A Acaba-Berrocal Evan B Selzer Jennifer H Newman Eileen L Mayro Alexandru B Constantinescu Meredith A Spencer Mark P McGarrey Austen N Knapp Alexander E Graf Alex J Altman Sean P Considine Jerry A Shields Source Type: research

Idiopathic orbital inflammation: Review of literature and new advances
Yağmur Seda Yeşiltaş, Ahmet Kaan GündüzMiddle East African Journal of Ophthalmology 2018 25(2):71-80 Idiopathic orbital inflammation (IOI) is a benign inflammatory condition usually confined to the orbit but extraorbital extension can also occur. IOI has been classified into categories including anterior, diffuse, posterior or apical, myositis, and dacryoadenitis. Other rare types of IOI include periscleritis, perineuritis, and focal mass. Diagnosis is based on careful history, clinical findings, computed tomography, and magnetic resonance imaging findings. An or...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Ya & #287;mur Seda Ye & #351;ilta & #351; Ahmet Kaan G & #252;nd & #252;z Source Type: research

Choroidal melanoma resection
Hany S Hamza, Abdelrahman M ElhusseinyMiddle East African Journal of Ophthalmology 2018 25(2):65-70 Uveal melanoma is the most common intraocular malignant tumor, with the choroid being the most common site. Management of choroidal melanoma has evolved greatly over the past years. In the past, the conventional method of treatment was enucleation of the affected eye with a debate regarding the effect of enucleation to promote or prevent metastasis. However, nowadays, there are many therapeutic options available including plaque radiotherapy, proton beam radiotherapy, argon laser photocoagulation, transpupillary thermothera...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Hany S Hamza Abdelrahman M Elhusseiny Source Type: research

Orbital metastases: When to suspect ? When to biopsy ?
Richard Cutler AllenMiddle East African Journal of Ophthalmology 2018 25(2):60-64 Incidental orbital masses that are asymptomatic and appear benign are often observed without surgical intervention unless there is a clinical or radiographic change in the mass. There is a burgeoning population of cancer patients with incidental masses that have been detected while under surveillance for metastasis. This population of patients is growing due to a number of reasons, including more extensive imaging, an aging population, and more effective cancer treatments. Closer scrutiny should be applied to these patients, due to the possi...
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Richard Cutler Allen Source Type: research

Ocular oncology: Saving sight, saving lives
Ahmet Kaan GündüzMiddle East African Journal of Ophthalmology 2018 25(2):59-59 (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - July 18, 2018 Category: Opthalmology Authors: Ahmet Kaan G & #252;nd & #252;z Source Type: research

Implantation of customized, preshaped implant for orbital fractures with the aid of three-dimensional printing
Sirous Nekooei, Mahsa Sardabi, Mohammad Etezad Razavi, Amirhossein Nekooei, Mohammad Yaser KiarudiMiddle East African Journal of Ophthalmology 2018 25(1):56-58 Orbital floor fractures alone or in conjunction with other facial skeletal fractures are the most commonly encountered midfacial fractures. The technological advances in 3-dimensional (3D) printing allow the physical prototyping of 3D models, so creates an accurate representation of the patient's specific anatomy. A 56-year-old Caucasian man with severe hypoglobus and enophthalmos with an extensive blowout fracture was scheduled for reconstruction. First...
Source: Middle East African Journal of Ophthalmology - May 18, 2018 Category: Opthalmology Authors: Sirous Nekooei Mahsa Sardabi Mohammad Etezad Razavi Amirhossein Nekooei Mohammad Yaser Kiarudi Source Type: research

Bilateral deep sclerectomy with microperforations as a successful secondary procedure in aniridia-associated glaucoma
Abdulrahman AlDarrab, Rizwan MalikMiddle East African Journal of Ophthalmology 2018 25(1):52-55 Aniridia-associated glaucoma is often refractory to medical treatment. Glaucoma drainage device surgery is often considered after failed angle surgery. However, the potential complications of tube surgery in young children are not negligible. The failure rate of conventional trabeculectomy may be high and can require close and multiple postoperative follow-up visits. Here, we describe a child with aniridia who achieved good short-term results with deep sclerectomy. A 14-month-old girl was referred to our unit following bilatera...
Source: Middle East African Journal of Ophthalmology - May 18, 2018 Category: Opthalmology Authors: Abdulrahman AlDarrab Rizwan Malik Source Type: research

Palmoplantar keratoderma with keratoconus
We report, for the first time, a case of bilateral keratoconus in a patient with PPK. (Source: Middle East African Journal of Ophthalmology)
Source: Middle East African Journal of Ophthalmology - May 18, 2018 Category: Opthalmology Authors: Ved Prakash Gupta Isha Chaudhari Source Type: research