S1P-S1PR3-RAS promotes the progression of S1PR3hi TAL1+ T-cell acute lymphoblastic leukemia that can be effectively inhibited by an S1PR3 antagonist
Leukemia, Published online: 17 August 2023; doi:10.1038/s41375-023-02000-0S1P-S1PR3-RAS promotes the progression of S1PR3hi TAL1+ T-cell acute lymphoblastic leukemia that can be effectively inhibited by an S1PR3 antagonist (Source: Leukemia)
Source: Leukemia - August 17, 2023 Category: Hematology Authors: Dan Zhu Tingting Jiang Deyu Ma Hongyang Zhang Jia Zhang Wenqiong Lv Maoyuan Gong Haobiao Wang Ziyang Liu Hongyu Su Lamei Zeng Shan Liu Shi Tang Bijie Yang Filippus I. Tshavuka Guo Fu Zidai Liu Danyi Peng Haiyan Liu Zijun Yan Ziyang Cao Hui Zhao Tong-Chuan Source Type: research

Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis
Leukemia, Published online: 17 August 2023; doi:10.1038/s41375-023-02007-7Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis (Source: Leukemia)
Source: Leukemia - August 17, 2023 Category: Hematology Authors: Natalia J. Gurule Kenneth C. Malcolm Chelsea Harris Jennifer R. Knapp Brian P. O ’Connor Jazalle McClendon William J. Janssen Frank Fang Yao Lee Caitlin Price Jackson Osaghae-Nosa Emily A. Wheeler Christine M. McMahon Eric M. Pietras Daniel A. Pollyea S Source Type: research

Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients
Leukemia, Published online: 17 August 2023; doi:10.1038/s41375-023-01999-6Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients (Source: Leukemia)
Source: Leukemia - August 17, 2023 Category: Hematology Authors: Ekaterina Jahn Maral Saadati Pierre Fenaux Marco Gobbi Gail J. Roboz Lars Bullinger Pavlo Lutsik Anna Riedel Christoph Plass Nikolaus Jahn Claudia Walter Karlheinz Holzmann Yong Hao Sue Naim Nicholas Schreck Julia Krzykalla Axel Benner Harold N. Keer Moha Source Type: research

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia
Leukemia, Published online: 16 August 2023; doi:10.1038/s41375-023-02005-9Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - August 16, 2023 Category: Hematology Authors: Theresa Eifert Chen-Jen Hsu Alicia L. Becker Sarah Graessle Arik Horne Franziska Bemmann Qirui Zhang Michael Heuser Valeri Vasioukhin Sebastian Scholl Andreas Hochhaus Florian Siegerist Nicole Endlich Lars Bullinger Steven W. Lane Simon Haas Tina M. Schno Source Type: research

Perspectives on acute myeloid leukemia diagnosis: a comparative analysis of the latest World Health Organization and the International Consensus Classifications
Leukemia, Published online: 14 August 2023; doi:10.1038/s41375-023-01996-9Perspectives on acute myeloid leukemia diagnosis: a comparative analysis of the latest World Health Organization and the International Consensus Classifications (Source: Leukemia)
Source: Leukemia - August 14, 2023 Category: Hematology Authors: Jin Jung Daehun Kwag Yonggoo Kim Jong-Mi Lee Ari Ahn Hoon Seok Kim Byunggyu Bae Silvia Park Hee-Je Kim Byung-Sik Cho Myungshin Kim Source Type: research

CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma
Leukemia, Published online: 12 August 2023; doi:10.1038/s41375-023-01997-8CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma (Source: Leukemia)
Source: Leukemia - August 12, 2023 Category: Hematology Authors: Neetha Parameswaran Liping Luo Lingjun Zhang Joel Chen Frank P. DiFilippo Charlie Androjna David A. Fox Sarah L. Ondrejka Eric D. Hsi Deepa Jagadeesh Daniel J. Lindner Feng Lin Source Type: research

Risk assessment according to IPSS-M is superior to AML ELN risk classification in MDS/AML overlap patients defined by ICC
Leukemia, Published online: 12 August 2023; doi:10.1038/s41375-023-02004-wRisk assessment according to IPSS-M is superior to AML ELN risk classification in MDS/AML overlap patients defined by ICC (Source: Leukemia)
Source: Leukemia - August 12, 2023 Category: Hematology Authors: Sandra Huber Constance Baer Stephan Hutter Frank Dicker Irene Fuhrmann Manja Meggendorfer Christian Pohlkamp Wolfgang Kern Torsten Haferlach Claudia Haferlach Gregor Hoermann Source Type: research

Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation
Leukemia, Published online: 11 August 2023; doi:10.1038/s41375-023-01998-7Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation (Source: Leukemia)
Source: Leukemia - August 11, 2023 Category: Hematology Authors: Jakob Nordberg N ørgaard Niels Abildgaard Anna Lys én Galina Tsykunova Annette Juul Vangsted Cristina Jo ão Nora Remen Lene Kongsgaard Nielsen Liv Osnes Caroline Stokke James P. Connelly Mona-Elisabeth R. Revheim Fredrik Schjesvold Source Type: research

Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms
Leukemia, Published online: 10 August 2023; doi:10.1038/s41375-023-01995-wNovel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms (Source: Leukemia)
Source: Leukemia - August 10, 2023 Category: Hematology Authors: Sabrina Kalmbach Michael Grau Myroslav Zapukhlyak Ellen Leich Vindi Jurinovic Eva Hoster Annette M. Staiger Katrin S. Kurz Oliver Weigert Erik Gaitzsch Verena Passerini Marianne Engelhard Klaus Herfarth Klaus Beiske Francesca Micci Peter M öller Heinz-Wo Source Type: research

FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML
Leukemia, Published online: 09 August 2023; doi:10.1038/s41375-023-01994-xFLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML (Source: Leukemia)
Source: Leukemia - August 9, 2023 Category: Hematology Authors: Jad Othman Nicola Potter Katya Mokretar David Taussig Anjum Khan Pramila Krishnamurthy Anne-Louise Latif Paul Cahalin James Aries Mariam Amer Edward Belsham Eibhlin Conneally Charles Craddock Dominic Culligan Mike Dennis Caroline Duncan Sylvie D. Freeman Source Type: research

Rituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia
Leukemia, Published online: 05 August 2023; doi:10.1038/s41375-023-01992-zRituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia (Source: Leukemia)
Source: Leukemia - August 5, 2023 Category: Hematology Authors: Keito Hoshitsuki Yinmei Zhou April M. Miller John K. Choi Hope D. Swanson Nickhill H. Bhakta Sima Jeha Seth E. Karol Raul C. Ribeiro Jeffrey E. Rubnitz Charles G. Mullighan Cheng Cheng Jun J. Yang Mary V. Relling Ching-Hon Pui Hiroto Inaba Source Type: research

A novel germline PAX5 single exon deletion in a pediatric patient with precursor B-cell leukemia
Leukemia, Published online: 05 August 2023; doi:10.1038/s41375-023-01991-0A novel germline PAX5 single exon deletion in a pediatric patient with precursor B-cell leukemia (Source: Leukemia)
Source: Leukemia - August 5, 2023 Category: Hematology Authors: N. van Engelen M. Roest F. van Dijk E. Sonneveld R. Bladergroen S. V. van Reijmersdal V. H. J. van der Velden P. G. Hoogeveen W. A. Kors E. Waanders M. C. J. Jongmans R. P. Kuiper Source Type: research

Skin lesions, arthritis, chondritis, and cytopenias
Leukemia, Published online: 04 August 2023; doi:10.1038/s41375-023-01988-9Skin lesions, arthritis, chondritis, and cytopenias (Source: Leukemia)
Source: Leukemia - August 4, 2023 Category: Hematology Authors: Edwin U. Su árez Elena Prieto Miguel Ángel González-Gay Carlos Soto Carlos Blas Luis Requena-Caballero Source Type: research

What role for somatic mutations in systemic inflammatory and autoimmune diseases associated with myelodysplastic neoplasms and chronic myelomonocytic leukemias?
Leukemia, Published online: 04 August 2023; doi:10.1038/s41375-023-01990-1What role for somatic mutations in systemic inflammatory and autoimmune diseases associated with myelodysplastic neoplasms and chronic myelomonocytic leukemias? (Source: Leukemia)
Source: Leukemia - August 4, 2023 Category: Hematology Authors: Lin-Pierre Zhao Pierre Fenaux Source Type: research

A C/ebpα isoform specific differentiation program in immortalized myelocytes
Leukemia, Published online: 02 August 2023; doi:10.1038/s41375-023-01989-8A C/ebpα isoform specific differentiation program in immortalized myelocytes (Source: Leukemia)
Source: Leukemia - August 2, 2023 Category: Hematology Authors: Maria-Paz Garcia-Cuellar Selin Akan Robert K. Slany Source Type: research