Phase III randomized trial of Thal+ZLD versus ZLD in patients with asymptomatic multiple myeloma – updated results after 18-year follow-up
Leukemia, Published online: 28 February 2024; doi:10.1038/s41375-024-02192-zPhase III randomized trial of Thal+ZLD versus ZLD in patients with asymptomatic multiple myeloma – updated results after 18-year follow-up (Source: Leukemia)
Source: Leukemia - February 28, 2024 Category: Hematology Authors: Nadine Abdallah Thomas E. Witzig Shaji K. Kumar Martha Q. Lacy Suzanne R. Hayman Angela Dispenzieri Vivek Roy Morie A. Gertz P. Leif Bergsagel S. Vincent Rajkumar Source Type: research

Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia
Leukemia, Published online: 28 February 2024; doi:10.1038/s41375-024-02190-1Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia (Source: Leukemia)
Source: Leukemia - February 28, 2024 Category: Hematology Authors: Guillermo Montalban-Bravo Juan Jose Rodriguez-Sevilla David Michael Swanson Rashmi Kanagal-Shamanna Danielle Hammond Kelly Chien Koji Sasaki Elias Jabbour Courtney DiNardo Koichi Takahashi Nicholas Short Ghayas C. Issa Naveen Pemmaraju Tapan Kadia Farhad Source Type: research

Correction: Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial
Leukemia, Published online: 28 February 2024; doi:10.1038/s41375-024-02184-zCorrection: Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial (Source: Leukemia)
Source: Leukemia - February 28, 2024 Category: Hematology Authors: Hjalmar Flygt Stina S öderlund Johan Richter Susanne Saussele Perttu Koskenvesa Leif Stenke Satu Mustjoki Andreja Dimitrijevic Jesper Stentoft Waleed Majeed Lydia Roy Dominik Wolf Arta Dreimane Bj ørn Tore Gjertsen Tobias Gedde-Dahl Erik Ahlstrand Berit Source Type: research

Germline variants in patients developing second malignant neoplasms after therapy for pediatric acute lymphoblastic leukemia—a case-control study
Leukemia, Published online: 27 February 2024; doi:10.1038/s41375-024-02173-2Germline variants in patients developing second malignant neoplasms after therapy for pediatric acute lymphoblastic leukemia—a case-control study (Source: Leukemia)
Source: Leukemia - February 27, 2024 Category: Hematology Authors: Stefanie V. Junk Alisa F örster Gunnar Schmidt Martin Zimmermann Birthe Fedders Bernd Haermeyer Anke K. Bergmann Anja M öricke Gunnar Cario Bernd Auber Martin Schrappe Christian P. Kratz Martin Stanulla Source Type: research

Long-term outcomes by bone marrow B-cell depletion from the R2W trial of bortezomib with cyclophosphamide and rituximab in Waldenstrőm macroglobulinaemia
Leukemia, Published online: 26 February 2024; doi:10.1038/s41375-024-02162-5Long-term outcomes by bone marrow B-cell depletion from the R2W trial of bortezomib with cyclophosphamide and rituximab in Waldenstrőm macroglobulinaemia (Source: Leukemia)
Source: Leukemia - February 26, 2024 Category: Hematology Authors: Ruth de Tute Nicholas Counsell Laura Clifton-Hadley Shirley D ’Sa Guy Pratt Gavin Campbell Lauren Campbell Ross Sadler William Townsend Bilyana Popova Paul Smith Oliver Schofield Roger Owen Rebecca Auer Source Type: research

Ferritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells
Leukemia, Published online: 24 February 2024; doi:10.1038/s41375-024-02169-yFerritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells (Source: Leukemia)
Source: Leukemia - February 24, 2024 Category: Hematology Authors: Weiwei Yi Jinhua Zhang Yingxin Huang Qiang Zhan Mi Zou Xiang Cheng Xuguang Zhang Zhinan Yin Si Tao Hui Cheng Fudi Wang Jun Guo Zhenyu Ju Zhiyang Chen Source Type: research

The evolution of preclinical models for myelodysplastic neoplasms
Leukemia, Published online: 23 February 2024; doi:10.1038/s41375-024-02181-2The evolution of preclinical models for myelodysplastic neoplasms (Source: Leukemia)
Source: Leukemia - February 23, 2024 Category: Hematology Authors: Alain Mina Steven Pavletic Peter D. Aplan Source Type: research

Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry
Leukemia, Published online: 23 February 2024; doi:10.1038/s41375-024-02183-0Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry (Source: Leukemia)
Source: Leukemia - February 23, 2024 Category: Hematology Authors: Ekaterina Chelysheva Jane Apperley Anna Turkina Mohamed A. Yassin Delphine Rea Franck E. Nicolini Daniela Barraco Khamida Kazakbaeva Sukhrob Saliev Adi Shacham Abulafia Salam Al-Kindi Jennifer Byrne Harry F. Robertson Marco Cerrano Roman Shmakov Evgenia P Source Type: research

Leukemogenesis occurs in a microenvironment enriched by extracellular microvesicles/exosomes: recent discoveries and questions to be answered
Leukemia, Published online: 22 February 2024; doi:10.1038/s41375-024-02188-9Leukemogenesis occurs in a microenvironment enriched by extracellular microvesicles/exosomes: recent discoveries and questions to be answered (Source: Leukemia)
Source: Leukemia - February 22, 2024 Category: Hematology Authors: Mariusz Z. Ratajczak Janina Ratajczak Source Type: research

Impact of socioeconomic disparities on outcomes in adults undergoing allogeneic hematopoietic cell transplantation for acute myeloid leukemia
Leukemia, Published online: 22 February 2024; doi:10.1038/s41375-024-02172-3Impact of socioeconomic disparities on outcomes in adults undergoing allogeneic hematopoietic cell transplantation for acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - February 22, 2024 Category: Hematology Authors: Daniel J. Olivieri Megan Othus Corentin Orvain Eduardo Rodr íguez-Arbolí Filippo Milano Brenda M. Sandmaier Irum Khan Chris Davis Ryan S. Basom Frederick R. Appelbaum Roland B. Walter Source Type: research

Phase 2 study using low dose cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis
Leukemia, Published online: 22 February 2024; doi:10.1038/s41375-024-02174-1Phase 2 study using low dose cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis (Source: Leukemia)
Source: Leukemia - February 22, 2024 Category: Hematology Authors: Long Chang Min Lang He Lin Hao Cai Ming-Hui Duan Dao-Bin Zhou Xin-Xin Cao Source Type: research

Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma
Leukemia, Published online: 20 February 2024; doi:10.1038/s41375-024-02171-4Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma (Source: Leukemia)
Source: Leukemia - February 20, 2024 Category: Hematology Authors: Zegeng Chen He Huang Huageng Huang Le Yu Huawei Weng Jian Xiao Liqun Zou Huilai Zhang Chaoyong Liang Hui Zhou Hongqiang Guo Zhao Wang Zhiming Li Tao Wu Hongyu Zhang Huijing Wu Zhigang Peng Linzhu Zhai Xinggui Chen Yang Liang Huangming Hong Tongyu Lin Source Type: research

Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis
Leukemia, Published online: 20 February 2024; doi:10.1038/s41375-024-02170-5Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis (Source: Leukemia)
Source: Leukemia - February 20, 2024 Category: Hematology Authors: H élène Duparc Delphine Muller Laure Gilles Agathe L. Ch édeville Mira El Khoury Rose Guignard Najet Debili Monika Wittner Alexandre Kauskot Florence Pasquier Il éana Antony-Debré Caroline Marty William Vainchenker Isabelle Plo Hana Raslova Source Type: research

Hypomethylating agents plus venetoclax compared with intensive induction chemotherapy regimens in molecularly defined secondary AML
Leukemia, Published online: 20 February 2024; doi:10.1038/s41375-024-02175-0Hypomethylating agents plus venetoclax compared with intensive induction chemotherapy regimens in molecularly defined secondary AML (Source: Leukemia)
Source: Leukemia - February 20, 2024 Category: Hematology Authors: Shai Shimony Jan Philipp Bewersdorf Rory M. Shallis Yiwen Liu Eva J. Schaefer Amer M. Zeidan Aaron D. Goldberg Eytan M. Stein Guido Marcucci R. Coleman Lindsley Evan C. Chen Jorge Ramos Perez Anthony Stein Daniel J. DeAngelo Donna S. Neuberg Richard M. St Source Type: research

Germline CHEK2 mutations in patients with myeloid neoplasms
Leukemia, Published online: 20 February 2024; doi:10.1038/s41375-024-02179-wGermline CHEK2 mutations in patients with myeloid neoplasms (Source: Leukemia)
Source: Leukemia - February 20, 2024 Category: Hematology Authors: Lucie Freiman Lise Larcher Giulia Tueur Nadia Vasquez M élanie Da Costa Matthieu Duchmann Emmanuel Raffoux Lionel Ad ès Pierre Fenaux Jean Soulier Nicolas Duployez Emmanuelle Clappier Marie S ébert Source Type: research