FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia
Leukemia, Published online: 05 January 2024; doi:10.1038/s41375-023-02131-4FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - January 5, 2024 Category: Hematology Authors: Pamela J. Sung Murugan Selvam Simone S. Riedel Hongbo M. Xie Katie Bryant Bryan Manning Gerald B. Wertheim Katarzyna Kulej Lucie Pham Robert L. Bowman Jennifer Peresie Michael J. Nemeth Ross L. Levine Benjamin A. Garcia Sara E. Meyer Simone Sidoli Kathrin Source Type: research

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis
Leukemia, Published online: 04 January 2024; doi:10.1038/s41375-023-02118-1Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis (Source: Leukemia)
Source: Leukemia - January 4, 2024 Category: Hematology Authors: Sandeep Potluri Sophie G. Kellaway Daniel J. L. Coleman Peter Keane Maria Rosaria Imperato Salam A. Assi Peter N. Cockerill Constanze Bonifer Source Type: research

How to interpret the EURO-SKI study and its treatment-free remission outcome. Reply to R.P. Gale and J. Chen
Leukemia, Published online: 03 January 2024; doi:10.1038/s41375-023-02124-3How to interpret the EURO-SKI study and its treatment-free remission outcome. Reply to R.P. Gale and J. Chen (Source: Leukemia)
Source: Leukemia - January 3, 2024 Category: Hematology Authors: Markus Pfirrmann Susanne Saussele Fran çois-Xavier Mahon Johan Richter Source Type: research

Genetic and transcriptomic analyses of diffuse large B-cell lymphoma patients with poor outcomes within two years of diagnosis
Leukemia, Published online: 29 December 2023; doi:10.1038/s41375-023-02120-7Genetic and transcriptomic analyses of diffuse large B-cell lymphoma patients with poor outcomes within two years of diagnosis (Source: Leukemia)
Source: Leukemia - December 29, 2023 Category: Hematology Authors: Weicheng Ren Hui Wan Sulaf Abd Own Mattias Berglund Xianhuo Wang Mingyu Yang Xiaobo Li Dongbing Liu Xiaofei Ye Kristina Sonnevi Gunilla Enblad Rose-Marie Amini Birgitta Sander Kui Wu Huilai Zhang Bj örn Engelbrekt Wahlin Karin E. Smedby Qiang Pan-Hammars Source Type: research

Pre-diagnosis dietary patterns and risk of multiple myeloma in the NIH-AARP diet and health study
Leukemia, Published online: 29 December 2023; doi:10.1038/s41375-023-02132-3Pre-diagnosis dietary patterns and risk of multiple myeloma in the NIH-AARP diet and health study (Source: Leukemia)
Source: Leukemia - December 29, 2023 Category: Hematology Authors: Francesca Castro Richa Parikh Jelyn C. Eustaquio Andriy Derkach Janine M. Joseph Alexander M. Lesokhin Saad Z. Usmani Urvi A. Shah Source Type: research

In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile
Leukemia, Published online: 28 December 2023; doi:10.1038/s41375-023-02122-5In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile (Source: Leukemia)
Source: Leukemia - December 28, 2023 Category: Hematology Authors: Ho-Jae Han Jaeyoon John Kim Danielle Pyne Anthea Travas Amirthagowri Ambalavanan Shinya Kimura Michael W. Deininger Jong-Won Kim Dennis Dong Hwan Kim Source Type: research

Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL
Leukemia, Published online: 28 December 2023; doi:10.1038/s41375-023-02123-4Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL (Source: Leukemia)
Source: Leukemia - December 28, 2023 Category: Hematology Authors: Geoffrey Parriott Emma Hegermiller Rosemary E. Morman Cameron Frank Caner Saygin Wendy Stock Elizabeth T. Bartom Barbara L. Kee Source Type: research

Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification
Leukemia, Published online: 27 December 2023; doi:10.1038/s41375-023-02114-5Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification (Source: Leukemia)
Source: Leukemia - December 27, 2023 Category: Hematology Authors: H élène Pasquer Rafael Daltro de Oliveira Loic Vasseur Juliette Soret-Dulphy Nabih Maslah Lin-Pierre Zhao Cl émence Marcault Marine Cazaux Nicolas Gauthier Emmanuelle Verger Nathalie Parquet William Vainchenker Emmanuel Raffoux Val érie Ugo Damien Luq Source Type: research

Response to Pfirrmann et al.’s comment on How should we interpret conclusions of TKI-stopping studies
Leukemia, Published online: 27 December 2023; doi:10.1038/s41375-023-02128-zResponse to Pfirrmann et al.’s comment on How should we interpret conclusions of TKI-stopping studies (Source: Leukemia)
Source: Leukemia - December 27, 2023 Category: Hematology Authors: Junren Chen Robert Peter Gale Source Type: research

Mitochondrial regulation of GPX4 inhibition–mediated ferroptosis in acute myeloid leukemia
Leukemia, Published online: 26 December 2023; doi:10.1038/s41375-023-02117-2Mitochondrial regulation of GPX4 inhibition–mediated ferroptosis in acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - December 26, 2023 Category: Hematology Authors: Hiroki Akiyama Ran Zhao Lauren B. Ostermann Ziyi Li Matthew Tcheng Samar J. Yazdani Arman Moayed Malcolm L. Pryor II Sandeep Slngh Natalia Baran Edward Ayoub Yuki Nishida Po Yee Mak Vivian R. Ruvolo Bing Z. Carter Aaron D. Schimmer Michael Andreeff Jo Ish Source Type: research

Interleukin-15 and -21-activated, donor-derived NK cell infusion after haploidentical HCT in high-risk AML and MDS—a cohort analysis
Leukemia, Published online: 22 December 2023; doi:10.1038/s41375-023-02121-6Interleukin-15 and -21-activated, donor-derived NK cell infusion after haploidentical HCT in high-risk AML and MDS—a cohort analysis (Source: Leukemia)
Source: Leukemia - December 22, 2023 Category: Hematology Authors: Kyoo-Hyung Lee Sewon Lee Young Hoon Park Yeung-Chul Mun Eun-Ji Choi Yunsuk Choi Han-Seung Park Jung-Hee Lee Je-Hwan Lee Soo-Yeon Park Suk Ran Yoon Inpyo Choi Source Type: research

Real life evaluation of AlphaMissense predictions in hematological malignancies
Leukemia, Published online: 22 December 2023; doi:10.1038/s41375-023-02116-3Real life evaluation of AlphaMissense predictions in hematological malignancies (Source: Leukemia)
Source: Leukemia - December 22, 2023 Category: Hematology Authors: Kaddour Chabane Carole Charlot Dan Gugenheim Thomas Simonet David Armisen Pierre-Julien Viailly Guillaume Codet de Boisse Sarah Huet Sandrine Hayette Vincent Alcazer Pierre Sujobert Source Type: research

Allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia not in remission
Leukemia, Published online: 21 December 2023; doi:10.1038/s41375-023-02119-0Allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia not in remission (Source: Leukemia)
Source: Leukemia - December 21, 2023 Category: Hematology Authors: Masamitsu Yanada Satoshi Yamasaki Tadakazu Kondo Takahito Kawata Kaito Harada Naoyuki Uchida Noriko Doki Satoshi Yoshihara Yuta Katayama Tetsuya Eto Masatsugu Tanaka Satoru Takada Toshiro Kawakita Tetsuya Nishida Shuichi Ota Kentaro Serizawa Makoto Onizuk Source Type: research

The SNP rs460089 in the gene promoter of the drug transporter OCTN1 has prognostic value for treatment-free remission in chronic myeloid leukemia patients treated with imatinib
Leukemia, Published online: 21 December 2023; doi:10.1038/s41375-023-02109-2The SNP rs460089 in the gene promoter of the drug transporter OCTN1 has prognostic value for treatment-free remission in chronic myeloid leukemia patients treated with imatinib (Source: Leukemia)
Source: Leukemia - December 21, 2023 Category: Hematology Authors: Katerina Machova Polakova Ali Albeer Vaclava Polivkova Monika Krutska Katerina Vlcanova Nikola Curik Alice Fabarius Hana Klamova Birgit Spiess Cornelius F. Waller Tim H. Br ümmendorf Jolanta Dengler Volker Kunzmann Andreas Burchert Petra Belohlavkova Sat Source Type: research

Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7
Leukemia, Published online: 20 December 2023; doi:10.1038/s41375-023-02113-6Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7 (Source: Leukemia)
Source: Leukemia - December 20, 2023 Category: Hematology Authors: Michael C. Kann Emily M. Schneider Antonio J. Almazan Isabel C. Lane Amanda A. Bouffard Valentina M. Supper Hana N. Takei Alexander Tepper Mark B. Leick Rebecca C. Larson Benjamin L. Ebert Marcela V. Maus Max Jan Source Type: research