Dose modification dynamics of ponatinib in patients with chronic-phase chronic myeloid leukemia (CP-CML) from the PACE and OPTIC trials
Leukemia, Published online: 29 January 2024; doi:10.1038/s41375-024-02159-0Dose modification dynamics of ponatinib in patients with chronic-phase chronic myeloid leukemia (CP-CML) from the PACE and OPTIC trials (Source: Leukemia)
Source: Leukemia - January 29, 2024 Category: Hematology Authors: Elias Jabbour Jane Apperley Jorge Cortes Delphine Rea Michael Deininger Elisabetta Abruzzese Charles Chuah Daniel J. DeAngelo Andreas Hochhaus Jeffrey H. Lipton Michael Mauro Franck Nicolini Javier Pinilla-Ibarz Gianantonio Rosti Philippe Rousselot Neil P Source Type: research

Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia
Leukemia, Published online: 29 January 2024; doi:10.1038/s41375-024-02153-6Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia (Source: Leukemia)
Source: Leukemia - January 29, 2024 Category: Hematology Authors: Merete Dam Maddalena Centanni Lena E. Friberg Daniel Centanni Mats O. Karlsson Line Stensig Lynggaard Inga Maria Johannsdottir Hilde Skuterud Wik Johan Malmros Goda Elizabeta Vaitkeviciene Laimonas Griskevicius Helene Hallb öök Ólafur Gísli Jónsson U Source Type: research

Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial
Leukemia, Published online: 26 January 2024; doi:10.1038/s41375-024-02145-6Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial (Source: Leukemia)
Source: Leukemia - January 26, 2024 Category: Hematology Authors: Hjalmar Flygt Stina S öderlund Johan Richter Susanne Saussele Perttu Koskenvesa Leif Stenke Satu Mustjoki Andreja Dimitrijevic Jesper Stentoft Waleed Majeed Lydia Roy Dominik Wolf Arta Dreimane Bj ørn Tore Gjertsen Tobias Gedde-Dahl Erik Ahlstrand Berit Source Type: research

Correction to: TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia
Leukemia, Published online: 25 January 2024; doi:10.1038/s41375-023-02125-2Correction to: TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia (Source: Leukemia)
Source: Leukemia - January 25, 2024 Category: Hematology Authors: Shi Hao Tan Tze King Tan Rui Yokomori Minghui Liao Xiao Zi Huang Allen Eng Juh Yeoh Takaomi Sanda Source Type: research

Impact of hemodilution on flow cytometry based measurable residual disease assessment in acute myeloid leukemia
Leukemia, Published online: 25 January 2024; doi:10.1038/s41375-024-02158-1Impact of hemodilution on flow cytometry based measurable residual disease assessment in acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - January 25, 2024 Category: Hematology Authors: Jesse M. Tettero Maaike E. Heidinga Tim R. Mocking Glenn Fransen Ang èle Kelder Willemijn J. Scholten Alexander N. Snel Lok Lam Ngai Costa Bachas Arjan A. van de Loosdrecht Gert J. Ossenkoppele David C. de Leeuw Jacqueline Cloos Jeroen J. W. M. Janssen Source Type: research

The new WHO 2022 and ICC proposals for the classification of myelodysplastic neoplasms. Validation based on the Düsseldorf MDS Registry and proposals for a merged classification
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02157-2The new WHO 2022 and ICC proposals for the classification of myelodysplastic neoplasms. Validation based on the Düsseldorf MDS Registry and proposals for a merged classification (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: K. Nachtkamp C. Strupp M. Vukelja A. Kasprzak D. Haase C. Ganster B. Hildebrandt B. Betz A. Giagounidis C. Aul S. Blum W. K. Hofmann M. Pfeilst öcker P. Valent M. L übbert M. Seidl M. Rudelius R. Stauder O. Krieger K. S. G ötze J. Bobak A. K ündgen F. Source Type: research

Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02143-8Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Jacob S. Appelbaum Andrew H. Wei Sumithra J. Mandrekar Ing S. Tiong Chong Chyn Chua Tse-Chieh Teh Chun Yew Fong Stephen B. Ting Daniela Weber Axel Benner Hannah Hill Maral Saadati Jun Yin Richard M. Stone Guillermo Garcia-Manero Harry P. Erba Geoffrey L. Source Type: research

Concerns regarding myelofibrosis-type megakaryocyte dysplasia
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02160-7Concerns regarding myelofibrosis-type megakaryocyte dysplasia (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Yanan Cai Yuebo Wang Jing Yang Zunmin Zhu Source Type: research

Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02147-4Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Harpreet K. Mandhair Ramin Radpour Mira Westerhuis Yara Banz Magali Humbert Miroslav Arambasic J örn Dengjel Andrew Davies Mario P. Tschan Urban Novak Source Type: research

Peri-transplant flow-MRD assessment of cells with leukemic stem cells (LSC) associated phenotype in AML patients undergoing allogeneic stem cell transplantation in CR
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02148-3Peri-transplant flow-MRD assessment of cells with leukemic stem cells (LSC) associated phenotype in AML patients undergoing allogeneic stem cell transplantation in CR (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Evgeny Klyuchnikov Anita Badbaran Radwan Massoud Petra Freiberger Christine Wolschke Francis Ayuk Boris Fehse Ulrike Bacher Nicolaus Kr öger Source Type: research

Inherent genome instability underlies trisomy 21-associated myeloid malignancies
Leukemia, Published online: 20 January 2024; doi:10.1038/s41375-024-02151-8Inherent genome instability underlies trisomy 21-associated myeloid malignancies (Source: Leukemia)
Source: Leukemia - January 20, 2024 Category: Hematology Authors: Chun-Chin Chen Rebecca E. Silberman Duanduan Ma Jennifer A. Perry Delan Khalid Yana Pikman Angelika Amon Michael T. Hemann R. Grant Rowe Source Type: research

Real-world analysis of teclistamab in 123 RRMM patients from Germany
Leukemia, Published online: 20 January 2024; doi:10.1038/s41375-024-02154-5Real-world analysis of teclistamab in 123 RRMM patients from Germany (Source: Leukemia)
Source: Leukemia - January 20, 2024 Category: Hematology Authors: C. Riedhammer F. Bassermann B. Besemer M. Bewarder F. Brunner A. Carpinteiro H. Einsele J. Faltin J. Frenking D. Gezer S. Goldman-Mazur M. H änel M. Hoegner K. M. Kortuem J. Kr önke M. Kull T. Leitner C. Mann R. Mecklenbrauck M. Merz A. Morgner A. Nogai Source Type: research

Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis
Leukemia, Published online: 19 January 2024; doi:10.1038/s41375-024-02149-2Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis (Source: Leukemia)
Source: Leukemia - January 19, 2024 Category: Hematology Authors: Mohamed Eldeeb Anna Konturek-Ciesla Qinyu Zhang Shabnam Kharazi Johanna Tingvall-Gustafsson Jonas Ungerb äck Mikael Sigvardsson David Bryder Source Type: research

Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation
Leukemia, Published online: 18 January 2024; doi:10.1038/s41375-024-02152-7Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation (Source: Leukemia)
Source: Leukemia - January 18, 2024 Category: Hematology Authors: Yasuhiro Kambara Daichi Sadato Takashi Toya Akira Honda Seiko Kato Chizuko Hirama Kyoko Haraguchi Hiroaki Shimizu Yuho Najima Takeshi Kobayashi Yoshiki Okuyama Hironori Harada Satoshi Takahashi Mineo Kurokawa Yuka Harada Noriko Doki Source Type: research

Lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH): a scoping review unveils clinical and diagnostic patterns of a lymphoma subgroup with poor prognosis
Leukemia, Published online: 18 January 2024; doi:10.1038/s41375-024-02135-8Lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH): a scoping review unveils clinical and diagnostic patterns of a lymphoma subgroup with poor prognosis (Source: Leukemia)
Source: Leukemia - January 18, 2024 Category: Hematology Authors: Johanna Knauft Thomas Schenk Thomas Ernst Ulf Schnetzke Andreas Hochhaus Paul La Ros ée Sebastian Birndt Source Type: research