Effects of Opioids, Steroids, Benzodiazepines, Anticholinergics, and Antihistamines on the Efficacy of Antipsychotics for Treating Delirium in End-of-Life Adult Patients Undergoing Palliative Care
J Pain Palliat Care Pharmacother. 2023 Sep 13:1-10. doi: 10.1080/15360288.2023.2253241. Online ahead of print.ABSTRACTThe purpose of the study was to determine the effect of combination therapy involving opioids, steroids, benzodiazepines, anticholinergics, and antihistamines on antipsychotics efficacy for delirium. The study included adult inpatients receiving end-of-life palliative care and diagnosed with hyperactive delirium. Changes in delirium symptoms were assessed using the Intensive Care Delirium Screening Checklist (ICDSC). A retrospective analysis was conducted on 97 patients with ICDSC scores of ≥4, comparing ...
Source: Journal of Pain and Palliative Care Pharmacotherapy - September 13, 2023 Category: Palliative Care Authors: Junya Sato Rei Tanaka Source Type: research

Oxycodone Extended-Release Capsule Utilization for Pain Management in  a Cancer Palliative Care Clinic: A Retrospective Review
J Pain Palliat Care Pharmacother. 2023 Sep 13:1-12. doi: 10.1080/15360288.2023.2253248. Online ahead of print.ABSTRACTABSTRACT Xtampza ER™, an oxycodone extended-release capsule (OERC), was the first long-acting opioid to feature abuse-deterrent properties and various routes of administration without pharmacokinetic alterations. The primary objective of this study was to evaluate changes in reported pain scores after initiation of or rotation to OERC from a previous opioid. Baseline scores were from patients' outpatient visits immediately before starting OERC and were compared to those at the next two follow-up visits. S...
Source: Journal of Pain and Palliative Care Pharmacotherapy - September 13, 2023 Category: Palliative Care Authors: Jordan Fortunato Justin Kullgren Gary Houchard Jessica Hirsch Nicole Shirilla Meridith Bumb Junan Li Source Type: research

Oxygen Therapy in the Last Days and Hours of Life: From Evidence to Practice
J Pain Palliat Care Pharmacother. 2023 Sep 7:1-2. doi: 10.1080/15360288.2023.2250332. Online ahead of print.NO ABSTRACTPMID:37676717 | DOI:10.1080/15360288.2023.2250332 (Source: Journal of Pain and Palliative Care Pharmacotherapy)
Source: Journal of Pain and Palliative Care Pharmacotherapy - September 7, 2023 Category: Palliative Care Authors: M ónica Carqueijó Source Type: research

Comparing Post-operative Opioid Consumption before and after a Patient-Controlled Analgesia Shortage: A Re-evaluation of Safety and Effectiveness
J Pain Palliat Care Pharmacother. 2023 Sep 5:1-6. doi: 10.1080/15360288.2023.2250334. Online ahead of print.ABSTRACTThis retrospective cohort study aimed to compare post-surgical opioid consumption before and after a PCA (patient-controlled analgesia) shortage. The study evaluated patients who received PCA vs. nurse-administered opioid analgesia (non-PCA). Two hundred and twenty-four patients ≥18 years who were initiated on analgesia within 24 h of surgery were included. The primary outcome was opioid consumption in average daily oral morphine milliequivalents (MME). The results showed that patients in the PCA group had ...
Source: Journal of Pain and Palliative Care Pharmacotherapy - September 5, 2023 Category: Palliative Care Authors: Lena Zoma Renee Alexander Paxton Michelle Dehoorne Christopher Giuliano Source Type: research

Mpox Pain Management with Topical Agents: A Case Series
We present two patients' painful experiences with Monkeypox and suggest lessons learned.PMID:37651724 | DOI:10.1080/15360288.2023.2250762 (Source: Journal of Pain and Palliative Care Pharmacotherapy)
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 31, 2023 Category: Palliative Care Authors: Mariam Shabbir Maria Lorraine Bugayong Michael Anthony DeVita Source Type: research

Suspected Buprenorphine-Precipitated Opioid Withdrawal following Intercourse: A Case Report
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-3. doi: 10.1080/15360288.2023.2250344. Online ahead of print.ABSTRACTBuprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known about the pharmacokinetics of drugs in seminal fluid, pH is thought to play an integral role. Limited evidence exists surrounding cervical absorption of drugs via seminal fluid transmission. This also prompts survey...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Davene Lynch Lyndsey Chitty Brittany Johnson Amie L Hoefnagel Source Type: research