Review of Dopamine Antagonists for Nausea and Vomiting in Palliative Care Patients
J Pain Palliat Care Pharmacother. 2023 Oct 16:1-7. doi: 10.1080/15360288.2023.2268065. Online ahead of print.ABSTRACTSymptoms of nausea and vomiting are common in palliative care and hospice patients. One of the many classes of medications used for the treatment of nausea and vomiting is dopamine receptor antagonists which are particularly helpful for treating nausea mediated by the chemoreceptor trigger zone (CTZ) and impaired gastrointestinal function. While dopamine antagonists can be very effective treatments for nausea they should be used with caution as they carry the risk of QTc prolongation, have a FDA black box wa...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 16, 2023 Category: Palliative Care Authors: Grace Jenkins Source Type: research

Atypical Withdrawal Symptoms after Abrupt Tramadol Discontinuation: A Case Report
J Pain Palliat Care Pharmacother. 2023 Oct 4:1-3. doi: 10.1080/15360288.2023.2261913. Online ahead of print.ABSTRACTTramadol is a commonly utilized analgesic in the United States. One common misconception is that tramadol is safer than other opioid medications, or less likely to cause physical dependence. Given these misconceptions, the likelihood of patients experiencing withdrawal after discontinuation may be commonly overlooked as well. A 68-year old female patient with fibromyalgia was referred to a clinical pharmacy pain clinic for medication management. The patient was evaluated one month after abrupt discontinuation...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 4, 2023 Category: Palliative Care Authors: Caylee Sams Serena Cheng Source Type: research

Systematic Review on Barriers to Access Opioid Analgesics for Cancer Pain Management from the Health Worker Perspective
J Pain Palliat Care Pharmacother. 2023 Sep 29:1-12. doi: 10.1080/15360288.2023.2257674. Online ahead of print.ABSTRACTThe increasing incidence of oncological diseases creates a corresponding need for effective cancer pain management (CPM). The lack of access to and availability of opioid analgesics in most countries leads to avoidable suffering. This systematic review aims to identify barriers to accessing opioids, as described in literature that reflects the perspective of health-care workers. A systematic literature search was performed in May 2018 and updated in December 2022, using search terms related to "cancer pain,...
Source: Journal of Pain and Palliative Care Pharmacotherapy - September 29, 2023 Category: Palliative Care Authors: Josephine Fleckner Katherine Pettus Nandini Vallath Tania Pastrana Source Type: research