Does student evaluation of on-demand video lectures vary with student characteristics? A questionnaire survey of medical students at Tokushima University
This study aims to examine the association between the detailed characteristics/various contexts of students and the evaluation of online classes. An online questionnaire survey administered to third- and fourth-grade medical students of Tokushima University in September 2021-with 101 (42.8%) valid responses-showed the respondents' general impressions, comprehension, convenience, and desire for online classes even after the pandemic ends were significantly higher for the on-demand lectures than for simultaneous online classes. Notably, students who did not do other things while watching video lectures (10.9%) rated on-dema...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Harutaka Yamaguchi Seito Kagoshima Yoshihiro Okura Yoshinori Nakanishi Keisuke Kawahito Kenji Tani Source Type: research
Prognosis of frail older patients treated with intubation and artificial ventilation for respiratory failure
CONCLUSION: The overall prognosis of frail older patients who underwent intubation and artificial ventilation was poor. When providing intensive care to such patients, it is important to carefully consider their suitability for the treatment. J. Med. Invest. 70 : 494-498, August, 2023.PMID:37940537 | DOI:10.2152/jmi.70.494 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Kazuhisa Nakashima Ken Yoshihara Kento Kono Mika Horie Seiko Tanaka Keita Kawakado Misato Kobayashi Yohei Shiratsuki Takae Okuno Mika Nakao Yoshihiro Amano Takamasa Hotta Megumi Hamaguchi Shunichi Hamaguchi Yukari Tsubata Taishi Nagao Noriaki Kurimoto Tak Source Type: research
Suspected Aspergillus nodule histologically consistent with pulmonary nodular lymphoid hyperplasia:a case report
J Med Invest. 2023;70(3.4):499-502. doi: 10.2152/jmi.70.499.ABSTRACTAspergillus nodules (AN) are an unusual form of chronic pulmonary aspergillosis. On the other hand, pulmonary nodular lymphoid hyperplasia (PNLH) is classified as a reactive pulmonary lymphoproliferative disorder. A 65-year-old male was referred to our hospital due to a nodule in the left upper lobe. Histologically, a mixture of prominent lymphoid follicular formation, and hyaline necrosis were observed. Grocott staining revealed morphological forms of Aspergillus spp. in the necrosis. The final clinical diagnosis was suspected AN histologically consistent...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Shun Morizumi Atsushi Morishita Miho Nishiyama Kiyohide Takahashi Kenya Sumitomo Hiroyuki Hino Keishi Naruse Eiji Takeuchi Shoji Sakiyama Tsutomu Shinohara Source Type: research
An incidentally discovered paraganglioma that caused sinus arrest after resection
J Med Invest. 2023;70(3.4):503-507. doi: 10.2152/jmi.70.503.ABSTRACTParagangliomas are neural-crest-derived nonepithelial neuroendocrine tumors distributed along the parasympathetic and sympathetic nerves. To our knowledge, no studies were reported regarding sinus arrest on day 4 after paraganglioma resection. A 66-year-old female patient with a history of pulmonary vein isolation visited our department for sigmoid colon cancer treatment. Enhanced computed tomography revealed an enhanced small nodule-like lymph node near the root of the inferior mesenteric artery. The patient underwent laparoscopic colectomy with regional ...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Takayuki Sano Takeshi Inoue Naoko Irie Tatsuo Ichikawa Akira Iai Kiyoshi Osa Satoshi Ono Kozo Asanuma Shiori Kaneko Tadao Kuribara Itaru Shigeyoshi Kouta Matsubara Kanako Suzuki Hideki Ishizu Keishin Sunagawa Source Type: research
A rare case of massive hepatic abscess 6 years after ERCP due to retained biliary stent
CONCLUSION: The insertion of biliary stents is common endoscopic technique, but close follow up is of outmost importance. J. Med. Invest. 70 : 508-512, August, 2023.PMID:37940540 | DOI:10.2152/jmi.70.508 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Ioannis G Gkionis Michail I Giakoumakis Ifigenia Tzartzalou George Kavallaris Pinelopi Nicolaou Emmanouil Vardas Aggelos Laliotis Source Type: research
Primary leiomyoma of the bladder radiologically mimicking a retroperitoneal tumor - a case report
J Med Invest. 2023;70(3.4):513-515. doi: 10.2152/jmi.70.513.ABSTRACTThe case presented is of a 47-year-old patient with an extravesical pedunculated bladder leiomyoma, which was difficult to distinguish from a retroperitoneal tumor. Preoperatively, it was suspected to be a retroperitoneal tumor and a laparotomy with tumor resection was performed. lntraoperatively, the bladder and tumor were connected by a cord-like tissue. A retrospective review of preoperative images revealed that cord-like tissue, identified intraoperatively, was also present. Bladder leiomyomas can grow as extravesical pedunculated tumors. Therefore, wh...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Mami Taniuchi Masato Yanagi Tomonari Kiriyama Jun Akatsuka Hiroya Hasegawa Hikaru Mikami Yuki Endo Hayato Takeda Yuka Toyama Go Kimura Yukihiro Kondo Source Type: research
A case of successful treatment with eltrombopag for severe immune-related thrombocytopenia induced by atezolizumab:Case report
J Med Invest. 2023;70(3.4):516-520. doi: 10.2152/jmi.70.516.ABSTRACTImmune checkpoint inhibitors (ICIs) have shown impressive anti-tumor effects against multiple types of malignancies. Among the wide variety of immune-related adverse events (irAEs), immune-related thrombocytopenia (ITP) is relatively rare but often clinically significant and life-threatening. However, the appropriate treatment for severe ITP has not been determined. We herein report an 82-year-old male patient with non-small-cell lung cancer who developed severe ITP three weeks after starting the third course of atezolizumab. The initial combination therap...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Saki Harada Takeshi Imakura Seidai Sato Hiroshi Nokihara Yasuhiko Nishioka Source Type: research
Repeated shunt dysfunction due to Barium allergy that was difficult to differentiate from shunt infection
J Med Invest. 2023;70(3.4):521-523. doi: 10.2152/jmi.70.521.ABSTRACTWe encountered a case of repeated shunt dysfunction caused by barium allergy. The patient was a 60-year-old male who underwent ventricular peritoneal shunting for hydrocephalus following subarachnoid hemorrhage due to a ruptured aneurysm;however, it malfunctioned many times. A patch test performed after the third reconstruction was positive for barium. To the best of our knowledge, this is the first case report of shunt malfunction due to barium allergy. The patch test is useful in cases of suspected allergy-related dysfunction. We recommend the introducti...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Asami Kikuchi Shigeomi Yokoya Hideki Oka Hiroshi Ohno Akihiko Hino Source Type: research
A novel computed tomography-based three-column MLP classification of intertrochanteric fracture
CONCLUSION: This novel 3DCT-based MLP classification system for intertrochanteric fractures is comprehensive, and reproducible with good agreement. It is based on proximal femur biomechanic characteristics and traumatic mechanism, contributing to formulating more reasonable treatment protocols involving various late-model internal fixation devices. J. Med. Invest. 70 : 524-529, August, 2023.PMID:37940544 | DOI:10.2152/jmi.70.524 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Qi-Long Jiang Yan Li Xin-Wen Bai Yu Deng Hao Hong Jun Li Yong Cao Xiao-Yu Peng Source Type: research
Technologies, Physician's Caring Competency, and Patient Centered Care:A Systematic Review
This study aimed to conduct a systematic review to clarify patient understanding, understanding of caring concepts, understanding of technology, competency to express compassion, appropriate involvement in caring, and ethical and moral attitudes and responses toward patients. This systematic review was conducted through an electronic search across PubMed, Google Scholar, MEDLINE, and Science Direct. Authors independently appraised the methodological quality of the studies using the Mixed Method Appraisal Tool. A narrative synthesis approach was used to present these findings. Nine studies met the inclusion criteria and qua...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Leah Anne Christine L Bollos Yueren Zhao Gil P Soriano Tetsuya Tanioka Hideki Otsuka Rozzano Locsin Source Type: research
Immune response evaluation after Sputnik V vaccination in Sari healthcare population
CONCLUSION: Sputnik V vaccine can lead to a protective response against COVID-19 infection in high percentage of the population. J. Med. Invest. 70 : 317-320, August, 2023.PMID:37940513 | DOI:10.2152/jmi.70.317 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Ahmad Najafi Hossien Jalali Yousef Noshi Mehrad Mahdavi Mohammad Reza Mahdavi Amiri Source Type: research
Effects of activation with a Ca ionophore and roscovitine on the development of human oocytes that failed to fertilize after ICSI
CONCLUSIONS: Sequential treatment with an Ca ionophore and roscovitine activates oocytes that remain unfertilized after ICSI. In TESE-ICSI, the activation rate tended to be increased by the co-administration of roscovitine with a Ca ionophore. J. Med. Invest. 70 : 321-324, August, 2023.PMID:37940514 | DOI:10.2152/jmi.70.321 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Ayako Suto Yuya Yano Yuri Yamamoto Hiroki Noguchi Asuka Takeda Shota Yamamoto Tomohiro Kagawa Kanako Yoshida Kenji Hinokio Akira Kuwahara Toshiyuki Yasui Takeshi Iwasa Source Type: research
Early enteral nutrition with arginine compensates for negative nitrogen balance in patients undergoing curative total gastrectomy
J Med Invest. 2023;70(3.4):325-333. doi: 10.2152/jmi.70.325.ABSTRACTThe effects of early enteral arginine-rich nutrition (EAN) were analyzed among patients undergoing curative-intent total gastrectomy for gastric cancer. There were 19 patients in this prospective study, all randomly assigned to either a parenteral nutrition (PN) group or an EAN group for the first seven days after surgery. The EAN group received 1.8-fold greater arginine (10.1 g/day) compared with the PN group, which was administered through an enteral tube inserted into the jejunal loop. Both groups were provided almost identical amounts of total amino ac...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Yasuko Okamoto Takanori Sakaguchi Yoshito Ikematsu Toshikazu Kanai Kazuhisa Hirayama Hiroaki Tamura Tadataka Hayashi Yoshiro Nishiwaki Hiroyuki Konno Katsunori Aoki Source Type: research
A comparison of reoperation rates after single-level anterior cervical discectomy and fusion (ACDF) between the procedures with and without anterior plate fixation
CONCLUSION: Anterior cervical plating may have a negative impact on the adjacent segment integrity, resulting in an increased reoperation rate after a single-level ACDF at relatively shorter postoperative time points. J. Med. Invest. 70 : 334-342, August, 2023.PMID:37940516 | DOI:10.2152/jmi.70.334 (Source: Journal of Medical Investigation)
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Nobuaki Tadokoro Katsuhito Kiyasu Naoki Aoyama Shuhei Mizobuchi Masahiko Ikeuchi Kazunobu Kida Toshikazu Tani Yusuke Kasai Source Type: research
Role of Nrf2 signaling in development of hepatocyte-like cells
In this study, we investigated the activation of the nuclear factor erythroid-2 related factor 2 (Nrf2) on hADSCs undergoing differentiation to HLC (hepatocyte-like cells). Our three-step differentiation protocol was applied for 21 days (Step 1:day 1-6, Step2:day 6-11, Step3:day 11-21). Our results show that significant nuclear translocation of Nrf2 occurred from day 11 until the end of HLC differentiation. Nuclear translocation of Nrf2 and CYP3A4 activity in the GSK3 inhibitor-treated group was obviously higher than that in Activin A-treated groups at day 11. The maturation of HLCs was delayed in Nrf2-siRNA group compared...
Source: Journal of Medical Investigation - November 8, 2023 Category: General Medicine Authors: Chie Takasu Shuhai Chen Luping Gao Yu Saito Yuji Morine Tetsuya Ikemoto Shinichiro Yamada Mitsu Shimad Source Type: research
