Journal of Cell Communication and Signaling 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.GREM1 signaling in cancer: tumor promotor and suppressor?
J Cell Commun Signal. 2023 Aug 24. doi: 10.1007/s12079-023-00777-4. Online ahead of print.ABSTRACTGREMLIN1 (GREM1) is member of a family of structurally and functionally related secreted cysteine knot proteins, which act to sequester and inhibit the action of multifunctional bone morphogenetic proteins (BMPs). GREM1 binds directly to BMP dimers, thereby preventing BMP-mediated activation of BMP type I and type II receptors. Multiple reports identify the overexpression of GREM1 as a contributing factor in a broad range of cancers. Additionally, the GREM1 gene is amplified in a rare autosomal dominant inherited form of color...
Source: Journal of Cell Communication and Signaling - August 24, 2023 Category: Molecular Biology Authors: Zhichun Gao Julia M Houthuijzen Peter Ten Dijke Derek P Brazil Source Type: research
GREM1 signaling in cancer: tumor promotor and suppressor?
J Cell Commun Signal. 2023 Aug 24. doi: 10.1007/s12079-023-00777-4. Online ahead of print.ABSTRACTGREMLIN1 (GREM1) is member of a family of structurally and functionally related secreted cysteine knot proteins, which act to sequester and inhibit the action of multifunctional bone morphogenetic proteins (BMPs). GREM1 binds directly to BMP dimers, thereby preventing BMP-mediated activation of BMP type I and type II receptors. Multiple reports identify the overexpression of GREM1 as a contributing factor in a broad range of cancers. Additionally, the GREM1 gene is amplified in a rare autosomal dominant inherited form of color...
Source: Journal of Cell Communication and Signaling - August 24, 2023 Category: Molecular Biology Authors: Zhichun Gao Julia M Houthuijzen Peter Ten Dijke Derek P Brazil Source Type: research
GREM1 signaling in cancer: tumor promotor and suppressor?
J Cell Commun Signal. 2023 Aug 24. doi: 10.1007/s12079-023-00777-4. Online ahead of print.ABSTRACTGREMLIN1 (GREM1) is member of a family of structurally and functionally related secreted cysteine knot proteins, which act to sequester and inhibit the action of multifunctional bone morphogenetic proteins (BMPs). GREM1 binds directly to BMP dimers, thereby preventing BMP-mediated activation of BMP type I and type II receptors. Multiple reports identify the overexpression of GREM1 as a contributing factor in a broad range of cancers. Additionally, the GREM1 gene is amplified in a rare autosomal dominant inherited form of color...
Source: Journal of Cell Communication and Signaling - August 24, 2023 Category: Molecular Biology Authors: Zhichun Gao Julia M Houthuijzen Peter Ten Dijke Derek P Brazil Source Type: research
GREM1 signaling in cancer: tumor promotor and suppressor?
J Cell Commun Signal. 2023 Aug 24. doi: 10.1007/s12079-023-00777-4. Online ahead of print.ABSTRACTGREMLIN1 (GREM1) is member of a family of structurally and functionally related secreted cysteine knot proteins, which act to sequester and inhibit the action of multifunctional bone morphogenetic proteins (BMPs). GREM1 binds directly to BMP dimers, thereby preventing BMP-mediated activation of BMP type I and type II receptors. Multiple reports identify the overexpression of GREM1 as a contributing factor in a broad range of cancers. Additionally, the GREM1 gene is amplified in a rare autosomal dominant inherited form of color...
Source: Journal of Cell Communication and Signaling - August 24, 2023 Category: Molecular Biology Authors: Zhichun Gao Julia M Houthuijzen Peter Ten Dijke Derek P Brazil Source Type: research
GREM1 signaling in cancer: tumor promotor and suppressor?
J Cell Commun Signal. 2023 Aug 24. doi: 10.1007/s12079-023-00777-4. Online ahead of print.ABSTRACTGREMLIN1 (GREM1) is member of a family of structurally and functionally related secreted cysteine knot proteins, which act to sequester and inhibit the action of multifunctional bone morphogenetic proteins (BMPs). GREM1 binds directly to BMP dimers, thereby preventing BMP-mediated activation of BMP type I and type II receptors. Multiple reports identify the overexpression of GREM1 as a contributing factor in a broad range of cancers. Additionally, the GREM1 gene is amplified in a rare autosomal dominant inherited form of color...
Source: Journal of Cell Communication and Signaling - August 24, 2023 Category: Molecular Biology Authors: Zhichun Gao Julia M Houthuijzen Peter Ten Dijke Derek P Brazil Source Type: research
