Clinical significance and different strategies for re-elevation of plasma EBV-DNA during treatment in pediatric EBV-associated hemophagocytic lymphohistiocytosis
CONCLUSION: The re-elevation of plasma EBV-DNA during EBV-HLH treatment poses challenges in determining disease status and treatment strategies. Optimal management decisions require a combination of the level of elevated EBV-DNA, the intensity of hyperinflammation, and the patient's immune function.PMID:38604242 | DOI:10.1016/j.jped.2024.03.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 11, 2024 Category: Pediatrics Authors: Wenzhi Zhang Yun Peng Yining Qiu Li Cheng Yuhong Yin Ying Li Lizhen Zhao Xiaoyan Wu Source Type: research
Key clinical predictors in the diagnosis of ovarian torsion in children
CONCLUSION: This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.PMID:38582497 | DOI:10.1016/j.jped.2024.01.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 6, 2024 Category: Pediatrics Authors: Sai Chen Zhigang Gao Yunzhong Qian Qingjiang Chen Source Type: research
Key clinical predictors in the diagnosis of ovarian torsion in children
CONCLUSION: This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.PMID:38582497 | DOI:10.1016/j.jped.2024.01.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 6, 2024 Category: Pediatrics Authors: Sai Chen Zhigang Gao Yunzhong Qian Qingjiang Chen Source Type: research
Key clinical predictors in the diagnosis of ovarian torsion in children
CONCLUSION: This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.PMID:38582497 | DOI:10.1016/j.jped.2024.01.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 6, 2024 Category: Pediatrics Authors: Sai Chen Zhigang Gao Yunzhong Qian Qingjiang Chen Source Type: research
Key clinical predictors in the diagnosis of ovarian torsion in children
CONCLUSION: This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.PMID:38582497 | DOI:10.1016/j.jped.2024.01.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 6, 2024 Category: Pediatrics Authors: Sai Chen Zhigang Gao Yunzhong Qian Qingjiang Chen Source Type: research
Key clinical predictors in the diagnosis of ovarian torsion in children
CONCLUSION: This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.PMID:38582497 | DOI:10.1016/j.jped.2024.01.006 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 6, 2024 Category: Pediatrics Authors: Sai Chen Zhigang Gao Yunzhong Qian Qingjiang Chen Source Type: research
Substance use and adolescent mental health during the COVID-19 pandemic in Brazil: a longitudinal approach
CONCLUSIONS: Despite the extensive decline in substance use during the pandemic period, these results suggest an association between previous mental health conditions and behavioral risk factors, leading to increased alcohol consumption and behavioral disorders manifestations.PMID:38580211 | DOI:10.1016/j.jped.2024.01.005 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 5, 2024 Category: Pediatrics Authors: Rodrigo Garcia-Cerde Gabriela A Wagner Juliana Y Valente Zila M Sanchez Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study
CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research
Use of dietary supplements by children and adolescents
CONCLUSION: Despite having specific indications, most of the time they are not prescribed by a healthcare professional. The reasons for use are varied. In children, the main reasons are protection against infections, stimulating growth, and poor food intake, with multivitamins and minerals being the most commonly used supplements. In adolescents, they are used to improve athletic performance and attain the "ideal body", with proteins and amino acids being the most often used nutrients. As they are not regulated by health agencies and are sold without a prescription, their unsupervised use can lead to inadequate doses, with...
Source: Jornal de Pediatria - March 26, 2024 Category: Pediatrics Authors: Junaura Rocha Barretto Mara Alves da Cruz Gouveia Cr ésio Alves Source Type: research
