Inborn errors of immunity and its clinical significance in children with lymphoma in China: a single-center study

CONCLUSION: The present study demonstrated that IEI-associated lymphomas were much more common than originally appreciated in pediatric lymphomas, and those were insensitive to treatment and more likely to progress or relapse. The genomic analysis and a thorough review of the medical history of IEI can be used to distinguish them from pediatric lymphomas without IEI, which are beneficial for the early diagnosis and direct intervention.PMID:38547930 | DOI:10.1016/j.jped.2024.02.002

Source: Jornal de Pediatria - March 28, 2024 Category: Pediatrics Authors: Chao Yang Nan Li Meng Zhang Shuang Huang Ling Jin Shu-Guang Liu Chun-Ju Zhou Zhi-Gang Li Yan-Long Duan Source Type: research