International Journal of Medical Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Prediction of outcomes for rescue cerclage in cervical insufficiency: A multicenter retrospective study
Conclusion: The developed logistic regression models offer a valuable tool for the prognostic assessment of patients undergoing rescue cerclage, enabling informed clinical decision-making.PMID:38617007 | PMC:PMC11008492 | DOI:10.7150/ijms.87941 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Subeen Hong Hyun Sik Chung Sujin Choi Yun Sung Jo Source Type: research

Hidradenitis suppurativa as a potential risk factor of periodontitis: a multi-center, propensity-score-matched cohort study
Conclusion: The observed increased risk suggests the need for heightened awareness and potential interdisciplinary care for individuals with HS to address periodontal health.PMID:38617008 | PMC:PMC11008474 | DOI:10.7150/ijms.93178 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Shuo-Yan Gau Yu-Chen Guo Hsin-Yo Lu Chen-Yu Lin Chien-Ying Lee Ru-Yin Tsai Hui-Chin Chang Meng-Che Wu Chen-Pi Li Source Type: research

Protective Effect of Fermented Sea Tangle Extract on Skin Cell Damage Caused by Particulate Matter
Int J Med Sci. 2024 Mar 31;21(5):937-948. doi: 10.7150/ijms.93034. eCollection 2024.ABSTRACTThe skin is directly exposed to atmospheric pollutants, especially particulate matter 2.5 (PM2.5) in the air, which poses significant harm to skin health. However, limited research has been performed to identify molecules that can confer resistance to such substances. Herein, we analyzed the effect of fermented sea tangle (FST) extract on PM2.5-induced human HaCaT keratinocyte damage. Results showed that FST extract, at concentrations less than 800 μg/mL, exhibited non-significant toxicity to cells and concentration-dependent inhib...
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Mei Jing Piao Kyoung Ah Kang Pincha Devage Sameera Madushan Fernando Herath Mudiyanselage Udari Lakmini Herath Young Sang Koh Hee Kyoung Kang Yung Hyun Choi Jin Won Hyun Source Type: research

Biomarker Potential of < em > LINC00313 < /em > in Head and Neck Squamous Cell Carcinoma: Correlation with Epithelial-Mesenchymal Transition and Immune Cell Infiltration
In conclusion, LINC00313 is a potential biomarker of HNSC prognosis and a potential target for immunotherapy.PMID:38617010 | PMC:PMC11008489 | DOI:10.7150/ijms.93044 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yikun Ju Fang Zhu Bairong Fang Source Type: research

Role of mitochondria in doxorubicin-mediated cardiotoxicity: from molecular mechanisms to therapeutic strategies
In conclusion, this review offers valuable insights into the intricate relationship between mitochondrial dysfunction and doxorubicin-mediated cardiotoxicity. It underscores the need for continued research into targeted mitochondrial therapies as a means to improve the cardiac safety profile of doxorubicin, thereby enhancing the overall treatment outcomes for cancer patients.PMID:38617011 | PMC:PMC11008476 | DOI:10.7150/ijms.94485 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Tianen Wang Guoli Xing Tong Fu Yanchun Ma Qi Wang Shuxiang Zhang Xing Chang Ying Tong Source Type: research

High-Flow Nasal Oxygen versus Conventional Nasal Cannula in Preventing Hypoxemia in Elderly Patients Undergoing Gastroscopy with Sedation: A Randomized Controlled Trial
Conclusions: The HFNO system was determined to be a safe and highly effective method for oxygen delivery, leading to a reduction in the occurrence of hypoxemia in elderly patients undergoing gastroscopy with sedation. It is recommended that HFNO be considered as the standard approach for management in this population.PMID:38617012 | PMC:PMC11008486 | DOI:10.7150/ijms.91607 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Xin Yin Wen Xu Jianlei Zhang Mingyue Wang Zhen Chen Songbin Liu Yan Xu Shaowen Xu Danian Ji Jingwen Wang Weidong Gu Source Type: research

Evaluating Novel SP-B and SP-C Synthetic Analogues for Pulmonary Surfactant Efficacy
This study's findings support the potential of CHAsurf-4B as a therapeutic agent, meriting further investigation to solidify its role in clinical applications.PMID:38617013 | PMC:PMC11008487 | DOI:10.7150/ijms.92920 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Chae Young Kim Sung-Hoon Chung Yong Sung Choi Kyeong-Yong Park Chong-Woo Bae Source Type: research

Respiratory pathogenic microbial infections: a narrative review
This article aims to review community-acquired respiratory illnesses covering a broad spectrum of viruses, bacteria, and atypical microorganisms and focuses on the cluster prevalence of multiple known respiratory pathogens in China, thereby providing effective prevention and control measures.PMID:38617014 | PMC:PMC11008481 | DOI:10.7150/ijms.93628 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yiyin Long Yan Zheng Changlin Li Zhanjun Guo Peng Li Fuqing Zhang Wei Liu Yuliang Wang Source Type: research

The crucial relationship between miRNA-27 and CSE/H < sub > 2 < /sub > S, and the mechanism of action of GLP-1 in myocardial hypertrophy
In this study, we aimed to investigate whether inhibition of miR-27a could protect against cardiac hypertrophy by modulating H2S signaling. We established a model of cardiac hypertrophy by obtaining hypertrophic tissue from mice subjected to transverse aortic constriction (TAC) and from cells treated with angiotensin-II. Molecular alterations in the myocardium were quantified using quantitative real time PCR (qRT-PCR), Western blotting, and ELISA. Morphological changes were characterized by hematoxylin and eosin (HE) staining and Masson's trichrome staining. Functional myocardial changes were assessed using echocardiograph...
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Shan Gao Ying Li Mei-Ming Liu Xue Xiong Chang-Peng Cui Qing-Ji Huo Ke-Xin Li Xun Sun Rong Zhang Di Wu Bai-Yan Li Source Type: research

The Outcomes of Patients with Omicron Variant Infection who Undergo Elective Surgery: A Propensity-score-matched Case-control Study
Conclusion: Omicron infection does not significantly increase the risk of perioperative major complications. The Omicron infection may not be a sufficient risk factor to postpone elective surgery.PMID:38616997 | PMC:PMC11008485 | DOI:10.7150/ijms.90695 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Xiaojuan Xiong Rui Li Hong Yan Qingxiang Mao Source Type: research

Depression risk in chronic tonsillitis patients underwent tonsillectomy: a global federated health network analysis
Conclusion: This real-world analysis found tonsillectomy was associated with a 30% higher 5-year depression risk versus matched non-tonsillectomy patients with chronic tonsillitis. Further mechanistic research is needed to clarify the pathophysiologic association between depression and tonsillectomy. Depression is not commonly mentioned in the current post-tonsillectomy care realm; however, the outcome of our study emphasized the possibility of these suffering condition after operation. Attention to psychological impacts following tonsillectomy is warranted to support patient well-being, leading to better management of pos...
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Hui-Chin Chang Hsin-Yo Lu Yu-Chen Guo Chen-Yu Lin Shiu-Jau Chen Shuo-Yan Gau Source Type: research

The Expression and Prognostic Significance of ICOS in NSCLC Integrated Pan-Cancer and Multi-Omics Analyses
Conclusion: Our findings support that ICOS suggests lower pathological staging and better prognosis. ICOS is a potential diagnostic and prognostic biomarker for NSCLC.PMID:38616999 | PMC:PMC11008490 | DOI:10.7150/ijms.93262 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Mengting Chen Xiaotian Yan Bo Hong Yufei Xiao Yun Qian Source Type: research

A chronic stress-induced microbiome perturbation, highly enriched in < em > Ruminococcaceae_UCG-014 < /em > , promotes colorectal cancer growth and metastasis
Conclusion: CRS exposure altered diversity, composition and metabolites of the gut microbiome, with Ruminococcaceae_UCG-014 perturbation consistently correlated to inflammatory responses, suggesting a particular role of this bacterial genus in CRC growth and metastasis.PMID:38617000 | PMC:PMC11008488 | DOI:10.7150/ijms.90612 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Ling Zhao Xinxin Hou Yuanyuan Feng Yingru Zhang Shiyun Shao Xinnan Wu Junfeng Jim Zhang Zhaozhou Zhang Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Natural Product Quercetin-3-methyl ether Promotes Colorectal Cancer Cell Apoptosis by Downregulating Intracellular Polyamine Signaling
Int J Med Sci. 2024 Mar 25;21(5):904-913. doi: 10.7150/ijms.93903. eCollection 2024.ABSTRACTDysregulation of cellular metabolism is a key marker of cancer, and it is suggested that metabolism should be considered as a targeted weakness of colorectal cancer. Increased polyamine metabolism is a common metabolic change in tumors. Thus, targeting polyamine metabolism for anticancer therapy, particularly polyamine blockade therapy, has gradually become a hot topic. Quercetin-3-methyl ether is a natural compound existed in various plants with diverse biological activities like antioxidant and antiaging. Here, we reported that Qu...
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jincheng Zeng Yuancheng Zhang Yuming Fang Jiachun Lian Hailiang Zhang Shaobing Zhang Bihua Lin Ziyu Ye Caihong Li Xianxiu Qiu Yanfang Liang Source Type: research