Skin Cell and Tissue Responses to Cross-Linked Hyaluronic Acid in Low-Grade Inflammatory Conditions
Int J Inflam. 2023 Aug 26;2023:3001080. doi: 10.1155/2023/3001080. eCollection 2023.ABSTRACTHyaluronic acid (HA), used in a variety of medical applications, is associated in rare instances to long-term adverse effects. Although the aetiology of these events is unknown, a number of hypotheses have been proposed, including low molecular weight of HA (LMW-HA) in the filler products. We hypothesized that cross-linked HA and its degradation products, in a low-grade inflammatory microenvironment, could impact immune responses that could affect cell behaviours in the dermis. Using two different cross-linking technologies VYC-15L ...
Source: International Journal of Inflammation - September 4, 2023 Category: Allergy & Immunology Authors: Benjamin Sanchez Sandra Ferraro Audrey Josset-Lamaugarny Aur élie Pagnon Charlie K Hee Lauren Nakab Dominique Sigaudo-Roussel B érengère Fromy Source Type: research