International Journal of Inflammation This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Differentially Expressed Genes Analysis in the Human Small Airway Epithelium of Healthy Smokers Shows Potential Risks of Disease Caused by Oxidative Stress and Inflammation and the Potentiality of Astaxanthin as an Anti-Inflammatory Agent
This study aims to observe differentially expressed genes (DEGs) in the human small airway epithelium of smokers compared to genes whose expression changes due to astaxanthin (AST) treatment, an antioxidant compound that can modulate Nrf2. Gene expression data that was stored in the GEO browser (GSE 11952) was analyzed using GEO2R to search for DEG among smokers and nonsmokers subject. DEG was further compared to those genes whose expression changes due to astaxanthin treatment (AST) that were obtained from the Comparative Toxicogenomics Database (CTD; https://ctdbase.org/). DEG (p < 0.05) analysis result shows that the...
Source: International Journal of Inflammation - March 13, 2023 Category: Allergy & Immunology Authors: Irandi Putra Pratomo Aryo Tedjo Dimas R Noor None Rosmalena Source Type: research

 In Vitro and In Vivo Anti-Inflammatory Properties of the Hydroethanolic Extract of the Roots of Vernonia guineensis (Asteraceae)
This study considered the evaluation of acute toxicity and anti-inflammatory properties of the hydroethanolic extract of the roots of Vernonia guineensis. In an acute toxicity study, 250, 2500, and 5000 mg/kg were administered orally to mice in a single dose, and general behavior, adverse effects, and mortality were monitored. In vitro and in vivo anti-inflammatory tests were performed, and then histological, serum, hematological, and oxidative stress parameters have been evaluated. In an acute toxicity, all groups revealed neither mortality nor any significant alteration in behavior; only drowsiness, sedation, and letharg...
Source: International Journal of Inflammation - March 13, 2023 Category: Allergy & Immunology Authors: William Yousseu Nana Justin Rodrigue Billong Mimb Albert Donatien Atsamo Eric Gonzal Tsafack Stephanie Flore Djuichou Nguemnang Zenab Linda Fagni Njoya Vanessa Mba Matah Marthe Yacine Karelle Madjo Kouam Marius Mbiantcha Gilbert Ateufack Source Type: research

The Restoring Effect of Human Umbilical Cord-Derived Mesenchymal Cell-Conditioned Medium (hMSC-CM) against Carbon Tetrachloride-Induced Pulmonary Fibrosis in Male Wistar Rats
CONCLUSION: hMSC-MSC as a strong anti-inflammatory, antioxidative, and antifibrotic decreases the level of oxidative stress, proinflammatory cytokines, and MDA causing a restoring effect against CCl4-induced pulmonary fibrosis.PMID:36588784 | PMC:PMC9800074 | DOI:10.1155/2022/7179766 (Source: International Journal of Inflammation)
Source: International Journal of Inflammation - January 2, 2023 Category: Allergy & Immunology Authors: Maryam Khajvand-Abedini Mahdi Bahmani Nasrin Ziamajidi Alireza Nourian Parisa Habibi Shirin Heidarisasan Roghayeh Abbasalipourkabir Source Type: research