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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity
CONCLUSION: Taken together, the presented data suggest that the PTP1B inhibition strategy and the use of its specific inhibitor MSI-1436 represents a promising option for the improvement of liver tissue integrity and homeostasis in the course of EMS and adds more insights for ongoing clinical trials for human MetS management.PMID:37808009 | PMC:PMC10560121 | DOI:10.1155/2023/3803056 (Source: International Journal of Inflammation)
Source: International Journal of Inflammation - October 9, 2023 Category: Allergy & Immunology Authors: Lynda Bourebaba Anna Serwotka-Suszczak Nabila Bourebaba Magdalena Zyzak Krzysztof Marycz Source Type: research