VET: Vasculature Extraction Transformer for Single-Scan Optical Coherence Tomography Angiography
This study recruited 15 healthy participants. The OCT scans were performed in five various skin sites, i.e., palm, arm, face, neck, and lip. Our results show that in comparison to OCTA images obtained by the speckle variance OCTA (peak-signal-to-noise ratio (PSNR): 16.13) and eigen-decomposition OCTA (PSNR: 17.08) using four repeated OCT scans, OCTA images extracted by the proposed pipeline exhibit a better PSNR (18.03) performance while reducing the data acquisition time by 75%. Visual comparisons show that the proposed pipeline outperformed traditional OCTA algorithms, particularly in the imaging of lip and face areas, w...
Source: IEEE Transactions on Biomedical Engineering - November 6, 2023 Category: Biomedical Engineering Source Type: research

Sensing and Controlling Strategy for Upper Extremity Prosthetics Based on Piezoelectric Micromachined Ultrasound Transducer
Surface electromyography (sEMG) is currently the primary method for user control of prosthetic manipulation. Its inherent limitations of low signal-to-noise ratio, limited specificity and susceptibility to noise, however, hinder successful implementation. Ultrasound provides a possible alternative, but current systems with medical probes are expense, bulky and non-wearable. This work proposes an innovative prosthetic control strategy based on a piezoelectric micromachined ultrasound transducer (PMUT) hardware system. Two PMUT-based probes were developed, comprising a 23×26 PMUT array and encapsulated in Ecoflex material. ...
Source: IEEE Transactions on Biomedical Engineering - November 3, 2023 Category: Biomedical Engineering Source Type: research

A Novel Articulating Chip-on-Tip Endoscope for Dynamic Middle Ear Surgical Visualization
Conclusion: The ACoT Endo's dynamic viewing angle and Chip–on–Tip camera enable unparalleled surgical visualization within the middle ear using a single endoscope, offering potential benefits in Otolaryngology procedures. Significance: By reducing the need for invasive mastoidectomies and providing better visualization tools, the ACoT Endo has significant potential to improve outcomes and safety in pediatric middle ear surgeries. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - November 1, 2023 Category: Biomedical Engineering Source Type: research

Multimodal Vigilance Estimation With Modality-Pairwise Contrastive Loss
Nowadays, how to estimate vigilance with higher accuracy has become a hot field of research direction. Although the increasing available modalities opens the door for amazing new possibilities to achieve good performance, the uncertain cross-modal interaction still poses a real challenge to the multimodal fusion. In this paper, a cross-modality alignment method has been proposed based on the contrastive learning for extracting shared but not the same information among modalities. The contrastive learning is adopted to minimize the intermodal differences by maximizing the similarity of semantic representation of modalities....
Source: IEEE Transactions on Biomedical Engineering - October 31, 2023 Category: Biomedical Engineering Source Type: research

Limiting Temperature Rise in Cochlear Implantation Bone Drilling: A Novel Approach
Conclusion: This method provides a new strategy for accurate and effective control of borehole heat generation. Significance: These achievements provide new ideas and directions for research in cochlear implantation surgery and related fields, and are expected to have extensive application in medical practice. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - October 24, 2023 Category: Biomedical Engineering Source Type: research

Computing Speed-of-Sound From Ultrasound: User-Agnostic Recovery and a New Benchmark
Conclusion: The consideration of the phase of the IQ-signals presents a promising appeal to traversing the transfer learning problem, advancing the goal of real-time speed-of-sound imaging. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - October 24, 2023 Category: Biomedical Engineering Source Type: research

Reliable Prostate Cancer Risk Mapping From MRI Using Targeted and Systematic Core Needle Biopsy Histopathology
Conclusion: The sparseness of prostate biopsy data makes the validation of a whole gland risk mapping a non-trivial task. Previous studies i) focused on targeted-biopsy locations although biopsy-specimens drawn from systematically scattered locations across the prostate constitute a more representative sample to non-biopsied regions, and ii) estimated prediction-power across predicted instances (e.g., biopsy specimens) with no patient distinction, which may lead to unreliable estimation of model fitness to the individual patient due to variation between patients in instance count, imaging characteristics, and pathologies. ...
Source: IEEE Transactions on Biomedical Engineering - October 24, 2023 Category: Biomedical Engineering Source Type: research

Transcutaneous Magnet Localizer for a Self-Contained Myokinetic Prosthetic Hand
Objective: The search for a physiologically appropriate interface for the control of dexterous hand prostheses is an ongoing challenge in bioengineering. In this context, we proposed an interface, named myokinetic control interface, based on the localization of magnets implanted in the residual limb muscles, to monitor their contractions and send appropriate commands to the artificial hand. As part of such concept, this interface requires a transcutaneous magnet localizer that can be integrated in a self-contained limb prosthesis, a feature yet to be realized within the current state of the art. Methods: In an attempt to c...
Source: IEEE Transactions on Biomedical Engineering - October 19, 2023 Category: Biomedical Engineering Source Type: research

Long-Term Dependency for 3D Reconstruction of Freehand Ultrasound Without External Tracker
Conclusion: The proposed algorithm uses hyperparameter tuning to effectively utilise long-term dependency. The proposed dependency factors are of practical significance in collecting diverse training data, regulating scanning protocols and developing efficient networks. Significance: The proposed new methodology with publicly available volunteer data and code11[Online]. Available: https://github.com/ucl-candi/freehand for parametersing the long-term dependency, experimentally shown to be valid sources of performance improvement, which could potentially lead to better model development and practical optimisation of the reco...
Source: IEEE Transactions on Biomedical Engineering - October 19, 2023 Category: Biomedical Engineering Source Type: research

A Generalized Full-to-Partial Registration Framework of 3D Point Sets for Computer-Aided Orthopedic Surgery
Conclusion and significance: Hence, our proposed method is capable of achieving precise bone alignments for computer-aided orthopedic surgery. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - October 19, 2023 Category: Biomedical Engineering Source Type: research

A Soft Robotic Actuator System for In Vivo Modeling of Normal Pressure Hydrocephalus
Conclusion: The introduced soft robotic actuator system is capable of ICP waveform manipulation. Significance: Continuous amplification of the intracranial pulse pressure could enable in vivo modeling of normal pressure hydrocephalus and shunt system testing under pathophysiological conditions to improve therapy for hydrocephalus. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - October 17, 2023 Category: Biomedical Engineering Source Type: research

Evaluation of Robustness of S-Transform Based Phase Velocity Estimation in Viscoelastic Phantoms and Renal Transplants
Ultrasound shear wave elastography (SWE) methods are being used to differentiate healthy versus diseased tissue on the basis of their viscoelastic mechanical properties. Tissue viscoelasticity is often studied by analyzing shear wave phase velocity dispersion curves, which is the variation of phase velocity with frequency or wavelength. Recently, a unique approach using a generalized Stockwell transformation (GST-SFK) was proposed for the calculation of dispersion curves in viscoelastic media over expanded frequency band. In this work, the method's robustness was evaluated on data from five custom-made viscoelastic tissue-...
Source: IEEE Transactions on Biomedical Engineering - October 12, 2023 Category: Biomedical Engineering Source Type: research

InterlACE Sound Coding for Unilateral and Bilateral Cochlear Implants
Conclusion: InterlACE processing positively affects speech intelligibility, increases available unilateral and bilateral signal content, and may potentially counteract signal interactions at the electrode-neuron interface. Significance: This work shows how cochlear implant channel selection can be modified and extended bilaterally. The clinical impact of the modifications needs to be explored with a larger sample size. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - October 5, 2023 Category: Biomedical Engineering Source Type: research

Proof of Concept of an Affordable, Compact and Transcranial Submillimeter Accurate Ultrasound-Based Tracking System
In neurosurgery, a current challenge is to provide localized therapy in deep and difficult-to-access brain areas with millimeter accuracy. In this prospect, new surgical devices such as microrobots are being developed, which require controlled inbrain navigation to ensure the safety and efficiency of the intervention. In this context, the device tracking technology has to answer a three-sided challenge: invasiveness, performance, and facility of use. Although ultrasound seems appropriate for transcranial tracking, the skull remains an obstacle because of its significant acoustic perturbations. A compact and affordable ultr...
Source: IEEE Transactions on Biomedical Engineering - October 5, 2023 Category: Biomedical Engineering Source Type: research

Gaussian Processes for Hearing Threshold Estimation Using Auditory Brainstem Responses
The Auditory Brainstem Response (ABR) plays an important role in diagnosing and managing hearing loss, but can be challenging and time-consuming to measure. Test times are especially long when multiple ABR measurements are needed, e.g., when estimating hearing threshold at a range of frequencies. While many detection methods have been developed to reduce ABR test times, the majority were designed to detect the ABR at a single stimulus level and do not consider correlations in ABR waveforms across levels. These correlations hold valuable information, and can be exploited for more efficient hearing threshold estimation. This...
Source: IEEE Transactions on Biomedical Engineering - September 28, 2023 Category: Biomedical Engineering Source Type: research