Accurate Real-Time Joint Torque Estimation for Dynamic Prediction of Human Locomotion
Inverse dynamics is a common tool for determining human joint torques during walking. The traditional approaches rely on ground reaction force and kinematics measurements prior to analysis. A novel real-time hybrid method is proposed in this work by integrating a neural network and dynamic model that only requires kinematic data. An end-to-end neural network for direct joint torque estimation is also developed based on kinematic data. The neural networks are trained on a variety of walking conditions, including starting and stopping, sudden speed changes, and asymmetrical walking. The hybrid model is first tested in a deta...
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

Miniaturized Stacked Transducer for Intravascular Sonothrombolysis With Internal-Illumination Photoacoustic Imaging Guidance and Clot Characterization
Thromboembolism in blood vessels can lead to stroke or heart attack and even sudden death unless brought under control. Sonothrombolysis enhanced by ultrasound contrast agents has shown promising outcome on effective treatment of thromboembolism. Intravascular sonothrombolysis was also reported recently with a potential for effective and safe treatment of deep thrombosis. Despite the promising treatment results, the treatment efficiency for clinical application may not be optimized due to the lack of imaging guidance and clot characterization during the thrombolysis procedure. In this paper, a miniaturized transducer was d...
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

Nervous-System-Wise Functional Estimation of Directed Brain–Heart Interplay Through Microstate Occurrences
Conclusion: This study corroborates the literature on the BHI phenomenon under these experimental conditions and the new perspective provides novel insights from an organ–level viewpoint. Significance: A system–wise perspective of the BHI phenomenon may provide new insights into physiological and pathological processe- that may not be completely understood at a lower level/scale of analysis. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

NIR-IIb Fluorescence Molecular Tomography of Glioblastomas Based on Heterogeneous Mouse Models and Adaptive Projection Match Pursuit Method
Conclusion: The results demonstrated that NIR-IIb has better reconstruction performance for positioning accuracy and shape recovery. Significance: The inspiring results in this study demonstrate the effectiveness and advantages of NIR-IIb FMT in precise tumor positioning. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

A Unified User-Generic Framework for Myoelectric Pattern Recognition: Mix-Up and Adversarial Training for Domain Generalization and Adaptation
Conclusion: The proposed method provides an effective and promising way of establishing cross-user myoelectric pattern recognition control systems. Significance: Our work helps to promote development of user-generic myoelectric interfaces, with wide applications in motor control and health. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

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Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

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Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

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Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

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Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

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Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

Modeling Complex EEG Data Distribution on the Riemannian Manifold Toward Outlier Detection and Multimodal Classification
Conclusion: odenRiSC/mcRiSC are anticipated to contribute to making real-life BCIs outside labs and neuroergonomics applications more robust. Significance: RiSC can work as a robust EEG outlier detector and multimodal classifier. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 14, 2023 Category: Biomedical Engineering Source Type: research

Mid-Activity and At-Home Wearable Bioimpedance Elucidates an Interpretable Digital Biomarker of Muscle Fatigue
Objective: Muscle health and decreased muscle performance (fatigue) quantification has proven to be an invaluable tool for both athletic performance assessment and injury prevention. However, existing methods estimating muscle fatigue are infeasible for everyday use. Wearable technologies are feasible for everyday use and can enable discovery of digital biomarkers of muscle fatigue. Unfortunately, the current state-of-the-art wearable systems for muscle fatigue tracking suffer from either low specificity or poor usability. Methods: We propose using dual-frequency bioimpedance analysis (DFBIA) to non-invasively assess intra...
Source: IEEE Transactions on Biomedical Engineering - July 5, 2023 Category: Biomedical Engineering Source Type: research

Improved Configurations for 3D Acoustoelectric Tomography With a Minimal Number of Electrodes
Conclusion: We show that the coupling of AAE and EIT leads to a suppressed signal and the magnitude of the reduction is a function of geometry of the medium, contrast and electrode locations. Significance: This model can aid in the reconstruction of AET images involving a minimum number of electrodes to determine the optimal electrode placement. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 5, 2023 Category: Biomedical Engineering Source Type: research

Intravascular Optical Coherence Tomography Utilizing a Miniature Piezoelectric-Driven Probe
In this study, we developed a miniature optical scanning probe with an integrated piezoelectric-driven fiber optic slip ring (FOSR) to facilitate smooth navigation and precise imaging within tortuous vessels. The FOSR features a coil spring-wrapped optical lens serving as a rotor, enabling efficient 360° optical scanning. The structurally-and-functionally-integrated design significantly streamlines the probe (with a diameter of 0.85 mm and a length of 7 mm) while maintaining an excellent rotational speed of 10,000 rpm. High-precision 3D printing technology ensures accurate optical alignment of the fiber and lens inside th...
Source: IEEE Transactions on Biomedical Engineering - June 28, 2023 Category: Biomedical Engineering Source Type: research

Design, Simulations and Tests of a Novel Force and Moments Sensor for Instrumented Knee Implants
Conclusion: This work shows that relevant mechanical components acting on a tibial tray of a knee implant can be measured in an easy to assemble, leak-proof and mechanically robust design while offering relevant data usable by clinicians during the surgical or rehabilitation procedures. Significance: This work contributes to increase the technological readiness of smart orthopaedic implants. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - June 26, 2023 Category: Biomedical Engineering Source Type: research