Interpersonal Psychotherapy: A Scoping Review and Historical Perspective (1974–2017)
Conclusion
Sparked by clinical innovations and scientific advances, IPT has evolved as an effective treatment of psychiatric disorders across the lifespan for diverse patients, including underserved clinical populations. Future research to elucidate mechanisms of change, improve access, and adapt to changing frameworks of psychopathology and treatment planning is needed. IPT addresses the universal centrality of relationships to mental health, which is as relevant today as it was over 40 years ago. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - May 1, 2019 Category: Psychiatry Tags: REVIEWS Source Type: research
The Amygdala in Schizophrenia and Bipolar Disorder: A Synthesis of Structural MRI, Diffusion Tensor Imaging, and Resting-State Functional Connectivity Findings
Frequently implicated in psychotic spectrum disorders, the amygdala serves as an important hub for elucidating the convergent and divergent neural substrates in schizophrenia and bipolar disorder, the two most studied groups of psychotic spectrum conditions. A systematic search of electronic databases through December 2017 was conducted to identify neuroimaging studies of the amygdala in schizophrenia and bipolar disorder, focusing on structural MRI, diffusion tensor imaging (DTI), and resting-state functional connectivity studies, with an emphasis on cross-diagnostic studies. Ninety-four independent studies were selected ...
Source: Harvard Review of Psychiatry - May 1, 2019 Category: Psychiatry Tags: REVIEWS Source Type: research
Encountering Patient Suicide During Psychiatric Training: An Integrative, Systematic Review
Conclusion
The frequent posttraumatic symptoms and the negative professional consequences following patient suicide are worrying phenomena that highlight the need to improve suicide prevention and postvention programs during psychiatric training. Identifying trainees with personal vulnerability factors should be a major concern during the postvention process. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - May 1, 2019 Category: Psychiatry Tags: REVIEWS Source Type: research
The Emerging Empirical Science of Wisdom: Definition, Measurement, Neurobiology, Longevity, and Interventions
This article seeks to provide an overview of the empirical literature on wisdom in terms of its definitions and measurements, possible neurobiological basis, and evolutionary value, as well as changes with aging and potential clinical interventions to enhance components of wisdom. Wisdom may be defined as a complex human trait with several specific components: social decision making, emotion regulation, prosocial behaviors, self-reflection, acceptance of uncertainty, decisiveness, and spirituality. These components appear to be localized primarily to the prefrontal cortex and limbic striatum. Emerging research suggests tha...
Source: Harvard Review of Psychiatry - May 1, 2019 Category: Psychiatry Tags: REVIEWS Source Type: research
The Medico-Legal, Ethical, and Clinical Challenges of Psychiatric Advance Directives
No abstract available (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - March 1, 2019 Category: Psychiatry Tags: Clinical Challenge Source Type: research
Selective Serotonin Reuptake Inhibitors and Fertility: Considerations for Couples Trying to Conceive
Conclusions
There is insufficient evidence at present to propose that SSRIs reduce fertility or influence infertility-treatment outcomes. SSRIs may have an adverse impact on sperm quality, but further research is warranted. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - March 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
Omega-3 Polyunsaturated Fatty Acid Deficiency and Progressive Neuropathology in Psychiatric Disorders: A Review of Translational Evidence and Candidate Mechanisms
Meta-analytic evidence indicates that mood and psychotic disorders are associated with both omega-3 polyunsaturated fatty acid (omega-3 PUFA) deficits and progressive regional gray and white matter pathology. Although the association between omega-3 PUFA insufficiency and progressive neuropathological processes remains speculative, evidence from translational research suggests that omega-3 PUFA insufficiency may represent a plausible and modifiable risk factor not only for enduring neurodevelopmental abnormalities in brain structure and function, but also for increased vulnerability to neurodegenerative processes. Recent e...
Source: Harvard Review of Psychiatry - March 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
Posttraumatic Stress Disorder in the Primary Care Setting: Summary of Recommended Care
Conclusion
Primary care providers can diagnose and offer initial management of PTSD. Future research should delineate therapies helpful for complex PTSD, including group therapies, those increasing self-compassion, and other optimally effective collaborative care interventions. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - March 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
Collaborative Deprescribing in Borderline Personality Disorder: A Narrative Review
Learning objectives
After participating in this activity, learners should be better able to:
• Assess medication management in patients with borderline personality disorder (BPD)
• Evaluate the role of deprescribing as an active intervention in patients with BPD treated with polypharmacy
Psychopharmacology in borderline personality disorder (BPD) is complicated by comorbid disorders, substance use, sensitivity to side effects, risk of self-harm through medication misuse, and intense but transient symptoms. Patients’ relationships with medications may range from tenuous to highly enmeshed, and may profoundly infl...
Source: Harvard Review of Psychiatry - March 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
Acknowledgments
No abstract available (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Acknowledgments Source Type: research
“Gambling with God”: A Self-Inflicted Gunshot Wound with Religious Motivation in the Context of a Mixed-Mood Episode
No abstract available (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Clinical Challenge Source Type: research
Integrating Genomics into Psychiatric Practice: Ethical and Legal Challenges for Clinicians
Psychiatric genomics is a rapidly growing field that holds much promise for improving risk prediction, prevention, diagnosis, treatment selection, and understanding of the pathogenesis of patients’ symptoms. The field of psychiatry (i.e., professional organizations, mental health clinicians, educational institutions), however, needs to address numerous challenges to promote the responsible translation of genomic technologies and knowledge into psychiatric practice. The goal of this article is to review how clinicians currently encounter and use genomics in the clinic, to summarize the existing literature on how clinician...
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Perspectives Source Type: research
The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An Update on Unipolar Nonpsychotic Depression
Background
The Psychopharmacology Algorithm Project at the Harvard South Shore Program presents evidence-based recommendations considering efficacy, tolerability, safety, and cost. Two previous algorithms for unipolar nonpsychotic depression were published in 1993 and 1998. New studies over the last 20 years suggest that another update is needed.
Methods
The references reviewed for the previous algorithms were reevaluated, and a new literature search was conducted to identify studies that would either support or alter the previous recommendations. Other guidelines and algorithms were consulted. We considered exception...
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
The Prevalence of Negative Symptoms Across the Stages of the Psychosis Continuum
Conclusions
Certain psychological, environmental, and treatment-related factors may influence the cumulative impact of negative symptoms, presenting the possibility for early intervention to improve the long-term course. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
Diagnostic Stability in Bipolar Disorder: A Narrative Review
Conclusions
Several factors appear to have a negative impact on the diagnostic stability, but the evidence is insufficient to draw any robust conclusions. Nevertheless, despite variable prospective and retrospective consistencies, the overall diagnostic stability is good. Standardized methods need to be used to obtain more accurate assessments of stability. (Source: Harvard Review of Psychiatry)
Source: Harvard Review of Psychiatry - January 1, 2019 Category: Psychiatry Tags: Reviews Source Type: research
