Microstructural adaptations of the subchondral bone are related to the mechanical axis deviation in end stage varus oa knees
Eur Cell Mater. 2023 Feb 20;45:60-71. doi: 10.22203/eCM.v045a05.ABSTRACTRecent studies highlighted the crucial contribution of subchondral bone to OA development. Yet, only limited data have been reported on the relation between alteration to cartilage morphology, structural properties of the subchondral bone plate (SBP) and underlying subchondral trabecular bone (STB). Furthermore, the relationship between the morphometry of the cartilage and bone in the tibial plateau and the OA-induced changes in the joint's mechanical axis remains unexplored. Therefore, a visualisation and quantification of cartilage and subchondral bo...
Source: European Cells and Materials - February 22, 2023 Category: Cytology Authors: W Colyn F Azari J Bellemans G Harry van Lenthe L Scheys Source Type: research
Mandibular condylar process remodeling in rats with different bite-altering devices
The objective was to compare different dental splint models and materials for inducing abnormal loading on the gross morphology and histological appearance of the mandibular condylar processes of Sprague Dawley rats. Three different types of dental splints (resin molar, aluminum incisor, stainless-steel incisor) were placed unilaterally to induce occlusal perturbation for 4 weeks. At that time, mandibular condylar processes were assessed by gross appearance and histology. Quantitative measurements were also conducted on the hematoxylin and eosin images for condyle shape. The results showed that although the condylar cartil...
Source: European Cells and Materials - February 14, 2023 Category: Cytology Authors: W Li S Trbojevic J B Pineda-Farias X Liu M S Gold A J Almarza Source Type: research
