Application of Multigene Panel Testing in Patients With High Risk for Hereditary Colorectal Cancer: A Descriptive Report Focused on Genotype-Phenotype Correlation
CONCLUSIONS:
A comprehensive multigene panel is expected to identify more genetic mutations than phenotype-based direct sequencing, with special utility for unclear phenotype or genotype-phenotype discordance. See Video Abstract at http://links.lww.com/DCR/B844.
APLICACIÓN DE PRUEBAS DE PANEL MULTIGÉNICO EN PACIENTES CON ALTO RIESGO DE CÁNCER COLORRECTAL HEREDITARIO: INFORME DESCRIPTIVO ENFOCADO EN LA CORRELACIÓN GENOTIPO-FENOTIPO
ANTECEDENTES:
La prueba genética basada únicamente en la característica clínica del cáncer colorrectal hereditario tiene limitaciones en la práctica clínica.
OBJETIVO:...
Source: Diseases of the Colon and Rectum - May 13, 2022 Category: Gastroenterology Tags: Original Contributions: Colorectal Cancer Source Type: research
Advocacy: What Every Colorectal Surgeon Needs to Know to Make a Critical Impact on Health Care Policy
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - May 13, 2022 Category: Gastroenterology Tags: Commentaries and Educational Content: Legislative Updates and Healthcare Economics Source Type: research
Expert Commentary on the Evaluation and Management of Lower GI Bleeding
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - May 13, 2022 Category: Gastroenterology Tags: Commentaries and Educational Content: Resident’s Corner Source Type: research
Evaluation and Management of Lower GI Bleeding
CASE SUMMARY:
A 73-year-old woman, who had received apixaban for therapeutic anticoagulation, presented with hypotension and hematochezia. After resuscitation, diagnostic colonoscopy revealed multiple polyps and old blood within the colonic lumen, but no active bleeding (Fig. 1). Nasogastric lavage and subsequent EGD were unremarkable. During her hospitalization, she was admitted to the intensive care unit with worsening anemia, hypotension, and hematochezia. CT angiogram showed extravasation at the transverse colon (Fig. 1). Formal angiogram was unable to localize the source of bleeding, despite provocation. Given the...
Source: Diseases of the Colon and Rectum - May 13, 2022 Category: Gastroenterology Tags: Commentaries and Educational Content: Resident’s Corner Source Type: research
Genetic Testing in Colorectal Surgery: Routine Profiling of Tumor Genomes is Not Far Off
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - May 13, 2022 Category: Gastroenterology Tags: Commentaries and Educational Content: Editorial Source Type: research
Colon and Rectal Surgery Regional Society Meetings
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Colon and Rectal Surgery Regional Society Meetings Source Type: research
Announcements
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Announcements Source Type: research
Meeting Abstracts from the 2022 Annual Scientific Meeting of the American Society of Colon and Rectal Surgeons
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: ASCRS Meeting Abstracts Source Type: research
May 2022 translations
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Chinese Content Source Type: research
Reply
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
High Recurrence Rate After Nonsurgical Treatment of Chronic Anal Fissure: Can It Be Prevented?
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
Reply
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
Comment on "Perioperative Blood Transfusions Are Associated With Worse Overall Survival But Not Disease-Free Survival After Curative Rectal Cancer Resection: A Propensity Score-Matched Analysis"
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
Reply
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
Comment on “Perioperative Blood Transfusions Are Associated With Worse Overall Survival but Not Disease-Free Survival After Curative Rectal Cancer Resection: A Propensity Score-Matched Analysis”—Confusing Patient Numbers at Risk
No abstract available (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - April 14, 2022 Category: Gastroenterology Tags: Web-Exclusive Content: Letters to the Editor Source Type: research
