Intravenous Thrombolysis is Effective in Mild Stroke Patients with an Admission NIHSS Score of 3 to 5
CONCLUSIONS: Intravenous thrombolysis is safe and effective in patients with baseline NIHSS scores of 3 to 5. In contrast, it did not improve 90-day functional outcomes in patients with NIHSS scores of 0 to 2 and instead increased the risk of sICH.PMID:37909432 | DOI:10.2174/0115672026275063231023110030 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - November 1, 2023 Category: Neurology Authors: Kai Zhang Lin Han Source Type: research
Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders
Curr Neurovasc Res. 2023 Oct 27. doi: 10.2174/1567202620999231027155308. Online ahead of print.NO ABSTRACTPMID:37888824 | DOI:10.2174/1567202620999231027155308 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 27, 2023 Category: Neurology Authors: Kenneth Maiese Source Type: research
Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders
Curr Neurovasc Res. 2023 Oct 27. doi: 10.2174/1567202620999231027155308. Online ahead of print.NO ABSTRACTPMID:37888824 | DOI:10.2174/1567202620999231027155308 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 27, 2023 Category: Neurology Authors: Kenneth Maiese Source Type: research
Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders
Curr Neurovasc Res. 2023 Oct 27. doi: 10.2174/1567202620999231027155308. Online ahead of print.NO ABSTRACTPMID:37888824 | DOI:10.2174/1567202620999231027155308 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 27, 2023 Category: Neurology Authors: Kenneth Maiese Source Type: research
Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders
Curr Neurovasc Res. 2023 Oct 27. doi: 10.2174/1567202620999231027155308. Online ahead of print.NO ABSTRACTPMID:37888824 | DOI:10.2174/1567202620999231027155308 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 27, 2023 Category: Neurology Authors: Kenneth Maiese Source Type: research
Causal Effects of Blood Metabolites and Obstructive Sleep Apnea: A Mendelian Randomization Study
CONCLUSION: MR (mendelian randomization) approach was performed to identify 6 protective factors and 12 risk factors for OSA in the present study. 3-Dehydrocarnitine was the most significant risk factors for OSA. Our study also confirmed several significant metabolic pathways that were involved in the pathogenesis of OSA. Valine, leucine and isoleucine biosynthesis metabolic pathways were the most significant metabolic pathways that were involved in the pathogenesis of OSA.PMID:37877151 | DOI:10.2174/0115672026266627230921052416 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 25, 2023 Category: Neurology Authors: Jinghao Wu Yinghao Yang Yun Chao Wang Wen Kai Yu Shanshan Li Yunyun Mei Ce Zong Zi Han Zhou HangHang Zhu LiuChang He XinYu Li ChangHe Shi Yusheng Li Source Type: research
Causal Effects of Blood Metabolites and Obstructive Sleep Apnea: A Mendelian Randomization Study
CONCLUSION: MR (mendelian randomization) approach was performed to identify 6 protective factors and 12 risk factors for OSA in the present study. 3-Dehydrocarnitine was the most significant risk factors for OSA. Our study also confirmed several significant metabolic pathways that were involved in the pathogenesis of OSA. Valine, leucine and isoleucine biosynthesis metabolic pathways were the most significant metabolic pathways that were involved in the pathogenesis of OSA.PMID:37877151 | DOI:10.2174/0115672026266627230921052416 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 25, 2023 Category: Neurology Authors: Jinghao Wu Yinghao Yang Yun Chao Wang Wen Kai Yu Shanshan Li Yunyun Mei Ce Zong Zi Han Zhou HangHang Zhu LiuChang He XinYu Li ChangHe Shi Yusheng Li Source Type: research
Causal Effects of Blood Metabolites and Obstructive Sleep Apnea: A Mendelian Randomization Study
CONCLUSION: MR (mendelian randomization) approach was performed to identify 6 protective factors and 12 risk factors for OSA in the present study. 3-Dehydrocarnitine was the most significant risk factors for OSA. Our study also confirmed several significant metabolic pathways that were involved in the pathogenesis of OSA. Valine, leucine and isoleucine biosynthesis metabolic pathways were the most significant metabolic pathways that were involved in the pathogenesis of OSA.PMID:37877151 | DOI:10.2174/0115672026266627230921052416 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 25, 2023 Category: Neurology Authors: Jinghao Wu Yinghao Yang Yun Chao Wang Wen Kai Yu Shanshan Li Yunyun Mei Ce Zong Zi Han Zhou HangHang Zhu LiuChang He XinYu Li ChangHe Shi Yusheng Li Source Type: research
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons
CONCLUSION: Smurf2 overexpression facilitated the ubiquitination of FOXO4 to reduce its protein level, thereby suppressing DCDC2 transcription and restricting OGD/R-induced pyroptosis of cortical neurons.PMID:37861000 | DOI:10.2174/0115672026267629230920062917 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 20, 2023 Category: Neurology Authors: Bin Yan Yan Jin Song Mao Yi Zhang Dahong Yang Mingyang Du Yugang Yin Source Type: research
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons
CONCLUSION: Smurf2 overexpression facilitated the ubiquitination of FOXO4 to reduce its protein level, thereby suppressing DCDC2 transcription and restricting OGD/R-induced pyroptosis of cortical neurons.PMID:37861000 | DOI:10.2174/0115672026267629230920062917 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 20, 2023 Category: Neurology Authors: Bin Yan Yan Jin Song Mao Yi Zhang Dahong Yang Mingyang Du Yugang Yin Source Type: research
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons
CONCLUSION: Smurf2 overexpression facilitated the ubiquitination of FOXO4 to reduce its protein level, thereby suppressing DCDC2 transcription and restricting OGD/R-induced pyroptosis of cortical neurons.PMID:37861000 | DOI:10.2174/0115672026267629230920062917 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 20, 2023 Category: Neurology Authors: Bin Yan Yan Jin Song Mao Yi Zhang Dahong Yang Mingyang Du Yugang Yin Source Type: research
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons
CONCLUSION: Smurf2 overexpression facilitated the ubiquitination of FOXO4 to reduce its protein level, thereby suppressing DCDC2 transcription and restricting OGD/R-induced pyroptosis of cortical neurons.PMID:37861000 | DOI:10.2174/0115672026267629230920062917 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 20, 2023 Category: Neurology Authors: Bin Yan Yan Jin Song Mao Yi Zhang Dahong Yang Mingyang Du Yugang Yin Source Type: research
Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders
CONCLUSION: Our findings highlight the potential of targeting the AKT/mTOR/p70S6K pathway in promoting oligodendrocyte differentiation and myelin regeneration in neurological disorders such as SCI.PMID:37817523 | DOI:10.2174/0115672026274954230919070115 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 11, 2023 Category: Neurology Authors: Chen Ge Changwei Li Source Type: research
Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders
CONCLUSION: Our findings highlight the potential of targeting the AKT/mTOR/p70S6K pathway in promoting oligodendrocyte differentiation and myelin regeneration in neurological disorders such as SCI.PMID:37817523 | DOI:10.2174/0115672026274954230919070115 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 11, 2023 Category: Neurology Authors: Chen Ge Changwei Li Source Type: research
Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders
CONCLUSION: Our findings highlight the potential of targeting the AKT/mTOR/p70S6K pathway in promoting oligodendrocyte differentiation and myelin regeneration in neurological disorders such as SCI.PMID:37817523 | DOI:10.2174/0115672026274954230919070115 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - October 11, 2023 Category: Neurology Authors: Chen Ge Changwei Li Source Type: research
