HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Cognitive deficits: Verbal and semantic fluency in people living with HIV and AIDS
CONCLUSION: The study data proves that language deficits are detectable in neurocognitive testing for HIV. The overall hypothesis of the study has been confirmed. The language impairments are primarily qualitative and can be used as a marker for the initial and subsequent therapy assessment.PMID:37312442 | DOI:10.2174/1570162X21666230613124240 (Source: Current HIV Research)
Source: Current HIV Research - June 14, 2023 Category: Infectious Diseases Authors: Ganka Ivanova Rakan Alhrahsheh Kaloyan Kukov Source Type: research
Alkaloids as Potential anti-HIV agents
CONCLUSION: The authors concluded that tubocurarine and reserpine could be further promoted as potential lead molecules for the development of new HIV drugs.PMID:37291776 | DOI:10.2174/1570162X21666230608114130 (Source: Current HIV Research)
Source: Current HIV Research - June 9, 2023 Category: Infectious Diseases Authors: Nidhi Rani Randhir Singh Praveen Kumar Prerna Sharma Rajwinder Kaur Rashmi Arora Thakur Gurjeet Singh Source Type: research
Alkaloids as Potential anti-HIV agents
CONCLUSION: The authors concluded that tubocurarine and reserpine could be further promoted as potential lead molecules for the development of new HIV drugs.PMID:37291776 | DOI:10.2174/1570162X21666230608114130 (Source: Current HIV Research)
Source: Current HIV Research - June 9, 2023 Category: Infectious Diseases Authors: Nidhi Rani Randhir Singh Praveen Kumar Prerna Sharma Rajwinder Kaur Rashmi Arora Thakur Gurjeet Singh Source Type: research
Alkaloids as Potential anti-HIV agents
CONCLUSION: The authors concluded that tubocurarine and reserpine could be further promoted as potential lead molecules for the development of new HIV drugs.PMID:37291776 | DOI:10.2174/1570162X21666230608114130 (Source: Current HIV Research)
Source: Current HIV Research - June 9, 2023 Category: Infectious Diseases Authors: Nidhi Rani Randhir Singh Praveen Kumar Prerna Sharma Rajwinder Kaur Rashmi Arora Thakur Gurjeet Singh Source Type: research
Alkaloids as Potential anti-HIV agents
CONCLUSION: The authors concluded that tubocurarine and reserpine could be further promoted as potential lead molecules for the development of new HIV drugs.PMID:37291776 | DOI:10.2174/1570162X21666230608114130 (Source: Current HIV Research)
Source: Current HIV Research - June 9, 2023 Category: Infectious Diseases Authors: Nidhi Rani Randhir Singh Praveen Kumar Prerna Sharma Rajwinder Kaur Rashmi Arora Thakur Gurjeet Singh Source Type: research
Alkaloids as Potential anti-HIV agents
CONCLUSION: The authors concluded that tubocurarine and reserpine could be further promoted as potential lead molecules for the development of new HIV drugs.PMID:37291776 | DOI:10.2174/1570162X21666230608114130 (Source: Current HIV Research)
Source: Current HIV Research - June 9, 2023 Category: Infectious Diseases Authors: Nidhi Rani Randhir Singh Praveen Kumar Prerna Sharma Rajwinder Kaur Rashmi Arora Thakur Gurjeet Singh Source Type: research
Prevalence of Transmitted Drug Resistance among HIV-1 Patients in the Aegean Region: Results from the Western part of Turkey
CONCLUSION: Transmitted drug resistance rate in the Aegean Region is compatible with national and regional data. Routine surveillance of resistance mutations may guide the safe and correct selection of initial drug combinations for antiretroviral therapy. The identification of HIV-1 subtypes and recombinant forms in Turkey may contribute to international molecular epidemiological data.PMID:37231747 | DOI:10.2174/1570162X21666230525145529 (Source: Current HIV Research)
Source: Current HIV Research - May 26, 2023 Category: Infectious Diseases Authors: Ruchan Sertoz Duygu Tekin Selda Erensoy Servet Biceroglu Figen Kaptan Sukran K öse Hulya Ozkan Banu Cetin Melda T ürken Deniz Gokengin Source Type: research
Prevalence of Transmitted Drug Resistance among HIV-1 Patients in the Aegean Region: Results from the Western part of Turkey
CONCLUSION: Transmitted drug resistance rate in the Aegean Region is compatible with national and regional data. Routine surveillance of resistance mutations may guide the safe and correct selection of initial drug combinations for antiretroviral therapy. The identification of HIV-1 subtypes and recombinant forms in Turkey may contribute to international molecular epidemiological data.PMID:37231747 | DOI:10.2174/1570162X21666230525145529 (Source: Current HIV Research)
Source: Current HIV Research - May 26, 2023 Category: Infectious Diseases Authors: Ruchan Sertoz Duygu Tekin Selda Erensoy Servet Biceroglu Figen Kaptan Sukran K öse Hulya Ozkan Banu Cetin Melda T ürken Deniz Gokengin Source Type: research
Prevalence of Transmitted Drug Resistance among HIV-1 Patients in the Aegean Region: Results from the Western part of Turkey
CONCLUSION: Transmitted drug resistance rate in the Aegean Region is compatible with national and regional data. Routine surveillance of resistance mutations may guide the safe and correct selection of initial drug combinations for antiretroviral therapy. The identification of HIV-1 subtypes and recombinant forms in Turkey may contribute to international molecular epidemiological data.PMID:37231747 | DOI:10.2174/1570162X21666230525145529 (Source: Current HIV Research)
Source: Current HIV Research - May 26, 2023 Category: Infectious Diseases Authors: Ruchan Sertoz Duygu Tekin Selda Erensoy Servet Biceroglu Figen Kaptan Sukran K öse Hulya Ozkan Banu Cetin Melda T ürken Deniz Gokengin Source Type: research
