HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
HIV Preintegration Transcription and Host Antagonism
Curr HIV Res. 2023 Jun 21. doi: 10.2174/1570162X21666230621122637. Online ahead of print.ABSTRACTRetrovirus integration is an obligatory step for the viral life cycle, but large amounts of unintegrated DNA (uDNA) accumulate during retroviral infection. For simple retroviruses, in the absence of integration, viral genomes are epigenetically silenced in host cells. For complex retroviruses such as HIV, preintegration transcription has been found to occur at low levels from a large population of uDNA even in the presence of host epigenetic silencing mechanisms. HIV preintegration transcription has been suggested to be a norma...
Source: Current HIV Research - June 22, 2023 Category: Infectious Diseases Authors: Yuntao Wu Source Type: research
