A novel nucleic acid sensing-related genes signature for predicting immunotherapy efficacy and prognosis of lung adenocarcinoma
CONCLUSION: We found a significant correlation between nucleic acid sensing function and the immune treatment efficiency in LUAD. The NASRS can be used as a robust biomarker for the predicting of prognosis and immunotherapy efficiency and may help in clinical decisions for LUAD patients.PMID:37592781 | DOI:10.2174/1568009623666230817101843 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Xinhao Peng Hong Wu Biqin Zhang Chuan Xu Jinyi Lang Source Type: research
Research progress of neural invasion in pancreatic cancer
This article systematically reviewed the neural invasion of pancreatic cancer through bioinformatics analysis, clinical manifestations and literature reviews.PMID:37592782 | DOI:10.2174/1568009623666230817105221 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Mengying Zhu Feng Luo Bin Xu Jian Xu Source Type: research
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA
CONCLUSION: Our results indicate that miRNA-383-5p functions as an anti-oncogene by inhibiting the VEGFA/Akt/mTOR signaling pathway in glioma cells. These data provide potential therapeutic targets for glioblastoma.PMID:37592783 | DOI:10.2174/1568009623666230817102104 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Yan Liu Zhen Wang Zhi Tang Yao Fu Lei Wang Source Type: research
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer
CONCLUSION: The study indicates that COL10A1 might participate in M2 macrophage polarization in prostate cancer. COL10A1 might be an innovative biomarker to evaluate tumor microenvironment immune cell infiltration and prognosis in prostate cancer.PMID:37592784 | DOI:10.2174/1568009623666230817101809 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Chenyang Wang Jirong Wang Siyu Chen Kunpeng Li Shun Wan Li Yang Source Type: research
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: an in Vivo Study Using Mouse Painting Assay
CONCLUSION: The findings of this study revealed that C. sativum and A. triphylla could protect against cancer development as indicated using the animal model of skin painting assay.PMID:37592785 | DOI:10.2174/1568009623666230817101757 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Omar F Khabour Sawsan Abuhammad Karem H Alzoubi Ahmad S Alkofahi Source Type: research
A Saffron based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats
CONCLUSION: Duk significantly protects rat liver from hepatocarcinogenesis by regulating oxidative damage and restoring serum markers. The chemopreventive effect of Duk might be through induction of apoptosis.PMID:37594101 | DOI:10.2174/1568009623666230818115905 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Meenakshi Gupta Hemlata Nimesh Anwar L Bilgrami Maryam Sarwat Source Type: research
EZH2-regulated PARP 1 Expression is a Likely Mechanism for the Chemoresistance of Gliomas to Temozolomide
CONCLUSION: EZH2 PARP 1 signaling axis is possibly responsible for the chemoresistance of gliomas to TMZ. Simultaneously inhibiting these two genes may improve the outcome of TMZ chemotherapy.PMID:37594167 | DOI:10.2174/1568009623666230818151830 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Qiang Liang Bing Wang Chenran Zhang Chaoli Song Junyu Wang Wei Sun Lei Jiang Jing Lin Source Type: research
A novel nucleic acid sensing-related genes signature for predicting immunotherapy efficacy and prognosis of lung adenocarcinoma
CONCLUSION: We found a significant correlation between nucleic acid sensing function and the immune treatment efficiency in LUAD. The NASRS can be used as a robust biomarker for the predicting of prognosis and immunotherapy efficiency and may help in clinical decisions for LUAD patients.PMID:37592781 | DOI:10.2174/1568009623666230817101843 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Xinhao Peng Hong Wu Biqin Zhang Chuan Xu Jinyi Lang Source Type: research
Research progress of neural invasion in pancreatic cancer
This article systematically reviewed the neural invasion of pancreatic cancer through bioinformatics analysis, clinical manifestations and literature reviews.PMID:37592782 | DOI:10.2174/1568009623666230817105221 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Mengying Zhu Feng Luo Bin Xu Jian Xu Source Type: research
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA
CONCLUSION: Our results indicate that miRNA-383-5p functions as an anti-oncogene by inhibiting the VEGFA/Akt/mTOR signaling pathway in glioma cells. These data provide potential therapeutic targets for glioblastoma.PMID:37592783 | DOI:10.2174/1568009623666230817102104 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Yan Liu Zhen Wang Zhi Tang Yao Fu Lei Wang Source Type: research
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer
CONCLUSION: The study indicates that COL10A1 might participate in M2 macrophage polarization in prostate cancer. COL10A1 might be an innovative biomarker to evaluate tumor microenvironment immune cell infiltration and prognosis in prostate cancer.PMID:37592784 | DOI:10.2174/1568009623666230817101809 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Chenyang Wang Jirong Wang Siyu Chen Kunpeng Li Shun Wan Li Yang Source Type: research
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: an in Vivo Study Using Mouse Painting Assay
CONCLUSION: The findings of this study revealed that C. sativum and A. triphylla could protect against cancer development as indicated using the animal model of skin painting assay.PMID:37592785 | DOI:10.2174/1568009623666230817101757 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Omar F Khabour Sawsan Abuhammad Karem H Alzoubi Ahmad S Alkofahi Source Type: research
A Saffron based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats
CONCLUSION: Duk significantly protects rat liver from hepatocarcinogenesis by regulating oxidative damage and restoring serum markers. The chemopreventive effect of Duk might be through induction of apoptosis.PMID:37594101 | DOI:10.2174/1568009623666230818115905 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Meenakshi Gupta Hemlata Nimesh Anwar L Bilgrami Maryam Sarwat Source Type: research
EZH2-regulated PARP 1 Expression is a Likely Mechanism for the Chemoresistance of Gliomas to Temozolomide
CONCLUSION: EZH2 PARP 1 signaling axis is possibly responsible for the chemoresistance of gliomas to TMZ. Simultaneously inhibiting these two genes may improve the outcome of TMZ chemotherapy.PMID:37594167 | DOI:10.2174/1568009623666230818151830 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Qiang Liang Bing Wang Chenran Zhang Chaoli Song Junyu Wang Wei Sun Lei Jiang Jing Lin Source Type: research
A novel nucleic acid sensing-related genes signature for predicting immunotherapy efficacy and prognosis of lung adenocarcinoma
CONCLUSION: We found a significant correlation between nucleic acid sensing function and the immune treatment efficiency in LUAD. The NASRS can be used as a robust biomarker for the predicting of prognosis and immunotherapy efficiency and may help in clinical decisions for LUAD patients.PMID:37592781 | DOI:10.2174/1568009623666230817101843 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Xinhao Peng Hong Wu Biqin Zhang Chuan Xu Jinyi Lang Source Type: research
