Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239 (Source: Current Cancer Drug Targets)
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
