Intensive Care Unit Organization and Interdisciplinary Care for Critically Ill Patients with Cancer
This article provides an overview of the current state-of-the-art in multidisciplinary care for critically ill patients with cancer. Better integration of multidisciplinary critical care into the continuum of care for patients with cancer offers the prospect of further improvements in the outcomes of patients with cancer. (Source: Critical Care Clinics)
Source: Critical Care Clinics - October 28, 2020 Category: Intensive Care Authors: Alexander Shimabukuro-Vornhagen Source Type: research
Critical Care of Hematopoietic Stem Cell Transplant Patients
Life-threatening complications are frequent after hematopoietic stem cell transplant (HSCT), and optimum critical care is essential to ensuring good outcomes. The immunologic consequences of HSCT result in a markedly different host response to critical illness. Infection is the most common cause of critical illness but noninfectious complications are frequent. Respiratory failure or sepsis are the typical presentations but the sequelae of HSCT can affect nearly any organ system. Pattern recognition can facilitate anticipation and early intervention in post-HSCT critical illness. HSCT critical care is a multidisciplinary en...
Source: Critical Care Clinics - October 26, 2020 Category: Intensive Care Authors: Rachael A. Fornwalt, Emily P. Brigham, R. Scott Stephens Source Type: research
Toxicities Associated with Immunotherapy and Approach to Cardiotoxicity with Novel Cancer Therapies
This article focuses on the clinical features, and grading and management of toxicities associated with ICIs and CAR T-cell therapy. In addition, because cardiotoxicity is one of the most harmful effects of anticancer therapeutics, we describe the risk factors and mechanisms of cardiovascular injury associated with newer agents, screening technologies for at-risk patients, and preventive and treatment strategies. (Source: Critical Care Clinics)
Source: Critical Care Clinics - October 26, 2020 Category: Intensive Care Authors: Cristina Gutierrez, Prabalini Rajendram, Stephen M. Pastores Source Type: research
Palliative, Ethics, and End-of-Life Care Issues in the Cancer Patient
End-of-life care of critically ill adult patients with advanced or incurable cancers is imbued with major ethical challenges. Oncologists, hospitalists, and intensivists can inadvertently subjugate themselves to the perceived powers of autonomous patients. Therapeutic illusion and poor insight by surrogates in physicians ’ ability to offer accurate prognosis, missed opportunities and miscommunication by clinicians, and lack of systematic or protocolized approach represent important barriers to high-quality palliative care. Enhanced collaboration, models that allow clinicians and surrogates to share the burdens of decisio...
Source: Critical Care Clinics - October 26, 2020 Category: Intensive Care Authors: Jamie C. Riches, Louis P. Voigt Source Type: research
Dementia and the Critically Ill Older Adult
Dementia is a terminal illness that leads to progressive cognitive and functional decline. As the elderly population grows, the incidence of dementia in hospitalized older adults increases and is associated with poor short-term and long-term outcomes. Delirium is associated with an accelerated cognitive decline in hospitalized patients with dementia. The first step in the management of dementia is accurate and early diagnosis. Evidence-based management guidelines in the setting of critical illness and dementia are lacking. The cornerstone of management is defining goals of care early in the course of hospitalization and us...
Source: Critical Care Clinics - October 26, 2020 Category: Intensive Care Authors: Mira Ghneim, Jose J. Diaz Source Type: research
