The Term Newborn
The care of late preterm and term newborns delivered in hospital settings in the United States is largely standardized with many routine interventions and screenings that are evidence-based and serve to protect newborn ’s and the public’s health. Refusals of various aspects of routine newborn care are uncommon but can be challenging for clinicians who care for newborns to navigate for many reasons. In this article, we describe the spectrum of refusal. We review suggested approaches that clinicians can take sta rting with increasing their own awareness of what specific components of newborn care are refused and why. (So...
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Michelle Leff, Jaspreet Loyal Source Type: research

The Term Newborn
This review provides an update on neonatal hypoglycemia in the term infant, including discussion of glucose metabolism, definitions of hypoglycemia, identification of infants commonly at risk, and the screening, treatment, and potential neurologic outcomes of postnatal hypoglycemia. Neonatal hypoglycemia is a common metabolic condition that continues to plague clinicians because there is no clear relationship between low glucose concentrations or their duration that determines adverse neurologic outcomes. However, severely low, prolonged, recurrent low glucose concentrations in infants who also have marked symptoms such as...
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Eustratia M. Hubbard, William W. Hay Source Type: research

The Term Newborn
Neonatal encephalopathy due to perinatal hypoxia-ischemia (hypoxic-ischemic encephalopathy [HIE]) occurs at a rate of 1 to 3 per 1000 live births. Therapeutic hypothermia is the standard of care and the only currently available therapy to reduce the risk of death or disability in newborns with moderate to severe HIE. Hypothermia therapy needs to be initiated within 6  hours after birth in order to provide the best chance for neuroprotection. All pediatricians and delivery room attendants should be trained to recognize encephalopathy and understand the eligibility criteria for treatment. The modified Sarnat examination is ...
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Sonia Lomeli Bonifacio, Shandee Hutson Source Type: research

The Term Infant
Reproduction, pregnancy, and lactation are all processes that are mandatory for the survival of our species. Evolution has put an enormous amount of energy into the survival of the newborn; and they are, as a rule, robust little beings. However, the transition of the infant at the time of delivery is one of the most amazing and complex physiologic transitions that humans undergo. How the infant manages that transition is key to their survival. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Anup C. Katheria, Lisa Marie Stellwagen Tags: Preface Source Type: research

Newborn Care is a Team Sport
The birth of a healthy newborn is truly a miracle! Increasingly, well-informed parents are looking for a perfect outcome of a pregnancy and delivery that is much anticipated and planned. This puts an added burden on a team that is often operating with imperfect information and a general lack of evidence-based guidelines. Practitioners struggle with various aspects of delivery: optimal time (gestational age), mode (vaginal, cesarean), site (home, hospital), management of labor (induction, augmentation), and so on. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Lucky Jain Tags: Foreword Source Type: research

Care for the Term Newborn
CLINICS IN PERINATOLOGY (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Authors: Anup C. Katheria, Lisa Marie Stellwagen Source Type: research

Copyright
ELSEVIER (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Source Type: research

Contributors
LUCKY JAIN, MD, MBA (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Source Type: research

Contents
Lucky Jain (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Source Type: research

Forthcoming Issues
Advances in Respiratory Management (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Source Type: research

CME Accreditation Page
(Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 1, 2021 Category: Perinatology & Neonatology Source Type: research

Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome
This article describes the current epidemiology of neonatal sepsis, the pathogenesis of brain injury with sepsis, and the reported long-term neurodevelopment outcomes among survivors. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - May 22, 2021 Category: Perinatology & Neonatology Authors: Elizabeth Sewell, Jessica Roberts, Sagori Mukhopadhyay Source Type: research

Necrotizing Enterocolitis
This article discusses risk factors for NEC, how dysbiosis in preterm infants plays a role in the pathogenesis of NEC, and how probiotic and antibiotic therapy may be used to prevent and/or treat NEC and its sequelae. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - May 22, 2021 Category: Perinatology & Neonatology Authors: Jennifer Duchon, Maria E. Barbian, Patricia W. Denning Source Type: research

Neonatal Herpes Simplex Virus Disease
This article defines neonatal herpes simplex virus (HSV) disease and describes the progress over the past 40  years that has revolutionized the management of HSV disease in neonates to improve their outcomes. These advancements include the introduction of acyclovir in the 1980s, polymerase chain reaction (PCR) for the detection of HSV DNA in the 1990s, and recommendations on managing infants born to mothe rs with active genital lesions. Despite these advancements, however, there remain high morbidity and mortality in affected neonates, with need for continued improvement. Areas of high interest include vaccine development...
Source: Clinics in Perinatology - May 22, 2021 Category: Perinatology & Neonatology Authors: Nicole L. Samies, Scott H. James, David W. Kimberlin Source Type: research

HIV in Neonates and Infants
This article provides insights on the current state of perinatal HIV, recent advances, and future needs. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - May 22, 2021 Category: Perinatology & Neonatology Authors: Andres F. Camacho-Gonzalez, Paul Palumbo Source Type: research