The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
CONCLUSION: Our study adds a new principle to the knowledge of the central processing of a GVS response in healthy subjects. The GVS-safety profile of current up to 2 mA was sufficient to elicit a significant GVS nystagmus response in a head-still position in 63% and after a headshake in 79%. Compared to the GVS head-still condition, a headshake enhanced the GVS-induced nystagmus more than twice.SIGNIFICANCE: The headshake helps to identify GVS-induced nystagmus, which can be weak or absent during the head-still condition.PMID:38432184 | DOI:10.1016/j.clinph.2024.02.018 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Maja Striteska Jan Kremlacek Source Type: research
Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking
CONCLUSION: Our findings show that spontaneous blinking is related to striatal dopamine and has a frequency specific deployment in the STN. This correlation depends on the current movement state such as walking.SIGNIFICANCE: This work indicates that subcortical activity following a motor event as well as the relationship between dopamine and motor events can be dependent on the motor state. Accordingly, disease related changes in brain activity should be assessed during natural movement.PMID:38432185 | DOI:10.1016/j.clinph.2024.02.019 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Liyu Cao Chiara Palmisano Xinyu Chen Ioannis U Isaias Barbara F H ändel Source Type: research
Impacts of education level on Montreal Cognitive Assessment and saccades in community residents from Western China
CONCLUSION: Saccades are less susceptible to the influence of education level when compared to MoCA, making saccade a potentially more suitable cognitive screening tool for rural community populations.SIGNIFICANCE: This study represents a pioneering approach by employing saccade detection within community populations to distinguish cognitive function status.PMID:38432186 | DOI:10.1016/j.clinph.2024.02.017 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Hua Li Anjiao Peng Wanlin Lai Junru Wu Shuming Ji Dan Hu Shujuan Chen Chenxing Zhu Qiulei Hong Mingsha Zhang Lei Chen Source Type: research
Timing matters for accurate identification of the epileptogenic zone
CONCLUSIONS: The model based on a short segment of iEEG recording can achieve similar results as a model based on prolonged recordings. The analyzed segment should, however, be carefully and systematically selected, preferably from NREM sleep.SIGNIFICANCE: Random selection of short iEEG segments may give rise to inaccurate localization of the EZ.PMID:38430856 | DOI:10.1016/j.clinph.2024.01.007 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 2, 2024 Category: Neurology Authors: Bartlomiej Chybowski Petr Klimes Jan Cimbalnik Vojtech Travnicek Petr Nejedly Martin Pail Laure Peter-Derex Jeff Hall Fran çois Dubeau Pavel Jurak Milan Brazdil Birgit Frauscher Source Type: research
Timing matters for accurate identification of the epileptogenic zone
CONCLUSIONS: The model based on a short segment of iEEG recording can achieve similar results as a model based on prolonged recordings. The analyzed segment should, however, be carefully and systematically selected, preferably from NREM sleep.SIGNIFICANCE: Random selection of short iEEG segments may give rise to inaccurate localization of the EZ.PMID:38430856 | DOI:10.1016/j.clinph.2024.01.007 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 2, 2024 Category: Neurology Authors: Bartlomiej Chybowski Petr Klimes Jan Cimbalnik Vojtech Travnicek Petr Nejedly Martin Pail Laure Peter-Derex Jeff Hall Fran çois Dubeau Pavel Jurak Milan Brazdil Birgit Frauscher Source Type: research
StairFit MUNE: A free and open source MatLab program for CMAP scan processing
Clin Neurophysiol. 2024 Feb 18;160:111-112. doi: 10.1016/j.clinph.2024.02.015. Online ahead of print.NO ABSTRACTPMID:38422968 | DOI:10.1016/j.clinph.2024.02.015 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Maoqi Chen Ping Zhou Source Type: research
Signatures of migraine aura in high-density-EEG
CONCLUSIONS: Unequivocal signatures of spreading depolarization were not recorded with EEG on the intact scalp in migraine. The decrease in alpha-power contralateral to predominant visual symptoms is consistent with focal depression of spontaneous brain activity as a consequence of cortical spreading depolarization but is not specific thereof.SIGNIFICANCE: Cortical spreading depolarization is relevant in migraine, other paroxysmal neurological disorders and neurointensive care.PMID:38422969 | DOI:10.1016/j.clinph.2024.01.008 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Franz Riederer Johannes Beiersdorf Clemens Lang Agnes Pirker-Kees Antonia Klein Adrian Scutelnic Kirsten Platho-Elwischger Christoph Baumgartner Jens P Dreier Christoph Schankin Source Type: research
Impact of intracranial subclinical seizures on seizure outcomes after SLAH in patients with mesial temporal lobe epilepsy
CONCLUSION: Patients with MTS exhibited favorable short-term and long-term surgical outcome after SLAH. A higher number of i-SCSs was significantly associated with MTS in patients with MTLE. The number of i-SCSs tended to be higher in patients with Engel Ⅰ-Ⅱ surgical outcomes.SIGNIFICANCE: The association between i-SCSs, MTS, and surgical outcomes in MTLE patients undergoing SLAH has significant implications for understanding the underlying mechanisms and identifying potential therapeutic targets to enhance surgical outcomes.PMID:38422970 | DOI:10.1016/j.clinph.2024.02.013 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Taixin Sun Shasha Wu Xi Liu James X Tao Qun Wang Source Type: research
StairFit MUNE: A free and open source MatLab program for CMAP scan processing
Clin Neurophysiol. 2024 Feb 18;160:111-112. doi: 10.1016/j.clinph.2024.02.015. Online ahead of print.NO ABSTRACTPMID:38422968 | DOI:10.1016/j.clinph.2024.02.015 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Maoqi Chen Ping Zhou Source Type: research
Signatures of migraine aura in high-density-EEG
CONCLUSIONS: Unequivocal signatures of spreading depolarization were not recorded with EEG on the intact scalp in migraine. The decrease in alpha-power contralateral to predominant visual symptoms is consistent with focal depression of spontaneous brain activity as a consequence of cortical spreading depolarization but is not specific thereof.SIGNIFICANCE: Cortical spreading depolarization is relevant in migraine, other paroxysmal neurological disorders and neurointensive care.PMID:38422969 | DOI:10.1016/j.clinph.2024.01.008 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Franz Riederer Johannes Beiersdorf Clemens Lang Agnes Pirker-Kees Antonia Klein Adrian Scutelnic Kirsten Platho-Elwischger Christoph Baumgartner Jens P Dreier Christoph Schankin Source Type: research
Impact of intracranial subclinical seizures on seizure outcomes after SLAH in patients with mesial temporal lobe epilepsy
CONCLUSION: Patients with MTS exhibited favorable short-term and long-term surgical outcome after SLAH. A higher number of i-SCSs was significantly associated with MTS in patients with MTLE. The number of i-SCSs tended to be higher in patients with Engel Ⅰ-Ⅱ surgical outcomes.SIGNIFICANCE: The association between i-SCSs, MTS, and surgical outcomes in MTLE patients undergoing SLAH has significant implications for understanding the underlying mechanisms and identifying potential therapeutic targets to enhance surgical outcomes.PMID:38422970 | DOI:10.1016/j.clinph.2024.02.013 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Taixin Sun Shasha Wu Xi Liu James X Tao Qun Wang Source Type: research
Maternal COVID-19 during third trimester pregnancy does not alter brain-stem auditory evoked potentials in infants
Clin Neurophysiol. 2024 Feb 18;160:108-110. doi: 10.1016/j.clinph.2024.02.014. Online ahead of print.NO ABSTRACTPMID:38412744 | DOI:10.1016/j.clinph.2024.02.014 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 27, 2024 Category: Neurology Authors: Lena Verdaguer Daniela I Santa-Cruz M Angeles Sanchez Rold án Vanessa Thonon Marie Antoinette Frick Kimia Rahnama Ignacio Rubio Agusti Dulce Moncho Source Type: research
Association of brain functional connectivity with neurodevelopmental outcomes in healthy full-term newborns
CONCLUSIONS: Functional connectivity of higher-order processing is already present at term age.SIGNIFICANCE: The FBC might be used to guide interventions for optimizing subsequent neurodevelopment even in low-risk newborns.PMID:38412745 | DOI:10.1016/j.clinph.2024.02.009 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - February 27, 2024 Category: Neurology Authors: Venkata C Chirumamilla Laura Hitchings Sarah B Mulkey Tayyba Anwar Robin Baker G Larry Maxwell Josepheen De Asis-Cruz Kushal Kapse Catherine Limperopoulos Adre du Plessis R B Govindan Source Type: research
The blink reflex and its modulation - Part 2: Pathophysiology and clinical utility
Clin Neurophysiol. 2024 Feb 9;160:75-94. doi: 10.1016/j.clinph.2024.02.006. Online ahead of print.ABSTRACTThe blink reflex (BR) is integrated at the brainstem; however, it is modulated by inputs from various structures such as the striatum, globus pallidus, substantia nigra, and nucleus raphe magnus but also from afferent input from the peripheral nervous system. Therefore, it provides information about the pathophysiology of numerous peripheral and central nervous system disorders. The BR is a valuable tool for studying the integrity of the trigemino-facial system, the relevant brainstem nuclei, and circuits. At the same ...
Source: Clinical Neurophysiology - February 27, 2024 Category: Neurology Authors: Aysegul Gunduz Josep Valls-Sol é Tereza Serranov á Gianluca Coppola Markus Kofler Satu K J ääskeläinen Source Type: research
Vagus nerve stimulation and heart rate variability: A scoping review of a somatic oscillatory signal
Clin Neurophysiol. 2024 Feb 16;160:95-107. doi: 10.1016/j.clinph.2024.02.011. Online ahead of print.ABSTRACTThe goal of this review is to synthesize the literature on vagus nerve stimulator (VNS)-related changes in heart rate variability (HRV) in patients with drug-resistant epilepsy (DRE) and assess the role of these changes in seizure relief. A scoping literature review was performed with the following inclusion criteria: primary articles written in English, involved implantable VNS in humans, and had HRV as a primary outcome. Twenty-nine studies were retrieved, however with considerable heterogeneity in study methods. T...
Source: Clinical Neurophysiology - February 27, 2024 Category: Neurology Authors: Caitlin R Wessel Cemal Karakas Zulfi Haneef Ian Mutchnick Source Type: research
