Age- and sex-related oculomotor manifestation of dopamine deficiency in Segawa disease
CONCLUSIONS: The findings can be explained by a dysfunction of the BG-direct pathway impinging on superior colliculus (SC) due to dopamine deficiency. The disturbed inhibitory control of saccades may be explained by increased SC responsivity to visual stimuli.SIGNIFICANCE: Oculomotor abnormalities in SD can be explained by dysfunction of the BG inhibitory pathways reaching SC, with a delayed maturation in male SD patients, consistent with previous pathological/physiological studies.PMID:38064930 | DOI:10.1016/j.clinph.2023.11.010 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Yasuo Terao Hideki Fukuda Okihide Hikosaka Akihiro Yugeta Shun-Ichi Matsuda Francesco Fisicaro Yoshikazu Ugawa Kyoko Hoshino Yoshiko Nomura Source Type: research

Aberrant hyperfocusing in schizophrenia indicated by elevated theta phase-gamma amplitude coupling
CONCLUSIONS: Aberrant hyperfocusing, as reflected by elevated TGC in attention-related brain regions, was related to behavioral performance on the TMT-A/B in schizophrenia patients.SIGNIFICANCE: This study suggests that TGC is a electrophysiological marker for aberrant hyperfocusing of attentional processes that may result in cognitive impairments in schizophrenia patients.PMID:38064931 | DOI:10.1016/j.clinph.2023.11.012 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Su-Jin An Sunah Choi Jun Seo Hwang Sunghyun Park Moonyoung Jang Minah Kim Jun Soo Kwon Source Type: research

Sensory event-related potential morphology predicts age in premature infants
CONCLUSIONS: Sensory-evoked potentials are predictive of age in premature infants and brain age deviations are related to biologically and clinically meaningful individual differences in nervous system maturation.SIGNIFICANCE: This model could be used to detect abnormal development of infants' response to sensory stimuli in their environment and may be predictive of neurodevelopmental outcome.PMID:38064929 | DOI:10.1016/j.clinph.2023.11.007 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Coen S Zandvoort Marianne van der Vaart Shellie Robinson Fatima Usman Gabriela Schmidt Mellado Ria Evans Fry Alan Worley Eleri Adams Rebeccah Slater Luke Baxter Maarten de Vos Caroline Hartley Source Type: research

Age- and sex-related oculomotor manifestation of dopamine deficiency in Segawa disease
CONCLUSIONS: The findings can be explained by a dysfunction of the BG-direct pathway impinging on superior colliculus (SC) due to dopamine deficiency. The disturbed inhibitory control of saccades may be explained by increased SC responsivity to visual stimuli.SIGNIFICANCE: Oculomotor abnormalities in SD can be explained by dysfunction of the BG inhibitory pathways reaching SC, with a delayed maturation in male SD patients, consistent with previous pathological/physiological studies.PMID:38064930 | DOI:10.1016/j.clinph.2023.11.010 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Yasuo Terao Hideki Fukuda Okihide Hikosaka Akihiro Yugeta Shun-Ichi Matsuda Francesco Fisicaro Yoshikazu Ugawa Kyoko Hoshino Yoshiko Nomura Source Type: research

Aberrant hyperfocusing in schizophrenia indicated by elevated theta phase-gamma amplitude coupling
CONCLUSIONS: Aberrant hyperfocusing, as reflected by elevated TGC in attention-related brain regions, was related to behavioral performance on the TMT-A/B in schizophrenia patients.SIGNIFICANCE: This study suggests that TGC is a electrophysiological marker for aberrant hyperfocusing of attentional processes that may result in cognitive impairments in schizophrenia patients.PMID:38064931 | DOI:10.1016/j.clinph.2023.11.012 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Su-Jin An Sunah Choi Jun Seo Hwang Sunghyun Park Moonyoung Jang Minah Kim Jun Soo Kwon Source Type: research

Sensory event-related potential morphology predicts age in premature infants
CONCLUSIONS: Sensory-evoked potentials are predictive of age in premature infants and brain age deviations are related to biologically and clinically meaningful individual differences in nervous system maturation.SIGNIFICANCE: This model could be used to detect abnormal development of infants' response to sensory stimuli in their environment and may be predictive of neurodevelopmental outcome.PMID:38064929 | DOI:10.1016/j.clinph.2023.11.007 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Coen S Zandvoort Marianne van der Vaart Shellie Robinson Fatima Usman Gabriela Schmidt Mellado Ria Evans Fry Alan Worley Eleri Adams Rebeccah Slater Luke Baxter Maarten de Vos Caroline Hartley Source Type: research

Age- and sex-related oculomotor manifestation of dopamine deficiency in Segawa disease
CONCLUSIONS: The findings can be explained by a dysfunction of the BG-direct pathway impinging on superior colliculus (SC) due to dopamine deficiency. The disturbed inhibitory control of saccades may be explained by increased SC responsivity to visual stimuli.SIGNIFICANCE: Oculomotor abnormalities in SD can be explained by dysfunction of the BG inhibitory pathways reaching SC, with a delayed maturation in male SD patients, consistent with previous pathological/physiological studies.PMID:38064930 | DOI:10.1016/j.clinph.2023.11.010 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Yasuo Terao Hideki Fukuda Okihide Hikosaka Akihiro Yugeta Shun-Ichi Matsuda Francesco Fisicaro Yoshikazu Ugawa Kyoko Hoshino Yoshiko Nomura Source Type: research

Aberrant hyperfocusing in schizophrenia indicated by elevated theta phase-gamma amplitude coupling
CONCLUSIONS: Aberrant hyperfocusing, as reflected by elevated TGC in attention-related brain regions, was related to behavioral performance on the TMT-A/B in schizophrenia patients.SIGNIFICANCE: This study suggests that TGC is a electrophysiological marker for aberrant hyperfocusing of attentional processes that may result in cognitive impairments in schizophrenia patients.PMID:38064931 | DOI:10.1016/j.clinph.2023.11.012 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 8, 2023 Category: Neurology Authors: Su-Jin An Sunah Choi Jun Seo Hwang Sunghyun Park Moonyoung Jang Minah Kim Jun Soo Kwon Source Type: research

Transcranial direct current stimulation of the right temporoparietal junction facilitates hippocampal spatial learning in Alzheimer's disease and mild cognitive impairment
CONCLUSIONS: These results suggest that tDCS can facilitate spatial memory consolidation via stimulating the parietal-hippocampal navigation network in AD and MCI patients.SIGNIFICANCE: Our findings suggest that tDCS of the temporoparietal junction may restore spatial navigation and memory deficits in patients with AD and MCI.PMID:38056370 | DOI:10.1016/j.clinph.2023.11.003 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 6, 2023 Category: Neurology Authors: S Philippen A Hanert R Sch önfeld O Granert R Yilmaz U Jensen-Kondering M Splittgerber V Moliadze M Siniatchkin D Berg T Bartsch Source Type: research

Transcranial direct current stimulation of the right temporoparietal junction facilitates hippocampal spatial learning in Alzheimer's disease and mild cognitive impairment
CONCLUSIONS: These results suggest that tDCS can facilitate spatial memory consolidation via stimulating the parietal-hippocampal navigation network in AD and MCI patients.SIGNIFICANCE: Our findings suggest that tDCS of the temporoparietal junction may restore spatial navigation and memory deficits in patients with AD and MCI.PMID:38056370 | DOI:10.1016/j.clinph.2023.11.003 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 6, 2023 Category: Neurology Authors: S Philippen A Hanert R Sch önfeld O Granert R Yilmaz U Jensen-Kondering M Splittgerber V Moliadze M Siniatchkin D Berg T Bartsch Source Type: research

Non-invasive brain stimulation for palatopharyngeal myoclonus associated with hypertrophic olivary nucleus degeneration
Clin Neurophysiol. 2023 Nov 22;157:46-47. doi: 10.1016/j.clinph.2023.11.009. Online ahead of print.NO ABSTRACTPMID:38052148 | DOI:10.1016/j.clinph.2023.11.009 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 5, 2023 Category: Neurology Authors: Soohoan Lee Hae-Yeon Park Gyoung-Hyun Park Youngkook Kim Geun-Young Park Sun Im Source Type: research

Non-invasive brain stimulation for palatopharyngeal myoclonus associated with hypertrophic olivary nucleus degeneration
Clin Neurophysiol. 2023 Nov 22;157:46-47. doi: 10.1016/j.clinph.2023.11.009. Online ahead of print.NO ABSTRACTPMID:38052148 | DOI:10.1016/j.clinph.2023.11.009 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 5, 2023 Category: Neurology Authors: Soohoan Lee Hae-Yeon Park Gyoung-Hyun Park Youngkook Kim Geun-Young Park Sun Im Source Type: research

Hippocampal barques and their manifestation as 14 & amp;6 Hz positive spikes during sleep
CONCLUSIONS: Hippocampal barques are predominant in NREM II and SWS, and tend to increase their presence during SWS. Their scalp manifestation as 14&6/sec positive spikes is confounded by wakefulness, REM and NREM I stages, and "masked" by the co-occurrence of NREM II and SWS slow waves, and overlapping reactive micro-arousal elements.SIGNIFICANCE: Our study highlighted the overnight profile of hippocampal barques, in relation to the respective profile of their scalp manifestation, the 14&6/sec positive spikes variant.PMID:38042011 | DOI:10.1016/j.clinph.2023.11.008 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 2, 2023 Category: Neurology Authors: Vasileios Kokkinos Helweh Hussein Danai Georgia Sakelliadou R Mark Richardson Anto Ι Bagić Alexandra Urban Source Type: research

Involvement of interhemispheric inhibition in ballistic movement-induced transient suppression of voluntary movement
Clin Neurophysiol. 2023 Nov 20;157:44-45. doi: 10.1016/j.clinph.2023.11.006. Online ahead of print.NO ABSTRACTPMID:38042012 | DOI:10.1016/j.clinph.2023.11.006 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 2, 2023 Category: Neurology Authors: Kai-Hsiang Stanley Chen Yih-Chih Jacinta Kuo Yan-Siou Dong Robert Chen Source Type: research

Hippocampal barques and their manifestation as 14 & amp;6 Hz positive spikes during sleep
CONCLUSIONS: Hippocampal barques are predominant in NREM II and SWS, and tend to increase their presence during SWS. Their scalp manifestation as 14&6/sec positive spikes is confounded by wakefulness, REM and NREM I stages, and "masked" by the co-occurrence of NREM II and SWS slow waves, and overlapping reactive micro-arousal elements.SIGNIFICANCE: Our study highlighted the overnight profile of hippocampal barques, in relation to the respective profile of their scalp manifestation, the 14&6/sec positive spikes variant.PMID:38042011 | DOI:10.1016/j.clinph.2023.11.008 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - December 2, 2023 Category: Neurology Authors: Vasileios Kokkinos Helweh Hussein Danai Georgia Sakelliadou R Mark Richardson Anto Ι Bagić Alexandra Urban Source Type: research