Intraoperative neuromonitoring as real-time diagnostic for cerebral ischemia in endovascular treatment of ruptured brain aneurysms
CONCLUSIONS: Significant IONM changes during EVT for rIA are associated with an increased risk of PPND.SIGNIFICANCE: IONM can be used confidently as a real time neurophysiological diagnostic guide for impending neurological deficits during EVT treatment of rIA.PMID:38452426 | DOI:10.1016/j.clinph.2024.02.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 7, 2024 Category: Neurology Authors: Abdullah M Al-Qudah Parthasarathy D Thirumala Katherine M Anetakis Donald J Crammond Saleh A Algarni Mohammad AlMajali Varun Shandal Bradley A Gross Michael Lang Nirav R Bhatt Alhamza R Al-Bayati Raul G Nogueira Jeffrey R Balzer Source Type: research

Measurable transitions during seizures in intracranial EEG: A stereoelectroencephalography and SPECT study
CONCLUSIONS: Hypoperfused brain regions were found to indirectly interact with the EZ during the ictal period.SIGNIFICANCE: Our unique study, combining intracranial electrophysiology and perfusion imaging, presents compelling evidence of dynamic changes in directional connectivity between brain regions during the transition from interictal to ictal states.PMID:38452427 | DOI:10.1016/j.clinph.2024.02.022 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 7, 2024 Category: Neurology Authors: Balu Krishnan Simon Tousseyn Kenneth Taylor Guiyun Wu Demitre Serletis Imad Najm Juan Bulacio Andreas V Alexopoulos Source Type: research

Intraoperative neuromonitoring as real-time diagnostic for cerebral ischemia in endovascular treatment of ruptured brain aneurysms
CONCLUSIONS: Significant IONM changes during EVT for rIA are associated with an increased risk of PPND.SIGNIFICANCE: IONM can be used confidently as a real time neurophysiological diagnostic guide for impending neurological deficits during EVT treatment of rIA.PMID:38452426 | DOI:10.1016/j.clinph.2024.02.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 7, 2024 Category: Neurology Authors: Abdullah M Al-Qudah Parthasarathy D Thirumala Katherine M Anetakis Donald J Crammond Saleh A Algarni Mohammad AlMajali Varun Shandal Bradley A Gross Michael Lang Nirav R Bhatt Alhamza R Al-Bayati Raul G Nogueira Jeffrey R Balzer Source Type: research

Measurable transitions during seizures in intracranial EEG: A stereoelectroencephalography and SPECT study
CONCLUSIONS: Hypoperfused brain regions were found to indirectly interact with the EZ during the ictal period.SIGNIFICANCE: Our unique study, combining intracranial electrophysiology and perfusion imaging, presents compelling evidence of dynamic changes in directional connectivity between brain regions during the transition from interictal to ictal states.PMID:38452427 | DOI:10.1016/j.clinph.2024.02.022 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 7, 2024 Category: Neurology Authors: Balu Krishnan Simon Tousseyn Kenneth Taylor Guiyun Wu Demitre Serletis Imad Najm Juan Bulacio Andreas V Alexopoulos Source Type: research

Long-term findings on working memory neural dynamics in healthcare workers after mild COVID-19
CONCLUSIONS: This neural pattern suggests the presence of a decrement of processing resources linked to the encoding of sensory information (N1), followed by the enhanced of the P2 response which could be interpreted as the activation of compensation mechanism in COVID-19 participants.SIGNIFICANCE: The current findings point out that ERPs could serve as valuable neural indices for detecting distinctive patterns in working memory functioning of COVID-19 participants, even in mild cases. However, further research is required to precisely ascertain the long-term cognitive effects of COVID-19 beyond one-year post-infection.PMI...
Source: Clinical Neurophysiology - March 6, 2024 Category: Neurology Authors: David Ferrera Diego Gal án Irene Pel áez Alberto Carpio Mar ía Carmen Martín-Buro Francisco Mercado Source Type: research

Delays in latencies of median-nerve evoked magnetic fields in patients with succinic semialdehyde dehydrogenase deficiency
CONCLUSIONS: The SEF latencies are delayed in patients with SSADHD compared with healthy controls and disease controls.SIGNIFICANCE: This is the first study that compares conduction velocities in the somatosensory pathway in SSADHD, an inherited disorder of GABA metabolism. The longer peak latency implying slower conduction velocity supports the hypothesis that myelin sheath thickness is decreased in SSADHD.PMID:38447494 | DOI:10.1016/j.clinph.2024.02.010 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 6, 2024 Category: Neurology Authors: Teppei Matsubara Sheraz Khan Padmavathi Sundaram Steven Stufflebeam Deniz Aygun Melissa DiBacco Jean-Baptiste Roullet Phillip L Pearl Yoshio Okada Source Type: research

Neural control of blinking
We describe the infra-nuclear apparatus, as well as the supra-nuclear control mechanisms, i.e., how cortical, subcortical, and brainstem structures regulate and coordinate the different types of blinking.PMID:38447495 | DOI:10.1016/j.clinph.2024.02.023 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 6, 2024 Category: Neurology Authors: Matteo Bologna Giulia Paparella Josep Valls-Sol é Mark Hallett Alfredo Berardelli Source Type: research

Whole-body fasciculation detection in amyotrophic lateral sclerosis using motor unit MRI (MUMRI)
CONCLUSION: MUMRI can non-invasively image fasciculation in multiple body regions and appears sensitive to disease progression in individual patients.SIGNIFICANCE: MUMRI has potential as diagnostic tool for ALS.PMID:38448302 | DOI:10.1016/j.clinph.2024.02.016 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 6, 2024 Category: Neurology Authors: Linda Heskamp Matthew G Birkbeck Julie Hall Ian S Schofield James Bashford Timothy L Williams Hugo M De Oliveira Roger G Whittaker Andrew M Blamire Source Type: research

The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
CONCLUSION: Our study adds a new principle to the knowledge of the central processing of a GVS response in healthy subjects. The GVS-safety profile of current up to 2 mA was sufficient to elicit a significant GVS nystagmus response in a head-still position in 63% and after a headshake in 79%. Compared to the GVS head-still condition, a headshake enhanced the GVS-induced nystagmus more than twice.SIGNIFICANCE: The headshake helps to identify GVS-induced nystagmus, which can be weak or absent during the head-still condition.PMID:38432184 | DOI:10.1016/j.clinph.2024.02.018 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Maja Striteska Jan Kremlacek Source Type: research

Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking
CONCLUSION: Our findings show that spontaneous blinking is related to striatal dopamine and has a frequency specific deployment in the STN. This correlation depends on the current movement state such as walking.SIGNIFICANCE: This work indicates that subcortical activity following a motor event as well as the relationship between dopamine and motor events can be dependent on the motor state. Accordingly, disease related changes in brain activity should be assessed during natural movement.PMID:38432185 | DOI:10.1016/j.clinph.2024.02.019 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Liyu Cao Chiara Palmisano Xinyu Chen Ioannis U Isaias Barbara F H ändel Source Type: research

Impacts of education level on Montreal Cognitive Assessment and saccades in community residents from Western China
CONCLUSION: Saccades are less susceptible to the influence of education level when compared to MoCA, making saccade a potentially more suitable cognitive screening tool for rural community populations.SIGNIFICANCE: This study represents a pioneering approach by employing saccade detection within community populations to distinguish cognitive function status.PMID:38432186 | DOI:10.1016/j.clinph.2024.02.017 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Hua Li Anjiao Peng Wanlin Lai Junru Wu Shuming Ji Dan Hu Shujuan Chen Chenxing Zhu Qiulei Hong Mingsha Zhang Lei Chen Source Type: research

The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
CONCLUSION: Our study adds a new principle to the knowledge of the central processing of a GVS response in healthy subjects. The GVS-safety profile of current up to 2 mA was sufficient to elicit a significant GVS nystagmus response in a head-still position in 63% and after a headshake in 79%. Compared to the GVS head-still condition, a headshake enhanced the GVS-induced nystagmus more than twice.SIGNIFICANCE: The headshake helps to identify GVS-induced nystagmus, which can be weak or absent during the head-still condition.PMID:38432184 | DOI:10.1016/j.clinph.2024.02.018 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Maja Striteska Jan Kremlacek Source Type: research

Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking
CONCLUSION: Our findings show that spontaneous blinking is related to striatal dopamine and has a frequency specific deployment in the STN. This correlation depends on the current movement state such as walking.SIGNIFICANCE: This work indicates that subcortical activity following a motor event as well as the relationship between dopamine and motor events can be dependent on the motor state. Accordingly, disease related changes in brain activity should be assessed during natural movement.PMID:38432185 | DOI:10.1016/j.clinph.2024.02.019 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Liyu Cao Chiara Palmisano Xinyu Chen Ioannis U Isaias Barbara F H ändel Source Type: research

Impacts of education level on Montreal Cognitive Assessment and saccades in community residents from Western China
CONCLUSION: Saccades are less susceptible to the influence of education level when compared to MoCA, making saccade a potentially more suitable cognitive screening tool for rural community populations.SIGNIFICANCE: This study represents a pioneering approach by employing saccade detection within community populations to distinguish cognitive function status.PMID:38432186 | DOI:10.1016/j.clinph.2024.02.017 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Hua Li Anjiao Peng Wanlin Lai Junru Wu Shuming Ji Dan Hu Shujuan Chen Chenxing Zhu Qiulei Hong Mingsha Zhang Lei Chen Source Type: research

The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
CONCLUSION: Our study adds a new principle to the knowledge of the central processing of a GVS response in healthy subjects. The GVS-safety profile of current up to 2 mA was sufficient to elicit a significant GVS nystagmus response in a head-still position in 63% and after a headshake in 79%. Compared to the GVS head-still condition, a headshake enhanced the GVS-induced nystagmus more than twice.SIGNIFICANCE: The headshake helps to identify GVS-induced nystagmus, which can be weak or absent during the head-still condition.PMID:38432184 | DOI:10.1016/j.clinph.2024.02.018 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 3, 2024 Category: Neurology Authors: Maja Striteska Jan Kremlacek Source Type: research