The effects of oral contraceptives on resting autonomic function and the autonomic response to physiological stressors: a systematic review
ConclusionOC influence the physiological responses to chemoreflex, mechanoreflex, and metaboreflex activation. In terms of autonomic indices and physiological stressors, there are more inconsistencies within the OC literature, which may be due to estrogen dosage within the OC formulation (i.e., heart rate variability) or the intensity of the stressor (exercise intensity/duration or orthostatic stress). Further research is required to elucidate the effects of OC on these aspects of autonomic function because of the relatively small amount of available research. Furthermore, researchers should more clearly define or stratify...
Source: Clinical Autonomic Research - November 16, 2023 Category: Research Source Type: research

Serotonin reuptake inhibition for the prevention of vasovagal syncope: a systematic review and meta-analysis
ConclusionsSerotonin-specific reuptake inhibitors may be effective in preventing syncope induced by head-up tilt testing and in syncope in the community in randomized, double-blinded clinical trials. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 16, 2023 Category: Research Source Type: research

The effects of oral contraceptives on resting autonomic function and the autonomic response to physiological stressors: a systematic review
ConclusionOC influence the physiological responses to chemoreflex, mechanoreflex, and metaboreflex activation. In terms of autonomic indices and physiological stressors, there are more inconsistencies within the OC literature, which may be due to estrogen dosage within the OC formulation (i.e., heart rate variability) or the intensity of the stressor (exercise intensity/duration or orthostatic stress). Further research is required to elucidate the effects of OC on these aspects of autonomic function because of the relatively small amount of available research. Furthermore, researchers should more clearly define or stratify...
Source: Clinical Autonomic Research - November 16, 2023 Category: Research Source Type: research

Serotonin reuptake inhibition for the prevention of vasovagal syncope: a systematic review and meta-analysis
ConclusionsSerotonin-specific reuptake inhibitors may be effective in preventing syncope induced by head-up tilt testing and in syncope in the community in randomized, double-blinded clinical trials. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 16, 2023 Category: Research Source Type: research

Noninvasive low-level tragus stimulation attenuates inflammation and oxidative stress in acute heart failure
ConclusionIn this proof-of-concept pilot study, in acute decompensated heart failure, neuromodulation was feasible and safe and was associated with a reduction in systemic inflammation and attenuation of coronary endothelial cellular oxidative stress.Clinical trial registrationNCT02898181.Graphical abstract (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 9, 2023 Category: Research Source Type: research

Cholinesterase inhibitors associated with lower rate of mortality in dementia patients with heart failure: a nationwide propensity weighting study
ConclusionsThe results of this retrospective cohort study suggest that ChEIs may be beneficial in reducing all-cause and cardiovascular mortality in patients with dementia with HF. Further research is needed to validate these findings and explore the potential benefits of ChEIs in all patients with HF, including those without dementia. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 8, 2023 Category: Research Source Type: research

Recent updates in autonomic research: new insights into vagal nerve activity during exercise, cardiac autonomic neuropathy and silent myocardial infarction in diabetes, and timing of orthostatic blood pressure change and future risk of dementia
(Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 4, 2023 Category: Research Source Type: research

Inhalation of THC-containing cannabis selectively diminishes cardiac autonomic function in humans
(Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - October 31, 2023 Category: Research Source Type: research

Sex differences in Black Veterans with PTSD: women versus men have higher sympathetic activity, inflammation, and blunted cardiovagal baroreflex sensitivity
ConclusionBlack women with PTSD have higher resting HR and MSNA, greater impairment of cardiovagal BRS and possibly higher inflammation. These findings suggest a higher burden of autonomic and inflammatory derangements in Black women compared to Black men with PTSD. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - October 28, 2023 Category: Research Source Type: research