Orthostatic hypertension —too much of a good thing
(Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - June 30, 2023 Category: Research Source Type: research

Effects of daily artificial gravity training on orthostatic tolerance following 60-day strict head-down tilt bedrest
ConclusionsDaily artificial gravity training on a short-arm centrifuge attenuated the reduction in orthostatic tolerance after 60  days of head-down tilt bedrest. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - June 22, 2023 Category: Research Source Type: research

Associations between physical activity and autonomic function during deep breathing test: the Swedish CArdioPulmonary bioImage Study (SCAPIS)
ConclusionWe report associations between degree of physical activity and indices of autonomic dysfunction in a large population. The relationships were no longer significant after adjustments for heart rate, indicating that the relationship between physical activity and cardiovagal function partly is accounted for by reduced heart rate. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - June 21, 2023 Category: Research Source Type: research

Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population
ConclusionsThis is the first study to demonstrate significant impairment across all subdomains of EQ-5D-5L HrQoL in the POTS cohort as compared with a normative population.Trial registrationACTRN12621001034820 (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - June 20, 2023 Category: Research Source Type: research

A narrative review of the mechanisms and consequences of intermittent hypoxia and the role of advanced analytic techniques in pediatric autonomic disorders
AbstractDisorders of autonomic functions are typically characterized by disturbances in multiple organ systems. These disturbances are often comorbidities of common and rare diseases, such as epilepsy, sleep apnea, Rett syndrome, congenital heart disease or mitochondrial diseases. Characteristic of many autonomic disorders is the association with intermittent hypoxia and oxidative stress, which can cause or exaggerate a variety of other autonomic dysfunctions, making the treatment and management of these syndromes very complex. In this review we discuss the cellular mechanisms by which intermittent hypoxia can trigger a ca...
Source: Clinical Autonomic Research - June 16, 2023 Category: Research Source Type: research

Heart rate variability between hormone phases of the menstrual and oral contraceptive pill cycles of young women
ConclusionsVagal modulation may be increased in the early luteal menstrual cycle phase. Further,oral contraceptive use does not appear to adversely affect this modulation in young, healthy women. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - June 9, 2023 Category: Research Source Type: research

A case of recurring perioperative circulatory arrest: mind the autonomic nervous system
We report the case of an elderly woman who developed recurring episodes of unexplained cardiocirculatory arrest. The index event appeared during surgery to fix a fracture of the ankle and consisted of bradypnea, hypotension and asystole, coherent with a Bezold –Jarisch-like cardioprotective reflex. Classical signs of acute myocardial infarction were absent. Yet, occlusion of the right coronary artery (RCA) was observed and successfully revascularized, whereupon circulatory arrests vanished. We discuss several differential diagnoses. Unexplainable circul atory failure, with sinus bradycardia and arterial hypotension, desp...
Source: Clinical Autonomic Research - June 7, 2023 Category: Research Source Type: research