A case of Wernicke encephalopathy arising in the early stage after the start of hemodialysis
AbstractWernicke encephalopathy (WE) resulting from vitamin B1 (VB1) deficiency is commonly regarded as being associated with a high alcohol intake; however, recently many non-alcohol-related cases have been reported. Herein, we report a case of WE due to VB1 deficiency in the early stage after the start of hemodialysis. The patient was a 79-year-old male recommended for hemodialysis due to chronic renal failure. He was admitted to our hospital due to a hemorrhagic duodenal ulcer, but hemodialysis was started as the result of exacerbation of renal function. After the start of 3-times-weekly hemodialysis, the patient ’s g...
Source: CEN Case Reports - January 6, 2022 Category: Urology & Nephrology Source Type: research
Laparoscopic assisted mini-ECIRS for ectopic kidney lithiasis: A case report and literature review
ConclusionLaparoscopic-assisted mini ECIRS is a viable option for the treatment of ectopic kidney stones. This technique should be considered when anatomical anomalies are encountered, to avoid puncture-related complications. (Source: CEN Case Reports)
Source: CEN Case Reports - January 4, 2022 Category: Urology & Nephrology Source Type: research
A young adult with nephrotic syndrome following COVID-19 vaccination
(Source: CEN Case Reports)
Source: CEN Case Reports - January 4, 2022 Category: Urology & Nephrology Source Type: research
A long-term survival case of Erdheim –Chester disease on maintenance hemodialysis
This report describes an unusual case of Erdheim–Chester disease requiring maintenance hemodialysis that longer prognosis than expected was obtained regardless of multiple organ involvement and no specific treatment after interferon-alpha cessation. (Source: CEN Case Reports)
Source: CEN Case Reports - January 3, 2022 Category: Urology & Nephrology Source Type: research
Metformin-associated lactic acidosis exacerbated by acute kidney injury in an overseas traveler
We report the case of metformin-associated lactic acidosis (MALA) exacerbated by acute kidney injury (AKI) in a 65-year-old Asian American woman who was an overseas traveler. She had vomiting and diarrhea before arriving in Osaka, Japan, from the Philippines. She suffered from worsening respiratory distress, consciousness loss and anuria the day after coming to Japan. When she arrived at our emergency room via ambulance, she appeared to be in a state shock. Arterial blood gas analysis revealed severe lactic acidosis (pH 6.681, PO2 302 Torr under O2 supplementation, PCO2 15 Torr, HCO3−1.7 mmol/L, and lactate 17.00 ...
Source: CEN Case Reports - November 27, 2021 Category: Urology & Nephrology Source Type: research
COVID-19 associated collapsing glomerulopathy presenting as acute kidney injury on chronic kidney disease: a case report and review of the literature
In this report, we present a 49-year-old African American female with a past medical history of chronic kidney disease (CKD) stage 4, hypertension, type 2 diabetes mellitus, recent COVID-19 infection, and a repeat positive blood test for COVID-19 more than 21 days after the initial result, who presented with an AKI on CKD. Renal biopsy revealed a collapsing glomerulopathy. She was started on hemodialysis and did not receive immunosuppressive therapy due to the advanced scaring seen on the renal biopsy. Concerning the pathophysiology of COVID-19-associa ted CG, researchers have postulated different mechanisms such as a di...
Source: CEN Case Reports - November 26, 2021 Category: Urology & Nephrology Source Type: research
A case of acute bromvalerylurea intoxication that was successfully treated with direct hemoperfusion
We report a 21-year-old Japanese woman who was admitted to our hospital in an unconscious state after she had taken 388 tablets of NARON ACE. She was intubated and high flow continuous hemodiafiltration was initiated because her blood pressure remained low, despite continuous intravenous drip infusion. To remove unknown drugs, direct hemoperfusion was performed twice. NARON ACE contains bromvalerylurea, ibuprofen, ethenzamide, and anhydrous caffeine; only the amount of bromvalerylurea was thought to exceed a lethal dose. The plasma concentrations of bromvalerylurea on the first, second, third, and fourth days were 118.9, 4...
Source: CEN Case Reports - November 24, 2021 Category: Urology & Nephrology Source Type: research
Renal recovery following daratumumab, lenalidomide, and dexamethasone therapy in a patient with newly diagnosed dialysis-dependent multiple myeloma
We report the first case of untreated patient with myeloma who had been successfully treated with daratumumab, lenalidomide, and dexamethasone therapy even in dialysis requiring state. Daratumumab may benefit patients with acute kidney injury caused by multiple myeloma, owing to the immediate need of FLC level reduction. Daratumumab and lenalidomide combination therapy could be a valuable treatment option for patients requiring dialysis when bortezomib may be hesitate to use due to severe heart disease. (Source: CEN Case Reports)
Source: CEN Case Reports - November 24, 2021 Category: Urology & Nephrology Source Type: research
A case of C3 glomerulopathy with nephritis-associated plasmin receptor positivity without a history of streptococcal infection
AbstractA 17-year-old lady was diagnosed with proteinuria and microscopic hematuria within the prior 2 years to this presentation. Further tests revealed nephrotic syndrome with hematuria and hypocomplementemia. Renal histopathology showed membranoproliferative glomerulonephritis. Immunostaining and electron microscopy, suggested C3 glomerulonephritis (C3GN). Nephritis-associated plasmin receptor ( NAPlr) and plasmin activity (PA), markers of infection-related glomerulonephritis, were identified in the aforementioned pathology specimens. There are several reports suggesting a causal relationship between group A streptoco...
Source: CEN Case Reports - November 19, 2021 Category: Urology & Nephrology Source Type: research
A case of a hemodialysis patient with secondary hyperparathyroidism who was resistant to etelcalcetide treatment but not to cinacalcet hydrochloride
We report a first case of a hemodialysis (HD) patient with secondary hyperparathyroidism (SHPT), in whom cinacalcet, but not etelcalcetide, could reduce serum intact PTH (i-PTH) levels. A HD patient received total parathyroidectomy (PTx) with auto-transplantation 16 years earlier. Due to SHPT relapse, cinacalcet was started at 7 years after PTx. His i-PTH levels had been controlled with both 75–100 mg of cinacalcet and 4.5 μg/week of calcitriol for a year before switching from cinacalcet to etelcalcetide. At 1 month following the switch, his serum i-PT H level increased to 716 pg/mL. The dose of etelcalcetide was...
Source: CEN Case Reports - November 17, 2021 Category: Urology & Nephrology Source Type: research
A case of smoldering antineutrophil cytoplasmic antibody-associated vasculitis development during the course of primary Sj ögren’s syndrome
AbstractVarious forms of glomerular lesions have been described in primary Sj ögren’s syndrome (pSjS); however, myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is rarely reported, and the disease onset and clinical course of ANCA-associated vasculitis (AAV) complicated by pSjS are not well understood. A 51-year-old woman was referred to our hospital because of mild proteinuria and microscopic hematuria. She fulfilled the classification criteria for pSjS. We performed a kidney biopsy; however, it revealed no characteristic findings for pSjS, vasculitis, or other autoimmune diseases,...
Source: CEN Case Reports - November 17, 2021 Category: Urology & Nephrology Source Type: research
New-onset pediatric nephrotic syndrome following Pfizer-BioNTech SARS-CoV-2 vaccination: a case report and literature review
AbstractVarious new vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been rapidly developed. The new onset and recurrence of nephrotic syndrome triggered by some vaccines have been documented and several adult cases of minimal change nephrotic syndrome newly developing after SARS-CoV-2 vaccination have been reported. However, no reports of pediatric cases have been published. Indications for SARS-CoV-2 vaccines have been expanded to those as young as 12 years old and vaccination of children has just started in Japan. We encountered a 15-year-old boy without underlying disease who newly d...
Source: CEN Case Reports - November 15, 2021 Category: Urology & Nephrology Source Type: research
Recurrent lupus nephritis in renal allograft triggered by pregnancy
AbstractHerein we report the case of a 37-year-old woman with recurrence of lupus nephritis (LN) in a renal allograft during pregnancy. She had developed end-stage renal disease due to LN and was put on hemodialysis at the age of 26 years. She underwent kidney transplantation at the age 28 years. Maintenance immunosuppressants included methylprednisolone, tacrolimus, and mycophenolate mofetil, which were changed to azathioprine when she desired pregnancy. The renal allograft function remained stable and seemingly disease-fre e until proteinuria and functional decline occurred during the pregnancy (age: 34 years). The b...
Source: CEN Case Reports - November 11, 2021 Category: Urology & Nephrology Source Type: research
A case of systemic sarcoidosis with mesangial proliferative glomerulonephritis showing predominant deposition of IgG in the mesangial region
AbstractA 37-year-old African –British man was referred to our hospital for detailed examination because of persistent fever, swelling and pain in both ankle joints, and blurred vision for two months. Inguinal lymph node biopsy showed a large number of epithelioid granulomas without necrosis. Granulomatous anterior uveitis, ne phropathy, high serum angiotensin-converting enzyme activity, and high serum-soluble interleukin-2 receptor were observed, and the diagnosis of systemic sarcoidosis was made. His serum creatinine was 1.4 mg/dL and hematuria, leukocyturia, and urine protein were also seen. The renal biopsy finding ...
Source: CEN Case Reports - November 9, 2021 Category: Urology & Nephrology Source Type: research
Utility of portal venous Doppler in the assessment of fluid status in end-stage kidney disease: think beyond IVC ultrasound
(Source: CEN Case Reports)
Source: CEN Case Reports - November 9, 2021 Category: Urology & Nephrology Source Type: research
