The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers
Cancer Gene Therapy, Published online: 16 March 2024; doi:10.1038/s41417-024-00763-xThe pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 16, 2024 Category: Cancer & Oncology Authors: Domenica Ronchetti Valentina Traini Ilaria Silvestris Giuseppina Fabbiano Francesco Passamonti Niccol ò Bolli Elisa Taiana Source Type: research

MISEV2023: Shaping the Future of EV Research by Enhancing Rigour, Reproducibility and Transparency
Cancer Gene Therapy, Published online: 14 March 2024; doi:10.1038/s41417-024-00759-7MISEV2023: Shaping the Future of EV Research by Enhancing Rigour, Reproducibility and Transparency (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 14, 2024 Category: Cancer & Oncology Authors: Mark Samuels Georgios Giamas Source Type: research

The integrate profiling of single-cell and spatial transcriptome RNA-seq reveals tumor heterogeneity, therapeutic targets, and prognostic subtypes in ccRCC
Cancer Gene Therapy, Published online: 13 March 2024; doi:10.1038/s41417-024-00755-xThe integrate profiling of single-cell and spatial transcriptome RNA-seq reveals tumor heterogeneity, therapeutic targets, and prognostic subtypes in ccRCC (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 13, 2024 Category: Cancer & Oncology Authors: Yanlong Zhang Xuefeng Huang Minghang Yu Menghan Zhang Li Zhao Yong Yan Liyun Zhang Xi Wang Source Type: research

Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT
Cancer Gene Therapy, Published online: 13 March 2024; doi:10.1038/s41417-024-00753-zCaffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 13, 2024 Category: Cancer & Oncology Authors: Ying-Yu Kuo Chieh Huo Chia-Yang Li Chih-Pin Chuu Source Type: research

Romidepsin exhibits anti-esophageal squamous cell carcinoma activity through the DDIT4-mTORC1 pathway
Cancer Gene Therapy, Published online: 13 March 2024; doi:10.1038/s41417-024-00760-0Romidepsin exhibits anti-esophageal squamous cell carcinoma activity through the DDIT4-mTORC1 pathway (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 13, 2024 Category: Cancer & Oncology Authors: Wei-Feng Xia Xiao-Li Zheng Wen-Yi Liu Yu-Tang Huang Chun-Jie Wen Hong-Hao Zhou Qing-Chen Wu Lan-Xiang Wu Source Type: research

Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis
Cancer Gene Therapy, Published online: 13 March 2024; doi:10.1038/s41417-024-00751-1Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 13, 2024 Category: Cancer & Oncology Authors: Marcela S. Werner Shweta Aras Ashleigh R. Morgan Jillian Roamer Nesteene J. Param Kanyin Olagbegi R. Jason Lamontagne Jenny A. Greig James M. Wilson Source Type: research

Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy
Cancer Gene Therapy, Published online: 11 March 2024; doi:10.1038/s41417-024-00757-9Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 11, 2024 Category: Cancer & Oncology Authors: Haruki Horiguchi Tsuyoshi Kadomatsu Tomoya Yamashita Shinsei Yumoto Taichi Horino Michio Sato Kazutoyo Terada Keishi Miyata Yuki Ichigozaki Toshihiro Kimura Satoshi Fukushima Toshiro Moroishi Yuichi Oike Source Type: research

Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway
Cancer Gene Therapy, Published online: 11 March 2024; doi:10.1038/s41417-024-00754-yHeparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 11, 2024 Category: Cancer & Oncology Authors: Fengyan Yuan Huiqin Zhou Chongyang Liu Yi Wang Jing Quan Jie Liu Hao Li Mark von Itzstein Xing Yu Source Type: research

Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer
Cancer Gene Therapy, Published online: 08 March 2024; doi:10.1038/s41417-024-00743-1Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 8, 2024 Category: Cancer & Oncology Authors: Bangting Wang Shijie Zhang Haiyang Wang Min Wang Yuwen Tao Mujie Ye Zhining Fan Yan Wang Li Liu Source Type: research

CAR T therapies in multiple myeloma: unleashing the future
Cancer Gene Therapy, Published online: 04 March 2024; doi:10.1038/s41417-024-00750-2CAR T therapies in multiple myeloma: unleashing the future (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 4, 2024 Category: Cancer & Oncology Authors: Mohsen Sheykhhasan Amirhossein Ahmadieh-Yazdi Rosario Vicidomini Naresh Poondla Hamid Tanzadehpanah Ashkan Dirbaziyan Hanie Mahaki Hamed Manoochehri Naser Kalhor Paola Dama Source Type: research

Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines
Cancer Gene Therapy, Published online: 01 March 2024; doi:10.1038/s41417-024-00745-zIdentification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 1, 2024 Category: Cancer & Oncology Authors: Liying Yang Kohei Kumegawa Sumito Saeki Tomoyoshi Nakadai Reo Maruyama Source Type: research

Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma
Cancer Gene Therapy, Published online: 01 March 2024; doi:10.1038/s41417-024-00740-4Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - March 1, 2024 Category: Cancer & Oncology Authors: Xingdong Wang Yizhi Ge Yuting Hou Xiaodong Wang Zhengcun Yan Yuping Li Lun Dong Lei She Can Tang Min Wei Hengzhu Zhang Source Type: research

Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer
Cancer Gene Therapy, Published online: 29 February 2024; doi:10.1038/s41417-024-00748-wDual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - February 29, 2024 Category: Cancer & Oncology Authors: Kei Kudo Yoshimi Endo Greer Teruhiko Yoshida Brittney S. Harrington Soumya Korrapati Yusuke Shibuya Leah Henegar Jeffrey B. Kopp Takeo Fujii Stanley Lipkowitz Christina M. Annunziata Source Type: research

Genetic mutation patterns among glioblastoma patients in the Taiwanese population – insights from a single institution retrospective study
Cancer Gene Therapy, Published online: 28 February 2024; doi:10.1038/s41417-024-00746-yGenetic mutation patterns among glioblastoma patients in the Taiwanese population – insights from a single institution retrospective study (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - February 28, 2024 Category: Cancer & Oncology Authors: Yu-Fen Huang Ming-Tsang Chiao Tzu-Hung Hsiao Yong-Xiang Zhan Tse-Yu Chen Chung-Hsin Lee Szu-Yuan Liu Chih-Hsiang Liao Wen-Yu Cheng Chun-Ming Yen Chih-Ming Lai Jun-Peng Chen Chiung-Chyi Shen Meng-Yin Yang Source Type: research

A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma
Cancer Gene Therapy, Published online: 26 February 2024; doi:10.1038/s41417-024-00749-9A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - February 26, 2024 Category: Cancer & Oncology Authors: Nikolas Herold Source Type: research