Neddylation of insulin receptor substrate acts as a bona fide regulator of insulin signaling and its implications for cancer cell migration
Cancer Gene Therapy, Published online: 25 January 2024; doi:10.1038/s41417-024-00729-zNeddylation of insulin receptor substrate acts as a bona fide regulator of insulin signaling and its implications for cancer cell migration (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 25, 2024 Category: Cancer & Oncology Authors: Jun Bum Park Geon Ho Moon Ara Cho Minji Kwon Jong-Wan Park Eugene C. Yi Haeryoung Kim Junji Fukuda Cheol Kwak Young-Gyu Ko Yang-Sook Chun Source Type: research

METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1
Cancer Gene Therapy, Published online: 24 January 2024; doi:10.1038/s41417-024-00731-5METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1 (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 24, 2024 Category: Cancer & Oncology Authors: Rui Yang Cheng Yang Danjie Su Yang Song Jie Min Zhixin Qian Xiangjing Shen Junqiang Li Haichuan Su Source Type: research

LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling
Cancer Gene Therapy, Published online: 24 January 2024; doi:10.1038/s41417-024-00726-2LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 24, 2024 Category: Cancer & Oncology Authors: Shaobo Yu Xin Gao Sidi Liu Xiangjun Sha Siyuan Zhang Xinmiao Zhang Dongsheng Sun Xingming Jiang Source Type: research

GRIN2A mutation is a novel indicator of stratifying beneficiaries of immune checkpoint inhibitors in multiple cancers
Cancer Gene Therapy, Published online: 24 January 2024; doi:10.1038/s41417-024-00730-6GRIN2A mutation is a novel indicator of stratifying beneficiaries of immune checkpoint inhibitors in multiple cancers (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 24, 2024 Category: Cancer & Oncology Authors: Gan-xun Li Rui-zhi Chang Tong-tong Liu Guan-nan Jin Kan Lu Tu-ying Yong Zifu Li Ji-hong Liu Bixiang Zhang Wan-guang Zhang Ze-yang Ding Source Type: research

The safety and efficacy of systemic delivery of a new liver-de-targeted TGFβ signaling inhibiting adenovirus in an immunocompetent triple negative mouse mammary tumor model
Cancer Gene Therapy, Published online: 24 January 2024; doi:10.1038/s41417-024-00735-1The safety and efficacy of systemic delivery of a new liver-de-targeted TGFβ signaling inhibiting adenovirus in an immunocompetent triple negative mouse mammary tumor model (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 24, 2024 Category: Cancer & Oncology Authors: Soon Cheon Shin Renee E. Vickman Beniamin Filimon Yuefeng Yang Zebin Hu Kathy A. Mangold Bellur S. Prabhakar Hans Schreiber Weidong Xu Source Type: research

Retinoids and EZH2 inhibitors cooperate to orchestrate anti-oncogenic effects on bladder cancer cells
Cancer Gene Therapy, Published online: 17 January 2024; doi:10.1038/s41417-024-00725-3Retinoids and EZH2 inhibitors cooperate to orchestrate anti-oncogenic effects on bladder cancer cells (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 17, 2024 Category: Cancer & Oncology Authors: Gizem Ozgun Tutku Yaras Burcu Akman G ülden Özden-Yılmaz Nick Landman G ökhan Karakülah Maarten van Lohuizen Serif Senturk Serap Erkek-Ozhan Source Type: research

Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents
Cancer Gene Therapy, Published online: 10 January 2024; doi:10.1038/s41417-023-00715-xRedefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 10, 2024 Category: Cancer & Oncology Authors: Eileena F. Giurini Aishvarya Godla Kajal H. Gupta Source Type: research

A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation
Cancer Gene Therapy, Published online: 04 January 2024; doi:10.1038/s41417-023-00717-9A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 4, 2024 Category: Cancer & Oncology Authors: Su He Wang Zhengyi Cao Mohammad Farazuddin Jesse Chen Katarzyna W. Janczak Shengzhuang Tang Jayme Cannon James R. Baker Jr Source Type: research

Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis
Cancer Gene Therapy, Published online: 04 January 2024; doi:10.1038/s41417-023-00723-xSleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 4, 2024 Category: Cancer & Oncology Authors: Naoko Iida Yukari Muranaka Jun Won Park Shigeki Sekine Neal G. Copeland Nancy A. Jenkins Yuichi Shiraishi Masanobu Oshima Haruna Takeda Source Type: research

Targeting paraptosis in cancer: opportunities and challenges
Cancer Gene Therapy, Published online: 04 January 2024; doi:10.1038/s41417-023-00722-yTargeting paraptosis in cancer: opportunities and challenges (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - January 4, 2024 Category: Cancer & Oncology Authors: Fangquan Chen Hu Tang Xiutao Cai Junhao Lin Limin Xiang Rui Kang Jiao Liu Daolin Tang Source Type: research

Comparative study on genomic and epigenomic profiles of retinoblastoma or tuberous sclerosis complex via nanopore sequencing and a joint screening framework
Cancer Gene Therapy, Published online: 25 December 2023; doi:10.1038/s41417-023-00714-yComparative study on genomic and epigenomic profiles of retinoblastoma or tuberous sclerosis complex via nanopore sequencing and a joint screening framework (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - December 25, 2023 Category: Cancer & Oncology Authors: Junting Wang Chengyue Zhang Li Zhang Hong-juan Yao Xiaohong Liu Yuchen Shi Junyang Zhao Xiaochen Bo Hebing Chen Liang Li Source Type: research

USP30 promotes the progression of breast cancer by stabilising Snail
Cancer Gene Therapy, Published online: 25 December 2023; doi:10.1038/s41417-023-00718-8USP30 promotes the progression of breast cancer by stabilising Snail (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - December 25, 2023 Category: Cancer & Oncology Authors: Kai Sun Shichong Liao Xinrui Yao Feng Yao Source Type: research

BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors
Cancer Gene Therapy, Published online: 25 December 2023; doi:10.1038/s41417-023-00720-0BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - December 25, 2023 Category: Cancer & Oncology Authors: Anthony P. Conley Christina L. Roland Alberto Bessudo Brian R. Gastman Victoria M. Villaflor Christopher Larson Tony R. Reid Scott Caroen Bryan Oronsky Meaghan Stirn Jeannie Williams Erica Burbano Angelique Coyle Minal A. Barve Naveed Wagle Nacer Abrouk S Source Type: research

STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient
Cancer Gene Therapy, Published online: 22 December 2023; doi:10.1038/s41417-023-00719-7STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - December 22, 2023 Category: Cancer & Oncology Authors: Shubing Zhang Jinhua Yan Lan He Zhiping Jiang Hao Jiang Source Type: research

TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling
Cancer Gene Therapy, Published online: 22 December 2023; doi:10.1038/s41417-023-00716-wTSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - December 22, 2023 Category: Cancer & Oncology Authors: Ming-Dian Wang Hui-Ting Li Li-Xia Peng Yan Mei Li-Sheng Zheng Chang-Zhi Li Dong-Fang Meng Yan-Hong Lang Liang Xu Xing-Si Peng Zhi-Jie Liu De-Huan Xie Ling-Ling Guo Mao-Guang Ma Liu-Yan Ding Bi-Jun Huang Yun Cao Chao-Nan Qian Source Type: research