CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages
Cancer Gene Therapy, Published online: 23 August 2022; doi:10.1038/s41417-022-00515-9CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 23, 2022 Category: Cancer & Oncology Authors: Jia-Bin Wang You-Xin Gao Yin-Hua Ye Tong-Xing Lin Ping Li Jian-Xian Lin Qi-Yue Chen Long-Long Cao Mi Lin Ru-Hong Tu Ju-Li Lin Ze-Ning Huang Hua-Long Zheng Jian-Wei Xie Chao-Hui Zheng Chang-Ming Huang Source Type: research

Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis
Cancer Gene Therapy, Published online: 23 August 2022; doi:10.1038/s41417-022-00522-wCreation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 23, 2022 Category: Cancer & Oncology Authors: Minori Tamai Shinichi Fujisawa Thao T. T. Nguyen Chiaki Komatsu Keiko Kagami Kenji Kamimoto Kohei Omachi Shin Kasai Daisuke Harama Atsushi Watanabe Koshi Akahane Kumiko Goi Kazuhito Naka Tadashi Kaname Takanori Teshima Takeshi Inukai Source Type: research

Regulation of tumor metabolism by post translational modifications on metabolic enzymes
Cancer Gene Therapy, Published online: 23 August 2022; doi:10.1038/s41417-022-00521-xRegulation of tumor metabolism by post translational modifications on metabolic enzymes (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 23, 2022 Category: Cancer & Oncology Authors: Abhisha Sawant Dessai Poonam Kalhotra Aaron T. Novickis Subhamoy Dasgupta Source Type: research

Hidden patterns of gene expression provide prognostic insight for colorectal cancer
Cancer Gene Therapy, Published online: 18 August 2022; doi:10.1038/s41417-022-00520-yHidden patterns of gene expression provide prognostic insight for colorectal cancer (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 18, 2022 Category: Cancer & Oncology Authors: Dongsan Kim Kwang-Hyun Cho Source Type: research

The cross-talk of cancer-associated fibroblasts assist in prognosis and immunotherapy in patients with breast carcinoma
Cancer Gene Therapy, Published online: 10 August 2022; doi:10.1038/s41417-022-00514-wThe cross-talk of cancer-associated fibroblasts assist in prognosis and immunotherapy in patients with breast carcinoma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 10, 2022 Category: Cancer & Oncology Authors: Xuyu Gu Shiya Zheng Haifeng Zhang Xiaotong Sun Qin Zhou Source Type: research

Targeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling
Cancer Gene Therapy, Published online: 01 August 2022; doi:10.1038/s41417-022-00506-wTargeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 1, 2022 Category: Cancer & Oncology Authors: Qing Liu Bosen You Jialin Meng Chi-Ping Huang Guanglu Dong Ronghao Wang Fuju Chou Shan Gao Chawnshang Chang Shuyuan Yeh Wanhai Xu Source Type: research

Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner
Cancer Gene Therapy, Published online: 28 July 2022; doi:10.1038/s41417-022-00513-xEpigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 28, 2022 Category: Cancer & Oncology Authors: Michelle L. Woods Astrid Weiss Anna M. Sokol Johannes Graumann Thomas Boettger Antje M. Richter Ralph T. Schermuly Reinhard H. Dammann Source Type: research

Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1
Cancer Gene Therapy, Published online: 28 July 2022; doi:10.1038/s41417-022-00508-8Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1 (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 28, 2022 Category: Cancer & Oncology Authors: Fan Yang Lin Li Zhenzhen Mu Pengyue Liu Ying Wang Yue Zhang Xiuping Han Source Type: research

Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma
Cancer Gene Therapy, Published online: 28 July 2022; doi:10.1038/s41417-022-00510-0Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 28, 2022 Category: Cancer & Oncology Authors: Jin Liu Binwen Sun Kun Guo Zhou Yang Yidan Zhao Mingwei Gao Zeli Yin Keqiu Jiang Chengyong Dong Zhenming Gao Mingliang Ye Jing Liu Liming Wang Source Type: research

CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma
Cancer Gene Therapy, Published online: 28 July 2022; doi:10.1038/s41417-022-00512-yCYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 28, 2022 Category: Cancer & Oncology Authors: Chen Zhang Jinqiu Zhao Jie Zhao Bohao Liu Wenbin Tang Yi Liu Wenxiang Huang Steven A. Weinman Zhuan Li Source Type: research

The combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion
Cancer Gene Therapy, Published online: 25 July 2022; doi:10.1038/s41417-022-00511-zThe combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 25, 2022 Category: Cancer & Oncology Authors: Azusa Mayumi Toshihiro Tomii Takuyo Kanayama Takashi Mikami Kuniaki Tanaka Hiroo Ueno Hideki Yoshida Itaru Kato Machiko Kawamura Tatsutoshi Nakahata Junko Takita Hajime Hosoi Toshihiko Imamura Source Type: research

ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications
Cancer Gene Therapy, Published online: 22 July 2022; doi:10.1038/s41417-022-00505-xARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 22, 2022 Category: Cancer & Oncology Authors: Pallavi Shukla Prerana Dange Bhabani Shankar Mohanty Nikhil Gadewal Pradip Chaudhari Rajiv Sarin Source Type: research

Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus
Cancer Gene Therapy, Published online: 22 July 2022; doi:10.1038/s41417-022-00507-9Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 22, 2022 Category: Cancer & Oncology Authors: Tom J. Harryvan Matteo Golo Nicole Dam Mark J. A. Schoonderwoerd Elham Aida Farshadi Marten Hornsveld Rob C. Hoeben Lukas J. A. C. Hawinkels Vera Kemp Source Type: research

CpG-binding protein CFP1 promotes ovarian cancer cell proliferation by regulating BST2 transcription
Cancer Gene Therapy, Published online: 21 July 2022; doi:10.1038/s41417-022-00503-zCpG-binding protein CFP1 promotes ovarian cancer cell proliferation by regulating BST2 transcription (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 21, 2022 Category: Cancer & Oncology Authors: Liu-Qing Yang Han-Yin Hu Yao Han Ze-Yi Tang Jie Gao Qi-Yin Zhou Yi-Xuan Liu Hao-Sa Chen Tu-Nan Xu Lei Ao Ying Xu Xuan Che Ya-Bo Jiang Chun-Wei Xu Xian-Chao Zhang Yu-Xin Jiang Michal Heger Xiao-Min Wang Shu-Qun Cheng Wei-Wei Pan Source Type: research

Correction to: Targeting CLK4 inhibits the metastasis and progression of breast cancer by inactivating TGF-β pathway
Cancer Gene Therapy, Published online: 20 July 2022; doi:10.1038/s41417-022-00509-7Correction to: Targeting CLK4 inhibits the metastasis and progression of breast cancer by inactivating TGF-β pathway (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - July 20, 2022 Category: Cancer & Oncology Authors: Eunji Kang Kanggeon Kim Sook Young Jeon Ji Gwang Jung Hong-Kyu Kim Han-Byoel Lee Wonshik Han Source Type: research