SMYD3 regulates gastric cancer progression and macrophage polarization through EZH2 methylation
Cancer Gene Therapy, Published online: 20 September 2022; doi:10.1038/s41417-022-00535-5SMYD3 regulates gastric cancer progression and macrophage polarization through EZH2 methylation (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 20, 2022 Category: Cancer & Oncology Authors: Peng Wang Liang Zhao Yiqi Rui Yongbin Ding Source Type: research

m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis
Cancer Gene Therapy, Published online: 20 September 2022; doi:10.1038/s41417-022-00526-6m6A-modified circFOXK2 targets GLUT1 to accelerate the aerobic glycolysis of oral squamous cell carcinoma. (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 20, 2022 Category: Cancer & Oncology Authors: Yameng Cui Jingwen Liu Lina Liu Xiaozhou Ma Yu Gui Hao Liu Wei Zhao Source Type: research

Retraction Note: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction
Cancer Gene Therapy, Published online: 20 September 2022; doi:10.1038/s41417-022-00536-4Retraction Note: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 20, 2022 Category: Cancer & Oncology Authors: Zhicheng Yao Shida Yang Hongyou Zhao Huike Yang Xin Jiang Source Type: research

CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines
Cancer Gene Therapy, Published online: 19 September 2022; doi:10.1038/s41417-022-00532-8CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 19, 2022 Category: Cancer & Oncology Authors: Yuichiro Kaibori Daisuke Nagakubo Source Type: research

YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma
Cancer Gene Therapy, Published online: 19 September 2022; doi:10.1038/s41417-022-00533-7Briefly, YAP 3′UTR is m5C modified under the promotion of NSUN2 and ALYREF, and this modification increases YAP mRNA stability and inhibits nearby m6A modification and miR-582-3p binding. Furthermore, YAP stimulates seven exosome biogenesis, transport and release-related genes including HRS, PLD2, RAB2B, RAB27A, RAB27B, VAMP and ATG7 in a Mycn- and SOX10-dependent manner. (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 19, 2022 Category: Cancer & Oncology Authors: Wenjun Yu Congcong Zhang Yikun Wang Xiaoting Tian Yayou Miao Fanyu Meng Lifang Ma Xiao Zhang Jinjing Xia Source Type: research

Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
Cancer Gene Therapy, Published online: 18 September 2022; doi:10.1038/s41417-022-00524-8Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 18, 2022 Category: Cancer & Oncology Authors: Mohammad Salik Zeya Ansari Venturina Stagni Angela Iuzzolino Dante Rotili Antonello Mai Donatella Del Bufalo Patrizia Lavia Francesca Degrassi Daniela Trisciuoglio Source Type: research

Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function
Cancer Gene Therapy, Published online: 16 September 2022; doi:10.1038/s41417-022-00531-9Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 16, 2022 Category: Cancer & Oncology Authors: Hannah Weisser Tamara G öbel G. Melissa Krishnathas Marius Krei ß Carlo Angioni Duran S ürün Dominique Thomas Tobias Schmid Ann-Kathrin H äfner Astrid S. Kahnt Source Type: research

MCPIP1 Suppresses the NF-κB Signaling Pathway Through Negative Regulation of K63-Linked Ubiquitylation of TRAF6 in Colorectal Cancer
Cancer Gene Therapy, Published online: 09 September 2022; doi:10.1038/s41417-022-00528-4MCPIP1 Suppresses the NF-κB Signaling Pathway Through Negative Regulation of K63-Linked Ubiquitylation of TRAF6 in Colorectal Cancer (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 9, 2022 Category: Cancer & Oncology Authors: Wen Ye Yachao Cui Jian Rong Wenlin Huang Zhousan Zheng Anqi Li Yingchang Li Source Type: research

Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth
Cancer Gene Therapy, Published online: 08 September 2022; doi:10.1038/s41417-022-00527-5Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 8, 2022 Category: Cancer & Oncology Authors: Makoto Horikawa Shinichiro Koizumi Tomoya Oishi Taisuke Yamamoto Masashi Ikeno Masahiko Ito Tomohiro Yamasaki Shinji Amano Tetsuro Sameshima Yasuyuki Mitani Yoshihiro Otani Yuanqing Yan Tetsuro Suzuki Hiroki Namba Kazuhiko Kurozumi Source Type: research

Overcoming biophysical barriers with innovative therapeutic delivery approaches
Cancer Gene Therapy, Published online: 08 September 2022; doi:10.1038/s41417-022-00529-3Overcoming biophysical barriers with innovative therapeutic delivery approaches (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 8, 2022 Category: Cancer & Oncology Authors: Swathi Pavuluri Rahul A. Sheth Source Type: research

Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT
Cancer Gene Therapy, Published online: 05 September 2022; doi:10.1038/s41417-022-00517-7Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 5, 2022 Category: Cancer & Oncology Authors: Yan Zheng Huiqing Jia Ping Wang Litong Liu Zhaoxv Chen Xiaoming Xing Jin Wang Xiaohua Tan Chengqin Wang Source Type: research

ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer
Cancer Gene Therapy, Published online: 02 September 2022; doi:10.1038/s41417-022-00525-7ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - September 2, 2022 Category: Cancer & Oncology Authors: Xiaoli Liu Junhua Zhang Shuang Ju Lu Liu Yu Sun Lingyu Guo Qianwei Zhen Sai Han Wei Lu Youzhong Zhang Source Type: research

Correction: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4
Cancer Gene Therapy, Published online: 29 August 2022; doi:10.1038/s41417-022-00519-5Correction: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4 (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 29, 2022 Category: Cancer & Oncology Authors: Tianzhen Hu Chengyun Pan Tianzhuo Zhang Ming Ni Weili Wang Siyu Zhang Ying Chen Jishi Wang Qin Fang Source Type: research

High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion
Cancer Gene Therapy, Published online: 29 August 2022; doi:10.1038/s41417-022-00518-6High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 29, 2022 Category: Cancer & Oncology Authors: Ana Carolina Caballero Laura Escrib à-Garcia Paula Pujol-Fern ández Eva Escudero-L ópez Cristina Ujald ón-Miró Rosanna Montserrat-Torres Jorge Sierra Carmen Alvarez-Fern ández Javier Briones Source Type: research

Correction to: MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state
Cancer Gene Therapy, Published online: 25 August 2022; doi:10.1038/s41417-022-00523-9Correction to: MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - August 25, 2022 Category: Cancer & Oncology Authors: Wen Cai Zhang Nicholas Skiados Fareesa Aftab Cerena Moreno Luis Silva Paul Joshua Anthony Corbilla John M. Asara Aaron N. Hata Frank J. Slack Source Type: research