Is there a link between elevated C-reactive protein levels and specific breast cancer molecular subtypes?
Breast. 2023 Dec 9;73:103621. doi: 10.1016/j.breast.2023.103621. Online ahead of print.NO ABSTRACTPMID:38096710 | DOI:10.1016/j.breast.2023.103621 (Source: Breast)
Source: Breast - December 14, 2023 Category: Cancer & Oncology Authors: Kadri Altundag Source Type: research
Male breast cancer: No evidence for mosaic BRCA1 promoter methylation involvement
Breast. 2023 Dec 10;73:103620. doi: 10.1016/j.breast.2023.103620. Online ahead of print.ABSTRACTBreast cancers (BC) are rare in men and are often caused by constitutional predisposing factors. In women, mosaic BRCA1 promoter methylations (MBPM) are frequent events, detected in 4-8% of healthy subjects. This constitutional epimutation increases risk of early-onset and triple-negative BC. However, the role of MBPM in male BC predisposition has never been assessed. We screened 40 blood samples from men affected by BC, and performed extensive tumour analysis on MBPM-positive patients. We detected two patients carrying MBPM. Su...
Source: Breast - December 14, 2023 Category: Cancer & Oncology Authors: Mathias Schwartz Sabrina Ibadioune Sophie Vacher Marie-Charlotte Villy Olfa Trabelsi-Grati Jessica Le Gall Sandrine M Caputo H élène Delhomelle Mathilde Warcoin Virginie Moncoutier Christine Bourneix Nadia Boutry-Kryza Antoine De Pauw Marc-Henri Stern B Source Type: research
Digital breast tomosynthesis versus X-ray of the breast specimen for intraoperative margin assessment: A randomized trial
CONCLUSIONS: No difference was found in the number of re-operations or in diagnostic accuracy to predict histopathological margin status between DBT and X-ray groups. DCIS outside the tumor showed the highest risk of re-operation. Intraoperative methods with improved visualization of DCIS are needed to obtain tumor free margins in BCS.PMID:38064928 | DOI:10.1016/j.breast.2023.103616 (Source: Breast)
Source: Breast - December 8, 2023 Category: Cancer & Oncology Authors: Irina Palimaru Manhoobi Trine Tramm S øren Redsted Anne Bodilsen Leslie Foldager Peer Christiansen Source Type: research
Digital breast tomosynthesis versus X-ray of the breast specimen for intraoperative margin assessment: A randomized trial
CONCLUSIONS: No difference was found in the number of re-operations or in diagnostic accuracy to predict histopathological margin status between DBT and X-ray groups. DCIS outside the tumor showed the highest risk of re-operation. Intraoperative methods with improved visualization of DCIS are needed to obtain tumor free margins in BCS.PMID:38064928 | DOI:10.1016/j.breast.2023.103616 (Source: Breast)
Source: Breast - December 8, 2023 Category: Cancer & Oncology Authors: Irina Palimaru Manhoobi Trine Tramm S øren Redsted Anne Bodilsen Leslie Foldager Peer Christiansen Source Type: research
Digital breast tomosynthesis versus X-ray of the breast specimen for intraoperative margin assessment: A randomized trial
CONCLUSIONS: No difference was found in the number of re-operations or in diagnostic accuracy to predict histopathological margin status between DBT and X-ray groups. DCIS outside the tumor showed the highest risk of re-operation. Intraoperative methods with improved visualization of DCIS are needed to obtain tumor free margins in BCS.PMID:38064928 | DOI:10.1016/j.breast.2023.103616 (Source: Breast)
Source: Breast - December 8, 2023 Category: Cancer & Oncology Authors: Irina Palimaru Manhoobi Trine Tramm S øren Redsted Anne Bodilsen Leslie Foldager Peer Christiansen Source Type: research
Digital breast tomosynthesis versus X-ray of the breast specimen for intraoperative margin assessment: A randomized trial
CONCLUSIONS: No difference was found in the number of re-operations or in diagnostic accuracy to predict histopathological margin status between DBT and X-ray groups. DCIS outside the tumor showed the highest risk of re-operation. Intraoperative methods with improved visualization of DCIS are needed to obtain tumor free margins in BCS.PMID:38064928 | DOI:10.1016/j.breast.2023.103616 (Source: Breast)
Source: Breast - December 8, 2023 Category: Cancer & Oncology Authors: Irina Palimaru Manhoobi Trine Tramm S øren Redsted Anne Bodilsen Leslie Foldager Peer Christiansen Source Type: research
Digital breast tomosynthesis versus X-ray of the breast specimen for intraoperative margin assessment: A randomized trial
CONCLUSIONS: No difference was found in the number of re-operations or in diagnostic accuracy to predict histopathological margin status between DBT and X-ray groups. DCIS outside the tumor showed the highest risk of re-operation. Intraoperative methods with improved visualization of DCIS are needed to obtain tumor free margins in BCS.PMID:38064928 | DOI:10.1016/j.breast.2023.103616 (Source: Breast)
Source: Breast - December 8, 2023 Category: Cancer & Oncology Authors: Irina Palimaru Manhoobi Trine Tramm S øren Redsted Anne Bodilsen Leslie Foldager Peer Christiansen Source Type: research
Clinical implications of incorporating genetic and non-genetic risk factors in CanRisk-based breast cancer risk prediction
Breast. 2023 Nov 29;73:103615. doi: 10.1016/j.breast.2023.103615. Online ahead of print.ABSTRACTBACKGROUND: Breast cancer (BC) risk prediction models consider cancer family history (FH) and germline pathogenic variants (PVs) in risk genes. It remains elusive to what extent complementation with polygenic risk score (PRS) and non-genetic risk factor (NGRFs) data affects individual intensified breast surveillance (IBS) recommendations according to European guidelines.METHODS: For 425 cancer-free women with cancer FH (mean age 40·6 years, range 21-74), recruited in France, Germany and the Netherlands, germline PV status, NGRF...
Source: Breast - December 7, 2023 Category: Cancer & Oncology Authors: Anja T üchler Antoine De Pauw Corinna Ernst Am élie Anota Inge M M Lakeman Julia Dick Nienke van der Stoep Christi J van Asperen Monika Maringa Natalie Herold Britta Bl ümcke Robert Remy Anke Westerhoff Denise J Stommel-Jenner El éonore Frouin Lisa Ri Source Type: research
Clinical implications of incorporating genetic and non-genetic risk factors in CanRisk-based breast cancer risk prediction
Breast. 2023 Nov 29;73:103615. doi: 10.1016/j.breast.2023.103615. Online ahead of print.ABSTRACTBACKGROUND: Breast cancer (BC) risk prediction models consider cancer family history (FH) and germline pathogenic variants (PVs) in risk genes. It remains elusive to what extent complementation with polygenic risk score (PRS) and non-genetic risk factor (NGRFs) data affects individual intensified breast surveillance (IBS) recommendations according to European guidelines.METHODS: For 425 cancer-free women with cancer FH (mean age 40·6 years, range 21-74), recruited in France, Germany and the Netherlands, germline PV status, NGRF...
Source: Breast - December 7, 2023 Category: Cancer & Oncology Authors: Anja T üchler Antoine De Pauw Corinna Ernst Am élie Anota Inge M M Lakeman Julia Dick Nienke van der Stoep Christi J van Asperen Monika Maringa Natalie Herold Britta Bl ümcke Robert Remy Anke Westerhoff Denise J Stommel-Jenner El éonore Frouin Lisa Ri Source Type: research
Association of clinicopathologic variables and patient preference with the choice of surgical treatment for early-stage breast cancer: A registry-based study
CONCLUSION: Choice of surgery is strongly associated with key prognostic factors among women undergoing BCS with RT compared to mastectomy. Failure to control for all relevant confounders may bias results in outcome studies in favour of BCS.PMID:38056168 | DOI:10.1016/j.breast.2023.103614 (Source: Breast)
Source: Breast - December 6, 2023 Category: Cancer & Oncology Authors: Emma S öderberg Fredrik W ärnberg Anna-Karin Wennstig Greger Nilsson Hans Garmo Lars Holmberg Carl Blomqvist Malin Sund Charlotta Wadsten Source Type: research
Development and evaluation of a decision aid for women eligible for organized breast cancer screening according to international standards: A multi-method study
CONCLUSIONS: This decision aid complies with IPDASi standards and could help women eligible for breast screening in France make a shared decision with a specialized healthcare professional about whether or not to participate in organized breast screening.PMID:38056169 | DOI:10.1016/j.breast.2023.103613 (Source: Breast)
Source: Breast - December 6, 2023 Category: Cancer & Oncology Authors: Sandrine Hild Delphine Teign é Damien Fairier Yannick Ruelle Isabelle Aubin-Auger St éphanie Sidorkiewicz Marie Citrini Xavier Gocko Catherine Cerisey Emilie Ferrat C édric Rat Source Type: research
Association of clinicopathologic variables and patient preference with the choice of surgical treatment for early-stage breast cancer: A registry-based study
CONCLUSION: Choice of surgery is strongly associated with key prognostic factors among women undergoing BCS with RT compared to mastectomy. Failure to control for all relevant confounders may bias results in outcome studies in favour of BCS.PMID:38056168 | DOI:10.1016/j.breast.2023.103614 (Source: Breast)
Source: Breast - December 6, 2023 Category: Cancer & Oncology Authors: Emma S öderberg Fredrik W ärnberg Anna-Karin Wennstig Greger Nilsson Hans Garmo Lars Holmberg Carl Blomqvist Malin Sund Charlotta Wadsten Source Type: research
Development and evaluation of a decision aid for women eligible for organized breast cancer screening according to international standards: A multi-method study
CONCLUSIONS: This decision aid complies with IPDASi standards and could help women eligible for breast screening in France make a shared decision with a specialized healthcare professional about whether or not to participate in organized breast screening.PMID:38056169 | DOI:10.1016/j.breast.2023.103613 (Source: Breast)
Source: Breast - December 6, 2023 Category: Cancer & Oncology Authors: Sandrine Hild Delphine Teign é Damien Fairier Yannick Ruelle Isabelle Aubin-Auger St éphanie Sidorkiewicz Marie Citrini Xavier Gocko Catherine Cerisey Emilie Ferrat C édric Rat Source Type: research
Oncoplastic and reconstructive surgery in SENONETWORK Italian breast centers: lights and shadows
Breast. 2023 Nov 18;73:103601. doi: 10.1016/j.breast.2023.103601. Online ahead of print.NO ABSTRACTPMID:38043223 | DOI:10.1016/j.breast.2023.103601 (Source: Breast)
Source: Breast - December 3, 2023 Category: Cancer & Oncology Authors: Matteo Ghilli Andrea Vittorio Emanuele Lisa Marzia Salgarello Giovanni Papa Mario Rietjens Secondo Folli Annalisa Curcio Guglielmo Ferrari Francesco Caruso Vittorio Altomare Daniele Friedman Maria Carmen De Santis Fiorenza De Rose Bruno Meduri Francesca D Source Type: research
Oncoplastic and reconstructive surgery in SENONETWORK Italian breast centers: lights and shadows
Breast. 2023 Nov 18;73:103601. doi: 10.1016/j.breast.2023.103601. Online ahead of print.NO ABSTRACTPMID:38043223 | DOI:10.1016/j.breast.2023.103601 (Source: Breast)
Source: Breast - December 3, 2023 Category: Cancer & Oncology Authors: Matteo Ghilli Andrea Vittorio Emanuele Lisa Marzia Salgarello Giovanni Papa Mario Rietjens Secondo Folli Annalisa Curcio Guglielmo Ferrari Francesco Caruso Vittorio Altomare Daniele Friedman Maria Carmen De Santis Fiorenza De Rose Bruno Meduri Francesca D Source Type: research
