L-asparaginase from human breast milk Lactobacillus reuteri induces apoptosis using therapeutic targets Caspase-8 and Caspase-9 in breast cancer cell line
CONCLUSIONS: Breast milk L. reuteri L-asparaginase induces apoptosis via Cas8 and Cas9 upregulation in the breast cancer cell line. L. reuteri L-asparaginase treatment may be the hopeful approach for the management of breast cancer. Furthermore, the results may highlight the fact that the presence of L-asparaginase-producing L. reuteri isolates in human breast milk may aid in breast cancer improvement or even prevention.PMID:37638419 | DOI:10.3233/BD-220074 (Source: Breast Disease)
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Zaman Hussein Hassan Ibtesam Ghadban Auda Likaa Hamied Mahdi Source Type: research
Complications of severe breast deformities after a silicone injection over 20-year and a successful surgical treatment
This report presents a case of severe breast deformities as complications 20 years after silicone injections at an unreputable aesthetic center. During the surgery, the authors separately removed fluid (silicone) masses and reconstructed mammary glandular tissues. Breast reconstruction was performed by the anchor breast lift along with the functional preservation of the nipple-areola complex and the superomedial pedicle. The surgery entirely addressed complications after injecting a large amount of silicone. 6 months postoperatively, the surgical outcomes were satisfactory. The surgical excision should be done to remove si...
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Hoang Thanh Tuan Nguyen Anh Ngoc Luu Dang Ai Nguyen Van Luat Source Type: research
Prognostic factors of male breast cancer: A monocentric experience
CONCLUSION: Contrary to breast cancer in women, our study showed that Tunisian MBC have positive hormone receptors in all cases. Although the overexpression of HER2 was low (8.33%) and there was no case of triple negative MBC, the prognosis was poor because of T4 stage, involved nodes, SBR III and distant metastases.PMID:37638418 | DOI:10.3233/BD-220073 (Source: Breast Disease)
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Wala Ben Kridis Mayssa Lajnef Faida Bouattour Nabil Toumi Jamel Daoud Afef Khanfir Source Type: research
L-asparaginase from human breast milk Lactobacillus reuteri induces apoptosis using therapeutic targets Caspase-8 and Caspase-9 in breast cancer cell line
CONCLUSIONS: Breast milk L. reuteri L-asparaginase induces apoptosis via Cas8 and Cas9 upregulation in the breast cancer cell line. L. reuteri L-asparaginase treatment may be the hopeful approach for the management of breast cancer. Furthermore, the results may highlight the fact that the presence of L-asparaginase-producing L. reuteri isolates in human breast milk may aid in breast cancer improvement or even prevention.PMID:37638419 | DOI:10.3233/BD-220074 (Source: Breast Disease)
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Zaman Hussein Hassan Ibtesam Ghadban Auda Likaa Hamied Mahdi Source Type: research
Complications of severe breast deformities after a silicone injection over 20-year and a successful surgical treatment
This report presents a case of severe breast deformities as complications 20 years after silicone injections at an unreputable aesthetic center. During the surgery, the authors separately removed fluid (silicone) masses and reconstructed mammary glandular tissues. Breast reconstruction was performed by the anchor breast lift along with the functional preservation of the nipple-areola complex and the superomedial pedicle. The surgery entirely addressed complications after injecting a large amount of silicone. 6 months postoperatively, the surgical outcomes were satisfactory. The surgical excision should be done to remove si...
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Hoang Thanh Tuan Nguyen Anh Ngoc Luu Dang Ai Nguyen Van Luat Source Type: research
