Clinical presentations and outcomes of young women aged & lt;40 yrs with Ductal carcinoma in situ
CONCLUSION: Young women with DCIS tend to present with symptoms, with breast lump as the commonest symptom. Symptomatic patients tend to be associated with grade III tumours, compared to non-symptomatic patients. On long-term follow-up, mode of presentation was not statistically associated with recurrence.PMID:37807772 | DOI:10.3233/BD-230018 (Source: Breast Disease)
Source: Breast Disease - October 9, 2023 Category: Cancer & Oncology Authors: Zhiyan Yan Joanne Ngeow John Allen Geok Hoon Lim Source Type: research

Observational analysis of clinical and pathological characteristics and their prognostic impact in Mexican patients with breast cancer: A multi-center study
Breast Dis. 2023;42(1):305-313. doi: 10.3233/BD-230025.ABSTRACTBreast cancer is the most incidental and deadly neoplasm worldwide; in Mexico, very few epidemiologic reports have analyzed the pathological features and its impact on their clinical outcome. Here, we studied the relation between pathological features and the clinical presentation at diagnosis and their impact on the overall and progression-free survival of patients with breast cancer. For this purpose, we collected 199 clinical records of female patients, aged at least 18 years old (y/o), with breast cancer diagnosis confirmed by biopsy. We excluded patients w...
Source: Breast Disease - October 9, 2023 Category: Cancer & Oncology Authors: Anna Gozalishvilli-Boncheva Iv án R Gonzalez-Espinoza Abraham Castro-Ponce Omar A Bravo-Guti érrez Gabriela Ju árez-Salazar Ricardo I Montes-de-Oca-Moreda Evelyn Aguirre-Flores Marisela Coyotl-Huexotl Juan Orozco-Luis Mariana Chiquillo-Dom ínguez Juli Source Type: research

A controversial ER negative PR positive molecular subtype of breast carcinoma-Report of two cases
Breast Dis. 2023;42(1):315-318. doi: 10.3233/BD-230039.ABSTRACTER-/PR+ is a controversial subtype and is not formally recognised as molecular subtype of breast carcinoma. Few studies concluded that this subtype does not exist and is due to technical errors, however, in contrast others consider it to be distinct entity with different response to therapy and clinical outcome. It is also essential to know whether this subtype shows any distinct histomorphological features or prognosis.Therefore, the present two cases of controversial subtype ER-/PR+ breast cancer is being reported with both the cases showing neuroendocrinal d...
Source: Breast Disease - October 9, 2023 Category: Cancer & Oncology Authors: Smita Chandra Sanya Bhasin Sunil Saini Source Type: research

Quality of life assessment of breast cancer survivors in Northern Morocco: Rural-urban disparity
This article is a cross-sectional study of 216 women undergoing adjuvant hormone therapy for breast cancer in two oncology centers in northern Morocco. Quality of life (QoL) was assessed using the Functional Assessment of Cancer Therapy (FACT) questionnaire and its endocrine subscale (ES). The relationship between rural-urban status in our sample and QoL was assessed by linear regression analysis using sociodemographic and clinical variables as covariates. Our results show that physical and functional well-being are significantly (p < 0.001) higher in rural areas (24 and 29, respectively) than in urban areas (16 and 19,...
Source: Breast Disease - September 24, 2023 Category: Cancer & Oncology Authors: Fadoua El Battioui Fatima El Malki Said Barrijal Source Type: research

Prognostic factors of male breast cancer: A monocentric experience
CONCLUSION: Contrary to breast cancer in women, our study showed that Tunisian MBC have positive hormone receptors in all cases. Although the overexpression of HER2 was low (8.33%) and there was no case of triple negative MBC, the prognosis was poor because of T4 stage, involved nodes, SBR III and distant metastases.PMID:37638418 | DOI:10.3233/BD-220073 (Source: Breast Disease)
Source: Breast Disease - August 28, 2023 Category: Cancer & Oncology Authors: Wala Ben Kridis Mayssa Lajnef Faida Bouattour Nabil Toumi Jamel Daoud Afef Khanfir Source Type: research